Fig 1: Down-regulated miR-3682-3p inhibits the nodules grow and promotes apoptosis in MHCC-97H and SMMC-7721 cells in nude mice and results of apoptosis markers. (A) Nodules comparison figure in sh-miR-3682-3p and sh-NC group. (B) Week-measurement curves of nodules in each group. (C and D) Tumor weight and mice weight before sacrifice. (E, F and G) Representative IHC staining or fluorescein of nodules sections of Ki-67, Tunel and CASP8 in sh-miR-3682-3p and sh-NC cells. Bar figures indicate the statistics of number of lung nodules. Bar figures indicated the statistics. *P<0.05, **P<0.01. n= 3 independent experiments.