Anti-Factor VIII Antibody GMA-8016 from Green Mountain Antibodies

Product Specs
ItemAnti-Factor VIII Antibody
CompanyGreen Mountain Antibodies
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberGMA-8016
Quantity0.1 mg
ApplicationsELISA, IP, bio-layer interferometry
Conjugate/TagUnconjugated
FormatLyophilized from a ≥1 mg/ml solution in 20 mM NaH2PO4 0.15 M NaCl, 1.0% (w/v) mannitol, pH 7.4
Reactivityhuman
TargetFactor VIII, Factor VIII A2 domain
IsotypeIgG2a
Clone4C7
Hostmouse
ImmunogenFactor VIII
NCBI Full Gene Namecoagulation factor VIII
NCBI Gene AliasesAHF, DXS1253E, F8B, F8C, FVIII, HEMA
ClonalityMonoclonal

Add to Compare List

Green Mountain Antibodies

PO Box 1283

One Mill St, Burlington, VT 05402

United States

Phone: 802.865.6230
Fax: 802.865.0115

Email: Productsales@greenmoab.com

Company Profile

Website: https://greenmoab.com/

(1) Liver-directed lentiviral gene therapy corrects hemophilia A mice and achieves normal-range factor VIII activity in non-human primatesNature communicationsMay 4, 2022Milani M, Canepari C, Liu T, Biffi M, Russo F, Plati T, Curto R, Patarroyo-White S, Drager D, Visigalli I, et al.FVIII antigen. Microtiter plates were coated with anti-hFVIII binding Ab (Green Mountain Antibodies #GMA8016, 0.2 µg/well in 0.1 M carbonate buffer, pH 9.6) over night at 4 °C and then blocked 1 h at room temperature

(2) Identification of Key Coagulation Activity Determining Elements in Canine Factor VIIIMolecular Therapy. Methods & Clinical DevelopmentJanuary 15, 2020Jenni Firrman, Qizhao Wang, Wenman Wu, Biao Dong, Wenjing Cao, Andrea Rossi Moore, Sean Roberts, Barbara A. Konkle, Carol Miao, LinShu Liu, Dong Li, Weidong Xiaostandard. An ELISA was used to quantify FVIII antigen. Briefly, plates were coated with hHC antigen GMA-8016 or human LC antigen GMA-8018 (Green Mountain Antibodies), stored overnight at 4°C, and then replaced

(3) Evaluation of the biological differences of canine and human factor VIII in gene delivery: implications in human hemophilia treatmentGene TherapyJuly 1, 2016Qizhao Wang et al.

(4) Recombinant factor VIII Fc (rFVIIIFc) fusion protein reduces immunogenicity and induces tolerance in hemophilia A miceCellular ImmunologyMarch 1, 2016Sriram Krishnamoorthy et al.antibodies prepared by mixing equal amount of GMA8002 (A1), GMA8008 (C2), GMA8011 (C1), GMA8015 (A2), GMA8016 (A2), GMA8005 (A1/A3) (Green Mountain Antibodies Inc, Burlington, VT; FVIII domain epitopes in parenthesis).

(5) FcRn Rescues Recombinant Factor VIII Fc Fusion Protein from a VWF Independent FVIII Clearance Pathway in Mouse HepatocytesPloS oneJanuary 1, 2015van der Flier A, Liu Z, Tan S, Chen K, Drager D, Liu T, Patarroyo-White S, Jiang H, Light DR.murine FVIII (i.e. FcRn-chimeric mice), human FVIII was first captured by a human FVIII-specific mAb (GMA8016, Green Mountain Antibodies) followed by the FVIII chromogenic activity assay [2]. In PK studies of human

(6) A Single Chain Variant of Factor VIII Fc Fusion Protein Retains Normal In Vivo Efficacy but Exhibits Altered In Vitro ActivityPLoS ONENovember 21, 2014Yang Buyue, Tongyao Liu, John D. Kulman, Garabet G. Toby, George D. Kamphaus, Susannah Patarroyo-White, Qi Lu, Thomas J. Reidy, Baisong Mei, Haiyan Jiang, et al.HemA mouse efficacy study was done with a FVIII ELISA assay using a monoclonal anti-FVIII antibody GMA8016 (Green Mountain Antibodies, Burlington, VT). Thrombin generation assay Thrombin activity was determined

(7) The diversity of the immune response to the A2 domain of human factor VIIIBloodApril 4, 2013Rebecca C. Markovitz, John F. Healey, Ernest T. Parker, Shannon L. Meeks, Pete Lollar

(8) Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogsBloodMarch 29, 2012Jennifer A Dumont, Tongyao Liu, Susan C Low, Xin Zhang, George Kamphaus, Paul Sakorafas, Cara Fraley, Douglas Drager, Thomas Reidy, Justin McCue, Helen W G Franck, Elizabeth P Merricks, Timothy C Nichols, Alan J Bitonti, Glenn F Pierce, Haiyan Jiang

Be the First to Write a Review!

Anti-Factor VIII Antibody from Green Mountain Antibodies

Green Mountain Antibodies

Citations (8)

Reviews

Anti-Factor VIII Antibody from Green Mountain Antibodies

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map