Fig 1: Changes in the fractionation profiling of proteins from the mitochondrial matrix in UVA-exposed cells compared to controls reflect mitochondrial fragmentation(A) Profile plots obtained for FH and OAT in control and irradiated samples. Lines represent the means of relative abundance, and shadowed intervals represent standard errors.(B) Immunostaining of FH (green) in HaCaT cells exposed to UVA or mock-treated. PDHA1 (red) was immunolabeled as a structural mitochondrial marker. The nucleus was stained with Hoechst (blue). Three independent experiments were performed, and similar results were obtained.(C) Immunostaining of OAT (green) in HaCaT cells exposed to UVA or mock-treated. Similarly, PDHA1 (red) was used as a mitochondrial marker, and the nucleus was stained with Hoechst (blue). Three independent experiments were performed, and similar results were obtained. The bars indicate the 20 µm scale.