InVivoPlus anti-mouse PD-1 (CD279) BP0273-R050mg from Bio X Cell

Product Specs
ItemInVivoPlus anti-mouse PD-1 (CD279)
CompanyBio X Cell
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberBP0273-R050mg
Quantity50 mg
Applicationsin vivo blocking of PD-1/PD-L signaling, in vitro PD-1 neutralization, Immunohistochemistry (frozen), Immunofluorescence, Western blot, Flow cytometry
ConcentrationLot specific,typically between 4-11 mg/ml
Conjugate/TagUnconjugated
ReactivityMouse
TargetPD-1
IsotypeIgG2a
Clone29F.1A12™
Hostrat
NCBI Full Gene Nameprogrammed cell death 1
NCBI Gene AliasesLy101, PD-1, Pdc1
ClonalityMonoclonal
ImmunogenRecombinant PD-1-Ig fusion protein
Antibody TypePrimary Antibody
Purity>95%, Determined by SDS-PAGE
FormatPBS, pH 7.0, Contains no stabilizers or preservatives
Research AreaCancer Biology, Immune Checkpoint Protein, Immunology

Other available quantities: Available in 1, 5, 10, 25, 50, 100 mg and bulk sizes. Academic discount available.

Endotoxin: <1EU/mg (<0.001EU/µg), Determined by LAL gel clotting assay

39 Labombard Rd

Lebanon, NH 03766

United States

Phone: 1-866-787-3444

Email: customerservice@bxcell.com

(1) RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic CancerCancer cellNovember 12, 2018Wang W, Marinis JM, Beal AM, Savadkar S, Wu Y, Khan M, Taunk PS, Wu N, Su W, Wu J, et al.

(2) PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunityNatureMay 25, 2017Gordon SR, Maute RL, Dulken BW, Hutter G, George BM, McCracken MN, Gupta R, Tsai JM, Sinha R, Corey D, et al.

(4) Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpointsNature communicationsFebruary 17, 2016Koyama S, Akbay EA, Li YY, Herter-Sprie GS, Buczkowski KA, Richards WG, Gandhi L, Redig AJ, Rodig SJ, Asahina H, et al.

(5) Response to BRAF inhibition in melanoma is enhanced when combined with immune checkpoint blockadeCancer immunology researchJuly 1, 2014Cooper ZA, Juneja VR, Sage PT, Frederick DT, Piris A, Mitra D, Lo JA, Hodi FS, Freeman GJ, Bosenberg MW, et al.

(6) Negative role of inducible PD-1 on survival of activated dendritic cellsJournal of leukocyte biologyApril 1, 2014Park SJ, Namkoong H, Doh J, Choi JC, Yang BG, Park Y, Chul Sung Y.

(9) Role of the immune modulator programmed cell death-1 during development and apoptosis of mouse retinal ganglion cellsInvestigative ophthalmology & visual scienceOctober 1, 2009Chen L, Sham CW, Chan AM, Francisco LM, Wu Y, Mareninov S, Sharpe AH, Freeman GJ, Yang XJ, Braun J, et al.

(10) Programmed death 1 ligand (PD-L) 1 and PD-L2 limit autoimmune kidney disease: distinct rolesJournal of immunology (Baltimore, Md. : 1950)December 1, 2007Menke J, Lucas JA, Zeller GC, Keir ME, Huang XR, Tsuboi N, Mayadas TN, Lan HY, Sharpe AH, Kelley VR.

(11) Restoring function in exhausted CD8 T cells during chronic viral infectionNatureFebruary 9, 2006Barber DL, Wherry EJ, Masopust D, Zhu B, Allison JP, Sharpe AH, Freeman GJ, Ahmed R.

(12) Regulation of PD-1, PD-L1, and PD-L2 expression during normal and autoimmune responsesEuropean journal of immunologyOctober 1, 2003Liang SC, Latchman YE, Buhlmann JE, Tomczak MF, Horwitz BH, Freeman GJ, Sharpe AH.

InVivoPlus anti-mouse PD-1 (CD279)