CD49b (Integrin alpha 2) Antibody eFluor 450 48-5971-82 from Thermo Fisher Scientific

Product Specs
ItemCD49b (Integrin alpha 2) Antibody eFluor 450
CompanyThermo Fisher Scientific
Price Pricing Info Supplier Page View Company Product Page
Catalog Number48-5971-82
Quantity100 µg
ApplicationsFlow Cytometry
Concentration0.2 mg/mL
Conjugate/TageFluor™ 450
FormatPBS with 0.09% sodium azide; pH 7.2
ReactivityMouse
TargetCD49b (Integrin alpha 2)
IsotypeIgM kappa
CloneDX5
HostRat
NCBI Full Gene Nameintegrin alpha 2
NCBI Gene AliasesCD49B, DX5, GPIa
ClonalityMonoclonal
PurityAffinity chromatography
Storage Temperature4° C, store in dark, DO NOT FREEZE!
Antibody TypePrimary
Storage4° C, store in dark, DO NOT FREEZE!

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Thermo Fisher Scientific

81 Wyman Street

Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

Company Profile

Website: www.thermofisher.com

(1) Human IRF1 governs macrophagic IFN-γ immunity to mycobacteriaCellFebruary 2, 2023Rosain J, Neehus AL, Manry J, Yang R, Le Pen J, Daher W, Liu Z, Chan YH, Tahuil N, Türel Ö, et al.,Thermo Fisher Scientific,"Cat# 48-0452-82, RRID:AB_1548761" eFluor 450 Murine CD49b (clone DX5),Thermo Fisher Scientific,"Cat# 48-5971-82, RRID:AB_10671541" PE/Dazzle 594 Murine CD62L (clone MEL-14),BioLegend,"Cat# 104448, RRID:AB_2566163" BV786

(2) Glycosaminoglycans and fucoidan have a protective effect on experimental glomerulonephritisFrontiers in molecular biosciencesJanuary 1, 2023Buijsers B, Maciej-Hulme M, Jacobs M, Bebber MB, de Graaf M, Salmenov R, Parr N, Rabelink TJ, Nijenhuis T, van der Vlag J.Violet 650,Granulocytes,Cat#127641 Biolegend,AB_2565881 anti-CD49b,eFluor450,Lineage NK and T cells,Cat#48-5971-82 Thermo Fisher Scientific,AB_10671541 anti-CD90.2,eFluor450,Lineage T cells,Cat#48-0902-82 Thermo Fisher Scientific

(3) Linked sensitization by memory CD4+ T cells prevents costimulation blockade–induced transplantation toleranceJCI InsightJune 8, 2022Michael S. Andrade, James S. Young, Jared M. Pollard, Dengping Yin, Maria-Luisa Alegre, Anita S. Chongdead cells. An antibody cocktail was used to exclude unwanted cells, consisting of CD49b (DX5, catalog 485971-82, Invitrogen, Thermo Fisher Scientific), CD11c (N418, catalog 48-0114-82), F4/80 (BM8, catalog 48-4801-82,

(4) Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cellsThe Journal of experimental medicineAugust 2, 2021Hosokawa H, Koizumi M, Masuhara K, Romero-Wolf M, Tanaka T, Nakayama T, Rothenberg EV.

(5) The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitudeThe Journal of experimental medicineJune 7, 2021Li ZY, Morman RE, Hegermiller E, Sun M, Bartom ET, Maienschein-Cline M, Sigvardsson M, Kee BL.

(6) Pregnancy-induced humoral sensitization overrides T cell tolerance to fetus-matched allografts in miceJournal of Clinical InvestigationJanuary 4, 2021Ashley N. Suah et al.(Ter119, catalog 48-5921-82, eBioscience), F4/80 (BM8, catalog 48-480182, Invitrogen), CD49b (DX5, catalog 485971-82, Invitrogen), CD11c (N418, catalog 48-0114-82), CD90.2 (53-2.1, catalog 47-0902-82, Invitrogen), CD4

(7) Exosomes derived from retinoblastoma cells enhance tumour deterioration by infiltrating the microenvironmentOncology reportsJanuary 1, 2021Chen S, Chen X, Qiu J, Chen P, Han X, Wu Y, Zhuang J, Yang M, Wu C, Wu N, et al.

(8) Inflammation-Induced Lactate Leads to Rapid Loss of Hepatic Tissue-Resident NK CellsCell reportsJuly 7, 2020Dodard G, Tata A, Erick TK, Jaime D, Miah SMS, Quatrini L, Escalière B, Ugolini S, Vivier E, Brossay L.,Thermo Fisher Scientific,Cat#: 48-0032-82; RRID: AB_1272193 eF450 anti-mouse DX5,Thermo Fisher Scientific,Cat#: 48-5971-82; RRID: AB_10671541 eF450 anti-mouse IFN-γ,Thermo Fischer Scientific,Cat#: 48-7311-82; RRID: AB_1834366 FITC

(9) Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cellsThe Journal of clinical investigationJuly 1, 2020Khiew SH, Jain D, Chen J, Yang J, Yin D, Young JS, Dent A, Sciammas R, Alegre ML, Chong AS.cells per tube. The following antibodies were used for surface staining at 4°C: CD49b (DX5, catalog 485971-82, Invitrogen), CD11b (M1/70, catalog 101224, BioLegend), CD11c (N418, catalog 48-0114-82, eBioscience),

(10) MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironmentJournal for immunotherapy of cancerNovember 28, 2019Fang DD, Tang Q, Kong Y, Wang Q, Gu J, Fang X, Zou P, Rong T, Wang J, Yang D, et al.(Thermo Fisher, catalog #45–0081-82), CD3 (Thermo Fisher, catalog #11–0032-82), CD49b (Thermo Fisher, catalog #48–5971-82), CD11b (Thermo Fisher, catalog #48–0112-82), F4/80 (Thermo Fisher, catalog #17–4801-82), CD206 (Thermo Fisher

(11) Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple speciesScience Translational MedicineAugust 21, 2019Tina Binderup et al.TER119),eBioScience,48–5921–82 Anti-mouse NK1.1 (clone PK136),eBioScience,48–5941–82 Anti-mouse CD49b (clone DX5),eBioScience,48–5971–82 Anti-mouse CD45R/B220 (clone RA3–6B2),eBioScience,48–0452–82 Anti-mouse Ly6G (clone 1A8),BioLegend,127612

(12) A stochastic epigenetic switch controls the dynamics of T-cell lineage commitmenteLifeNovember 20, 2018Ng KK, Yui MA, Mehta A, Siu S, Irwin B, Pease S, Hirose S, Elowitz MB, Rothenberg EV, Kueh HY.17-5711-82; RRID:AB_842756,(1:300) Antibody,Anti-mouse CD49b eFluor 450 (clone DX5),eBioscience,Cat# 48-5971-82; RRID:AB_10671541,(1:300) Antibody,Anti-mouse NK1.1 APC (clone PK136),eBioscience,Cat# 17-5941-82;

(13) Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8⁺ T cell responsesJournal of controlled release : official journal of the Controlled Release SocietyJuly 28, 2018Si Y, Wen Y, Kelly SH, Chong AS, Collier JH.antibodies was used to further exclude unwanted cells. These antibodies included anti-DX5 (DX5, Cat# 48-5971-82, Thermo Fisher), anti-CD11b (M1/70, Cat# 101224, BioLegend), anti-F4/80 (BM8, Cat# 48-4801-82), anti-CD19

(14) Equal Expansion of Endogenous Transplant-Specific Regulatory T Cell and Recruitment Into the Allograft During Rejection and ToleranceFrontiers in immunologyJanuary 1, 2018Young JS, Yin D, Vannier AGL, Alegre ML, Chong AS.heart. Antibodies and Tetramers CD49b-eFluor450 (Thermo Fisher, Waltham, MA, USA, Clone DX5, Cat #485971-82), CD11b-eFluor450 (Biolegend, Dedham, MA, USA, Clone M1/70, Cat #101224), CD11c-eFluor450 (Thermo Fisher,

(15) 4PD Functionalized Dendrimers: A Flexible Tool for In Vivo Gene Silencing of Tumor-Educated Myeloid CellsJournal of immunology (Baltimore, Md. : 1950)May 15, 2017Zilio S, Vella JL, De la Fuente AC, Daftarian PM, Weed DT, Kaifer A, Marigo I, Leone K, Bronte V, Serafini P.

(16) CTLA4-Ig in combination with FTY720 promotes allograft survival in sensitized recipientsJCI insightMay 4, 2017Khiew SH, Yang J, Young JS, Chen J, Wang Q, Yin D, Vu V, Miller ML, Sciammas R, Alegre ML, et al.(Life Technologies) solution to exclude dead cells, and a cocktail of dump antibodies (DX5, catalog 48-5971-82), CD11b (M1/70, catalog 101224), F4/80 (BM8, catalog 48-480182), CD19 (1D3, catalog 48-0193-80), and

(17) DC subset-specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivoThe Journal of experimental medicineMay 1, 2017Lehmann CHK, Baranska A, Heidkamp GF, Heger L, Neubert K, Lühr JJ, Hoffmann A, Reimer KC, Brückner C, Beck S, et al.

(18) Spontaneous Chitin Accumulation in Airways and Age-Related Fibrotic Lung DiseaseCellApril 20, 2017Van Dyken SJ, Liang HE, Naikawadi RP, Woodruff PG, Wolters PJ, Erle DJ, Locksley RM.

(19) Differential regulation of C5a receptor 1 in innate immune cells during the allergic asthma effector phasePloS oneJanuary 1, 2017Ender F, Wiese AV, Schmudde I, Sun J, Vollbrandt T, König P, Laumonnier Y, Köhl J.

(20) The breast tumor microenvironment alters the phenotype and function of natural killer cellsCellular & molecular immunologySeptember 1, 2016Krneta T, Gillgrass A, Chew M, Ashkar AA.

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Clinical and experimental immunology

Clinical and experimental immunology

CD49b (Integrin alpha 2) Antibody eFluor 450 from Thermo Fisher Scientific

Thermo Fisher Scientific

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CD49b (Integrin alpha 2) Antibody eFluor 450 from Thermo Fisher Scientific

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