Fig 1: Characterization of NKT cells in the X-SCID patient's BMMNCs. (A) CD16 and CD56 levels of CD3+ NKT cells in the X-SCID patient. The NKT cells were positive with CD16 and/or CD56. (B) UMAP plot projecting the NKT cells from the X-SCID patient and the healthy donor. Each dot denotes an individual cell and colors represent the cell sources. The cell number in each origin was listed in Table SXIV. (C) Volcano plot showing the DEGs between this X-SCID patient and the healthy donor. The red and the green dots represented genes higher expressed in the X-SCID patient and in the healthy donor, respectively and the black dots represented genes not differentially expressed. The representative DEGs were highlighted and labeled. (D) Heatmap displaying the representative DEGs between the X-SCID patient and the healthy donor. (E) Violin plot showing the representative DEGs top expressed in either the X-SCID patient or the healthy donor. X-SCID, X-linked severe combined immunodeficiency; BMMNCs, bone marrow mononuclear cells; UMAP, uniform manifold approximation and projection; DEGs, differentially expressed genes.