CD279 (PD-1) Antibody eFluor 450 48-9981-82 from Thermo Fisher Scientific

Product Specs
ItemCD279 (PD-1) Antibody eFluor 450
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog Number48-9981-82
Quantity100 µg
ApplicationsFlow Cytometry
Concentration0.2 mg/mL
Conjugate/TageFluor™ 450
FormatPBS with 0.09% sodium azide; pH 7.2
ReactivityMouse
TargetCD279 (PD-1)
IsotypeIgG2b kappa
CloneRMP1-30
HostRat
NCBI Full Gene Nameprogrammed cell death 1
NCBI Gene AliasesLy101, PD-1, Pdc1
ClonalityMonoclonal
PurityAffinity chromatography
Storage Temperature4° C, store in dark, DO NOT FREEZE!
Antibody TypePrimary
Storage4°C, store in dark, DO NOT FREEZE!

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Website: www.thermofisher.com

(1) Glycolysis inhibition functionally reprograms T follicular helper cells and reverses lupusCell ReportsDecember 23, 2025Seung Chul Choi, Yong Ge, Ahmed Elshikha, Yuk Pheel Park, Cenxiao Fang, Milind V. Joshi, Maria Montes Montes de Oca Arena, Lauren Padilla, Yanan Zhu, William L. Clapp, et al.(ICOS)-PE,BD Biosciences,Cat#552146; RRID:AB_394349 Anti-mouse CD279 (PD-1)-eFluor 450,Thermo Fisher,Cat#48-9981-82; RRID:AB_11150068 Anti-mouse CD279 (PD-1)-BV785,BioLegend,Cat#135225; RRID:AB_2563680 Anti-human CD279

(2) Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastasesElifeJanuary 21, 2025Shih-Wen Huang, Yein-Gei Lai, Hao-Ting Liao, Chin-Ling Chang, Ruo-Yu Ma, Yung-Hsiang Chen, Yae-Huei Liou, Zhen-Qi Wu, Yu-Chen Wu, Ko-Jiunn Liu, et al.monoclonal),eBioscience,Cat#:12-5882-82 RRID:AB_465996,(1:50) Antibody,Anti-mouse PD-1 eFluor 450 (Rat monoclonal),eBioscience,Cat#:48-9981-82 RRID:AB_11150068,(1:50) Antibody,Anti-mouse PDCA1 Alexa Fluor 700 (Rat monoclonal),BioLegend,Cat#:127038

(3) The aged microenvironment impairs BCL6 and CD40L induction in CD4(+) T follicular helper cell differentiationAging cellJune 1, 2024Fisher JS, Adán-Barrientos I, Kumar NR, Lancaster JN.(Ser 235/236),Unconjugated,Polyclonal,Cell Signaling 2211S PD‐1/CD279,eFluor450,RMPI‐30,eBioscience 48‐9981‐82 PD‐1/CD279,FITC,29F.1A12,Biolegend 135213 PSGL‐1/CD162,BV605,2PH1,BD Biosciences 740384 T‐BET,PECy7,4B10,Biolegend

(4) BRAF D594A mutation defines a unique biological and immuno-modulatory subgroup associated with functional CD8(+) T cell infiltration in colorectal cancerJournal of translational medicineOctober 18, 2023Li W, Zhao C, Li W, Gong Y, Ma K, Lu Y, Liu X, Zhang L, Guo F.

(5) Oncolytic virus M1 functions as a bifunctional checkpoint inhibitor to enhance the antitumor activity of DC vaccineCell reports. MedicineOctober 17, 2023Dan J, Cai J, Zhong Y, Wang C, Huang S, Zeng Y, Fan Z, Xu C, Hu L, Zhang J, et al.

(6) Breast cancer cell-derived extracellular vesicles promote CD8(+) T cell exhaustion via TGF-β type II receptor signalingNature communicationsAugust 1, 2022Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, et al.

(7) Immune Mechanisms of Resistance to Cediranib in Ovarian CancerMolecular cancer therapeuticsJune 1, 2022Gopinathan G, Berlato C, Lakhani A, Szabova L, Pegrum C, Pedrosa AR, Laforets F, Maniati E, Balkwill FR.anti-F4/80 PE (Biolegend,123110), anti-CD19 PE Dazzle (Biolegend,115534), anti–PD-1 e450 (eBioscience, 48–9981–82), anti–PD-L1 (BV421, Biolegend,374508), anti-MR FITC (Biolegend,141704), and anti-MHCII APC-Cy7 (Biolegend,107628).

(8) Functional assessment of the cell-autonomous role of NADase CD38 in regulating CD8(+) T cell exhaustioniScienceMay 20, 2022Ma K, Sun L, Shen M, Zhang X, Xiao Z, Wang J, Liu X, Jiang K, Xiao-Feng Qin F, Guo F, et al.

(9) Anti-PD-1 Checkpoint Therapy Can Promote the Function and Survival of Regulatory T CellsJournal of immunology (Baltimore, Md. : 1950)November 15, 2021Vick SC, Kolupaev OV, Perou CM, Serody JS.monoclonal antibodies against murine CD45 (30-F11 #11-0451-82), Foxp3 (FJK-16S #45-5773-82), PD-1 (J43 #48-9981-82), Ki67 (SolA15 #17-5698-80), Thy1.1 (HIS51 #45-0900-80), CTLA-4 (UC10-4B9 # 12-1522-82), and GITR (DTA-1

(10) M2 macrophage-derived extracellular vesicles facilitate CD8+T cell exhaustion in hepatocellular carcinoma via the miR-21-5p/YOD1/YAP/β-catenin pathwayCell death discoveryJuly 16, 2021Pu J, Xu Z, Nian J, Fang Q, Yang M, Huang Y, Li W, Ge B, Wang J, Wei H.

(11) Evidence for Non-Cancer-Specific T Cell Exhaustion in the Tcl1 Mouse Model for Chronic Lymphocytic LeukemiaInternational journal of molecular sciencesJune 22, 2021Parigger T, Gassner FJ, Scherhäufl C, Bakar AA, Höpner JP, Hödlmoser A, Steiner M, Catakovic K, Geisberger R, Greil R, et al.MEL-14, cat: 11-0621-85 (Invitrogen, Carlsbad, CA, USA); anti-mouse PD1 eFluor 450, clone: RMP1-30, cat: 48-9981-82 (eBiosciences, San Diego, CA, USA). For flow cytometry of EDTA peripheral blood, 10–20 µL blood was

(12) Combination of vasculature targeting, hypofractionated radiotherapy, and immune checkpoint inhibitor elicits potent antitumor immune response and blocks tumor progressionJournal for immunotherapy of cancerFebruary 1, 2021Pierini S, Mishra A, Perales-Linares R, Uribe-Herranz M, Beghi S, Giglio A, Pustylnikov S, Costabile F, Rafail S, Amici A, et al.

(13) Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic targetJCI insightAugust 20, 2020Pierini S, Tanyi JL, Simpkins F, George E, Uribe-Herranz M, Drapkin R, Burger R, Morgan MA, Facciabene A.

(14) Regulatory CD8 T cells that recognize Qa-1 expressed by CD4 T-helper cells inhibit rejection of heart allograftsProceedings of the National Academy of Sciences of the United States of AmericaMarch 17, 2020Choi JY, Eskandari SK, Cai S, Sulkaj I, Assaker JP, Allos H, AlHaddad J, Muhsin SA, Alhussain E, Mansouri A, et al.anti–Qa-1-BV510 (6A8.6F10.1A6, #744386) were purchased from BD Biosciences. The anti–PD-1eFluor450 (RMP1-30, #48–9981-82) was purchased from eBioscience. FACS Canto II (BD Biosciences) was used for flow cytometry and the

(15) Cancer associated fibroblast FAK regulates malignant cell metabolismNature communicationsMarch 10, 2020Demircioglu F, Wang J, Candido J, Costa ASH, Casado P, de Luxan Delgado B, Reynolds LE, Gomez-Escudero J, Newport E, Rajeeve V, et al.

(16) Creatine uptake regulates CD8 T cell antitumor immunityThe Journal of experimental medicineDecember 2, 2019Di Biase S, Ma X, Wang X, Yu J, Wang YC, Smith DJ, Zhou Y, Li Z, Kim YJ, Clarke N, et al.

(17) Intestinal non-canonical NFκB signaling shapes the local and systemic immune responseNature communicationsFebruary 8, 2019Ramakrishnan SK, Zhang H, Ma X, Jung I, Schwartz AJ, Triner D, Devenport SN, Das NK, Xue X, Zeng MY, et al.

(18) Affinity Maturation Is Impaired by Natural Killer Cell Suppression of Germinal CentersCell reportsSeptember 25, 2018Rydyznski CE, Cranert SA, Zhou JQ, Xu H, Kleinstein SH, Singh H, Waggoner SN.AB_493699 Mouse anti-CD44 BV510,Biolegend,103044; RRID: AB_2650923 Mouse anti-PD-1 ef450,eBiosciences,48-9981-82; RRID: AB_2574139 Mouse anti-CXCR5 PE-Cy7,Biolegend,145516; RRID: AB_2562209 Mouse anti-CD49d FITC,Biolegend,103606;

(19) Non-conventional Inhibitory CD4⁺Foxp3^-PD-1^hi T Cells as a Biomarker of Immune Checkpoint Blockade ActivityCancer cellJune 11, 2018Zappasodi R, Budhu S, Hellmann MD, Postow MA, Senbabaoglu Y, Manne S, Gasmi B, Liu C, Zhong H, Li Y, et al.(clone 1D3),BD Biosciences,Cat# 551001 ef450-labeled anti-mouse PD-1 (clone RMP1-30),eBioscience,Cat# 48-9981-82 PE-labeled anti-mouse PD-1 (clone RMP1-30),eBioscience,Cat# 12-9981-83 APC-labeled anti-mouse PD-1

(20) Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 AntibodiesCancer cellApril 9, 2018Arce Vargas F, Furness AJS, Litchfield K, Joshi K, Rosenthal R, Ghorani E, Solomon I, Lesko MH, Ruef N, Roddie C, et al.

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CD279 (PD-1) Antibody eFluor 450

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CD279 (PD-1) Antibody eFluor 450 from Thermo Fisher Scientific

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CD279 (PD-1) Antibody eFluor 450 from Thermo Fisher Scientific

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