Fig 2: ASAH1-stainings in kidney biopsy specimen. (A–C) specimen from a male FD patient (34 years of age) with a classical phenotype with progressive loss of eGFR and macroalbuminuria showing increased ASAH1 expression in the tubular epithelial cells, but not in the glomeruli (g). (D) Male non-FD control patient (50 years of age) with chronic renal insufficiency due to hypertensive nephropathy. (E,F) Male non-FD control patient (51 years of age) with normal renal tissue adjacent to a primary kidney tumor (with primary antibody, (E), and negative control without primary antibody, (F).