Fig 1: Effect of berberine on the phosphorylation of p38 MAPK (A), ERK 1/2 (B), STAT3 (C), and IkB-a (D) in poly I:C-induced RAW 264.7 cells. After 24 h incubation, the phosphorylation of p38 MAPK, ERK 1/2, STAT3, and IkB-a was measured by Flow Cytometric Analysis. Normal group (Nor) was treated with media only. Control group (Con) was treated with poly I:C (50 µg/mL) alone. Ba25 denotes baicalein (25 µM). Ber10, Ber25, and Ber50 mean 10, 25, and 25 µM of berberine, respectively. Values are the mean ± SD of three independent experiments. ###p < 0.001 vs. Nor; #p < 0.05 vs. Nor; ***p < 0.001 vs. Con; **p < 0.01 vs. Con; *p < 0.05 vs. Con.