Fig 1: COL1A1 is a key player of liver cancer cell invasiveness via ZEB1-mediated EMT.A Western blots. B–D SNU449 cells were transfected with siRNAs against COL1A1 (B), DDR1 (C), and ZEB1 (D). B, C Western blots (left), qRT-PCR (middle, N = 4), and cell invasiveness [right, N = 3 for (B) and N = 4 for (C)]. *p < 0.05 and **p < 0.01 vs. siNC. D Western blots (top) and cell invasiveness (bottom, N = 3). **p < 0.01 vs. siNC. E Scatter plots of the associations of MRPS31 expression with the indicated genes. The statistical r and p values by Pearson’s product-moment correlation test are depicted. F KM curves with OS. TCGA-LIHC samples were stratified into high or low expression group (upper or lower quartile) of the indicated genes (top). The high expression groups of the individual genes were further stratified into MRPS31 high or low expression group by using median values (bottom). The statistical p values by Cox-Mantel log-rank test are depicted.