Anti-Influenza A virus PA protein antibody GTX118991 from GeneTex

Product Specs
ItemAnti-Influenza A virus PA protein antibody
CompanyGeneTex
Price Pricing Info Supplier Page
Catalog NumberGTX118991
Quantity100 µl
ApplicationsWB, ICC/IF
Concentration0.91mg/ml
Conjugate/TagUnconjugated
PurityPurified by antigen-affinity chromatography
ReactivityInfluenza A virus
TargetInfluenza A virus PA protein
IsotypeIgG
HostRabbit
Antibody TypePrimary Antibodies
ImmunogenRecombinant protein encompassing a sequence within the C-terminus region of Influenza A virus PA (A/WSN/1933(H1N1)). The exact sequence is proprietary
ClonalityPolyclonal
Research AreaInfectious Diseases
FormatPBS, 20% Glycerol, 0.025% ProClin 300
NCBI Full Gene NameInfluenza A virus ( H1N1) polymerase PA
Molecular Weight83
NCBI Gene AliasesInfluenza A Virus Polymerase acidic protein, Influenza A Virus PA

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GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) An Influenza A virus can evolve to use human ANP32E through altering polymerase dimerizationNature CommunicationsOctober 10, 2023Carol M. Sheppard, Daniel H. Goldhill, Olivia C. Swann, Ecco Staller, Rebecca Penn, Olivia K. Platt, Ksenia Sukhova, Laury Baillon, Rebecca Frise, Thomas P. Peacock, et al.(GeneTex GTX125926, 1:2000), rabbit α-IAV PB1 (GeneTex GTX125923, 1:500), rabbit α-IAV PA (GeneTex GTX118991 1:500) mouse α-FLAG (Sigma-Aldrich F1804, 1:500), rabbit α-Gaussia luciferase (Invitrogen; PA1-18, 1:1000).

(2) Targeting influenza A virus by splicing inhibitor herboxidiene reveals the importance of subtype-specific signatures around splice sitesJournal of biomedical scienceFebruary 3, 2023Han YJ, Lee KM, Wu GH, Gong YN, Dutta A, Shih SR.(dilution factor: 1:1000), and LC3 (dilution factor: 1:2000) (Catalog numbers: GTX127356, GTX125951, GTX118991, and GTX127375, respectively; GeneTex, Irvine, CA, USA) and monoclonal antibodies against actin (dilution

(3) SRSF5-Mediated Alternative Splicing of M Gene is Essential for Influenza A Virus Replication: A Host-Directed Target Against Influenza VirusAdvanced science (Weinheim, Baden-Wurttemberg, Germany)December 1, 2022Li Q, Jiang Z, Ren S, Guo H, Song Z, Chen S, Gao X, Meng F, Zhu J, Liu L, et al.Bioscience, CB100127), influenza virus M1 (GeneTex, GTX125928), M2 (GeneTex, GTX125951), PA (GeneTex, GTX118991), PB1 (GeneTex, GTX125923), PB2 (GeneTex, GTX125926), NP (GeneTex, GTX125989), control rabbit IgG polyclonal

(4) Multi-Omics-Guided Discovery of Omicsynins Produced by Streptomyces sp. 1647: Pseudo-Tetrapeptides Active Against Influenza A Viruses and Coronavirus HCoV-229EEngineering (Beijing, China)September 1, 2022Sun H, Li X, Chen M, Zhong M, Li Y, Wang K, Du Y, Zhen X, Gao R, Wu Y, et al.3700S; 1:5000; Cell Signaling Technology, USA) and IAV polymerase acidic (PA) protein (antibody cat. No. GTX118991; 1:1000; GeneTex, USA) was performed as described previously [16]. 2.5.5 Time-of-addition assay A

(5) Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defenseCell reportsMarch 22, 2022Fernbach S, Spieler EE, Busnadiego I, Karakus U, Lkharrazi A, Stertz S, Hale BG.Sigma-Aldrich), PB1 (rabbit, catalog no. GTX125923; Genetex), PB2 (rabbit, inhouse), PA (rabbit, catalog no. GTX118991; Genetex), NP (mouse HB65, catalog no. H16-L10-4R5, ATCC), V5 (mouse, catalog no. MCA1360; Bio-Rad),

(6) p21 restricts influenza A virus by perturbing the viral polymerase complex and upregulating type I interferon signalingPLoS pathogensFebruary 1, 2022Ma C, Li Y, Zong Y, Velkov T, Wang C, Yang X, Zhang M, Jiang Z, Sun H, Tong Q, et al.China); anti-NP monoclonal antibody (mAb) was purchased from GenScript (Nanjing, China); and anti-PA (GTX118991), anti-PB1 (GTX125923) and anti-PB2 (GTX125926) antibodies were purchased from GeneTex (Irvine, CA,

(7) Evidence that two instead of one defective interfering RNA in influenza A virus-derived defective interfering particles (DIPs) does not enhance antiviral activityScientific reportsOctober 14, 2021Bdeir N, Arora P, Gärtner S, Pöhlmann S, Winkler M.

(8) MARCH8 inhibits influenza A virus infection by targeting viral M2 protein for ubiquitination-dependent degradation in lysosomesNature communicationsJuly 20, 2021Liu X, Xu F, Ren L, Zhao F, Huang Y, Wei L, Wang Y, Wang C, Fan Z, Mei S, et al.

(9) Interaction of NEP with G Protein Pathway Suppressor 2 Facilitates Influenza A Virus Replication by Weakening the Inhibition of GPS2 to RNA Synthesis and Ribonucleoprotein AssemblyJournal of virologyApril 26, 2021Gong W, He X, Huang K, Zhang Y, Li C, Yang Y, Zou Z, Jin M.polyclonal antibodies against IAV proteins PB1, PB2, PA, NP, and NEP (catalog nos. GTX125923, GTX125926, GTX118991, GTX125989, and GTX125928, respectively; GeneTex, USA); and Alexa Fluor 488-conjugated AffiniPure goat

(10) 8-O-(E-p-methoxycinnamoyl)harpagide Inhibits Influenza A Virus Infection by Suppressing Intracellular CalciumMolecules (Basel, Switzerland)February 15, 2021Kwon EB, Yang HJ, Kim YS, Li W, Choi JG.

(11) Eukaryotic Translation Elongation Factor 1 Delta Inhibits the Nuclear Import of the Nucleoprotein and PA-PB1 Heterodimer of Influenza A VirusJournal of virologyDecember 22, 2020Gao Q, Yang C, Ren C, Zhang S, Gao X, Jin M, Chen H, Ma W, Zhou H.

(12) PA Mutations Inherited during Viral Evolution Act Cooperatively To Increase Replication of Contemporary H5N1 Influenza Virus with an Expanded Host RangeJournal of virologyDecember 9, 2020Arai Y, Kawashita N, Elgendy EM, Ibrahim MS, Daidoji T, Ono T, Takagi T, Nakaya T, Matsumoto K, Watanabe Y.

(13) Type-IInterferon-Inducible SERTAD3 Inhibits Influenza A Virus Replication by Blocking the Assembly of Viral RNA Polymerase ComplexCell reportsNovember 3, 2020Sun N, Li C, Li XF, Deng YQ, Jiang T, Zhang NN, Zu S, Zhang RR, Li L, Chen X, et al.

(14) PA-X protein of H5N1 avian influenza virus inhibits NF-kappaB activity, a potential mechanism for PA-X counteracting the host innate immune responsesVeterinary microbiologyNovember 1, 2020Hu J, Kong M, Cui Z, Gao Z, Ma C, Hu Z, Jiao X, Liu X.

(15) Human TRA2A determines influenza A virus host adaptation by regulating viral mRNA splicingScience advancesJune 1, 2020Zhu Y, Wang R, Yu L, Sun H, Tian S, Li P, Jin M, Chen H, Ma W, Zhou H.California Bioscience, Coachella, CA, USA); rabbit anti-IAV PA, PB1, PB2, NP, NS1, M1, NEP, M2, HA (GTX118991, GTX125923, GTX125926, GTX125989, GTX125990, GTX125928, GTX125953, GTX125951, and GTX127357, GeneTex,

(16) Chemical intervention of influenza virus mRNA nuclear exportPLoS pathogensApril 1, 2020Esparza M, Mor A, Niederstrasser H, White K, White A, Zhang K, Gao S, Wang J, Liang J, Sho S, et al.virions (Meridian Life Science B65141G), M1 and M2 (Thermo MA1-082), NA (GeneTex GTX125974), PA (GeneTex GTX118991), PB1 (Santa Cruz sc-17601), PB2 (Santa Cruz sc-17603), and NS1 (a gift from J.A. Richt, National Animal

(17) The PB2 and M genes are critical for the superiority of genotype S H9N2 virus to genotype H in optimizing viral fitness of H5Nx and H7N9 avian influenza viruses in miceTransboundary and emerging diseasesMarch 1, 2020Hao X, Hu J, Wang X, Gu M, Wang J, Liu D, Gao Z, Chen Y, Gao R, Li X, et al.

(18) Dynamic Changes in pStat3 are Involved in Meiotic Spindle Assembly in Mouse OocytesInternational journal of molecular sciencesFebruary 12, 2020Haraguchi S, Ikeda M, Akagi S, Hirao Y.

(19) Viral Determinants in H5N1 Influenza A Virus Enable Productive Infection of HeLa CellsJournal of virologyJanuary 31, 2020Rodriguez-Frandsen A, Martin-Sancho L, Gounder AP, Chang MW, Liu WC, De Jesus PD, von Recum-Knepper J, Dutra MS, Huffmaster NJ, Chavarria M, et al.immunoblotted with the following primary antibodies: a rabbit polyclonal antibody against PA (catalog no. GTX118991; GeneTex), a rabbit polyclonal antibody against NP (described in reference 55), a mouse monoclonal antibody

(20) Avian Chaperonin Containing TCP1 Subunit 5 Supports Influenza A Virus Replication by Interacting With Viral Nucleoprotein, PB1, and PB2 ProteinsFrontiers in microbiologyJanuary 1, 2020Zhang X, Lin X, Qin C, Huang K, Sun X, Zhao L, Jin M.

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Anti-Influenza A virus PA protein antibody

Anti-Influenza A virus PA protein antibody

Anti-Influenza A virus PA protein antibody from GeneTex

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Anti-Influenza A virus PA protein antibody from GeneTex

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