Anti-Lamin A + C antibody GTX101127 from GeneTex

Product Specs
ItemAnti-Lamin A + C antibody
CompanyGeneTex
Price Pricing Info Supplier Page
Catalog NumberGTX101127
Quantity100 µl
ApplicationsWB, ICC/IF, IHC-P, IP
Concentration0.16mg/ml
Conjugate/TagUnconjugated
PurityPurified by antigen-affinity chromatography
ReactivityHuman, Mouse, Rat
TargetLamin A + C
IsotypeIgG
HostRabbit
Antibody TypePrimary Antibodies
ImmunogenRecombinant protein encompassing a sequence within the center region of Human Lamin A + C. The exact sequence is proprietary
NCBI Full Gene Namelamin A/C
NCBI Gene AliasesEMD2, CMD1A, LDP1, MADA, FPL, LMN1, lamin A/C, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, MADA, PRO1, CDCD1, LMNL1, CDDC, HGPS, CMT2B1, PRO1, LMNC, FPLD2, LGMD1B, IDC, FPLD, LFP
ClonalityPolyclonal
FormatPBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300
Research AreaCell Biology, Organelle Markers
Gene NameLMNA
Molecular Weight74

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GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasisScience advancesApril 14, 2023Hsu PL, Chien CW, Tang YA, Lin BW, Lin SC, Lin YS, Chen SY, Sun HS, Tsai SJ.1:200 for IF), β-actin (GeneTex, GTX109639, RRID:AB_1949572, 1:10,000 for WB), lamin A/C (GeneTex, GTX101127, RRID:AB_10729290, 1:10,000 for WB), CD31 (Bioss, BS-0468R, RRID:AB_10885355, 1:200 for IF; BD Biosciences,

(2) A G-quadruplex stabilizer, CX-5461 combined with two immune checkpoint inhibitors enhances in vivo therapeutic efficacy by increasing PD-L1 expression in colorectal cancerNeoplasia (New York, N.Y.)January 1, 2023Chung SY, Chang YC, Hsu DS, Hung YC, Lu ML, Hung YP, Chiang NJ, Yeh CN, Hsiao M, Soong J, et al.Cell Signaling #13647; NF-κB, Cell Signaling #8242; p-NF-κB (ser536), Cell Signaling #3033; Lamin A/C, Genetex #GTX101127; p-STAT1 (Try701), Cell Signaling #9167; STAT1, Santa Cruz #sc-417; PD-L1, Genetex #GTX104763, Abcam

(3) TFEB- and TFE3-dependent autophagy activation supports cancer proliferation in the absence of centrosomesAutophagyDecember 1, 2022Kao CH, Su TY, Huang WS, Lu XY, Jane WN, Huang CY, Huang HH, Wang WJ.

(4) CD44 Promotes Breast Cancer Metastasis through AKT-Mediated Downregulation of Nuclear FOXA2BiomedicinesOctober 5, 2022Vadhan A, Hou MF, Vijayaraghavan P, Wu YC, Hu SC, Wang YM, Cheng TL, Wang YY, Yuan SF.

(5) Relevance of AIF/CypA Lethal Pathway in SH-SY5Y Cells Treated with StaurosporineInternational journal of molecular sciencesDecember 27, 2021Conte M, Palumbo R, Monti A, Fontana E, Nebbioso A, Ruvo M, Altucci L, Doti N.

(6) 8-Hydroxydaidzein Downregulates JAK/STAT, MMP, Oxidative Phosphorylation, and PI3K/AKT Pathways in K562 CellsBiomedicinesDecember 14, 2021Wu PS, Wang CY, Chen PS, Hung JH, Yen JH, Wu MJ.,Cell Signaling,9134 AKT,Cell Signaling,9272 p-AKT,Cell Signaling,9271 c-Myc,Cell Signaling,5605 Lamin A/C,Genetex,GTX101127 Primary antibodies used for Western blotting.

(7) FJU-C28 inhibits the endotoxin-induced pro-inflammatory cytokines expression via suppressing JNK, p38 MAPK and NF-κB signaling pathwaysPharmacology research & perspectivesDecember 1, 2021Jung F, Liu JS, Yang SH, Tseng HY, Chou SP, Lin JC, Jow GM.

(8) MTHFR Knockdown Assists Cell Defense against Folate Depletion Induced Chromosome Segregation and Uracil Misincorporation in DNAInternational journal of molecular sciencesAugust 30, 2021Wu MT, Ye WT, Wang YC, Chen PM, Liu JY, Tai CK, Tang FY, Li JR, Liu CC, Chiang EI.MA, USA, Essex), anti-Actin (1:5000; NB600-501; Novus, Littleton, CO, USA), anti–Lamin A/C (1:1000; GTX101127; GeneTex, Irvine, CA, USA, Orange), anti-p53 (1:1000; #9282; Cell Signaling, Danvers, MA, USA, Essex),

(9) Etoposide Triggers Cellular Senescence by Inducing Multiple Centrosomes and Primary Cilia in Adrenocortical Tumor CellsCellsJune 11, 2021Teng YN, Chang HC, Chao YY, Cheng HL, Lien WC, Wang CY.signaling Cell signaling Cell signaling Cell signaling GeneTex #9284 sc-6243 ab7960-1 GTX26276 ab16048 GTX101127 T6557 T6793 ab2893 GTX70103 ab81292 sc-9051 sc-101664 #2790 #2853 #3440 #2661 #12741 NBP1-81445 #12302 #2360 #4691 #4060 GTX112141 2.7.

(10) Histone deacetylase 7 mediates endothelin-1-induced connective tissue growth factor expression in human lung fibroblasts through p300 and activator protein-1 activationJournal of biomedical scienceMay 19, 2021Hua HS, Wen HC, Weng CM, Lee HS, Chen BC, Lin CH.

(11) High Mobility Group Box 1 Promotes Lung Cancer Cell Migration and Motility via Regulation of Dynamin-Related Protein 1International journal of molecular sciencesMarch 31, 2021Liu WL, Li CY, Cheng WC, Chang CY, Chen YH, Lu CY, Wang SC, Liu YR, Cheng MH, Chong IW, et al.Santa Cruz Biotechnology, CA, USA), α-tubulin (1:2000; T5168, Sigma, Louis, MO, USA), Lamin A/C (1:1000, GTX101127, GeneTex, Irvine, CA, USA), and α-actin (1:2000, sc-137179, Santa Cruz Biotechnology) were used. 4.5.

(12) Downregulation of ARID1A in gastric cancer cells: a putative protective molecular mechanism against the Harakiri-mediated apoptosis pathwayVirchows Archiv : an international journal of pathologyMarch 1, 2021Sakuratani T, Takeuchi T, Yasufuku I, Iwata Y, Saigo C, Kito Y, Yoshida K.

(13) Nuclear lipid droplets form in the inner nuclear membrane in a seipin-independent mannerThe Journal of cell biologyJanuary 4, 2021Sołtysik K, Ohsaki Y, Tatematsu T, Cheng J, Maeda A, Morita SY, Fujimoto T.Laboratories), rabbit anti-actin (A2066; Sigma), rabbit anti-TRA2B (GTX114752; GeneTex), rabbit anti–lamin A/C (GTX101127; GeneTex), goat anti-MTP (sc-33116; Santa Cruz Biotechnology), and goat anti-Sec61α (sc-12322; Santa Cruz Biotechnology

(14) Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genesTheranosticsJanuary 1, 2021Hsu SC, Chen CL, Cheng ML, Chu CY, Changou CA, Yu YL, Yeh SD, Kuo TC, Kuo CC, Chuu CP, et al.H3K36me2 (39255), H3K36me3 (61101) from Active Motif; α tubulin (sc-23948) from Santa Cruz; Lamin A/C (GTX101127) from GeneTex. α tubulin was in 1:20000 dilution. For Lamin A/C and all histone-related antibodies,

(15) 8-Hydroxydaidzein, an Isoflavone from Fermented Soybean, Induces Autophagy, Apoptosis, Differentiation, and Degradation of Oncoprotein BCR-ABL in K562 CellsBiomedicinesNovember 16, 2020Wu PS, Yen JH, Wang CY, Chen PY, Hung JH, Wu MJ.Signaling,9492 CDK6,Cell Signaling,13331 Cyclin D2,Cell Signaling,3741 JNK2,Cell Signaling,9258 Lamin A/C,Genetex,GTX101127 LC3B,Genetex,GTX127375 P21,Cell Signaling,2947 p38 MAPK,Cell Signaling,9212 p44/42 MAP Kinase,Cell

(16) Particulate matters increase epithelial-mesenchymal transition and lung fibrosis through the ETS-1/NF-κB-dependent pathway in lung epithelial cellsParticle and fibre toxicologyAugust 14, 2020Chen YC, Chuang TY, Liu CW, Liu CW, Lee TL, Lai TC, Chen YL.

(17) Proteomic analysis of Antrodia Cinnamomea-induced ER stress in liver cancer cellsJournal of pharmaceutical and biomedical analysisAugust 5, 2020Chen JF, Tsai YT, Lai YH, Lin CC, Chou HC, Kuo WH, Ko ML, Wei YS, Wang YS, Lin MW, et al.

(18) H₂O₂-preconditioned human adipose-derived stem cells (HC016) increase their resistance to oxidative stress by overexpressing Nrf2 and bioenergetic adaptationStem cell research & therapyAugust 3, 2020Garrido-Pascual P, Alonso-Varona A, Castro B, Burón M, Palomares T.

(19) MiR-181d-5p Targets KLF6 to Improve Ischemia/Reperfusion-Induced AKI Through Effects on Renal Function, Apoptosis, and InflammationFrontiers in physiologyJanuary 1, 2020Zhang Y, Li C, Guan C, Zhou B, Wang L, Yang C, Zhen L, Dai J, Zhao L, Jiang W, et al.anti-IL-6,1:1,000, 12912, CST, United States; anti-TNF-α, 1:1,000, 3707S, CST, United States; anti-lamin A, 1:1,000, GTX101127, GeneTex, United States]. After TBST washing twice, the secondary antibody was goat anti-rabbit IgG-HRP

(20) Non-proliferative neurogenesis in human periodontal ligament stem cellsScientific reportsDecember 2, 2019Bueno C, Martínez-Morga M, Martínez S.1/300, Zymed), Synapsin1 (NB300-104; 1/300, Novus), Fibrillarin (ab5821; 1/300, Abcam) and Lamin A/C (GTX101127; 1/300, GeneTex) in PBS containing 1% normal horse serum and 0.25% Triton X-100. On the next day, cells

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Anti-Lamin A + C antibody

Anti-Lamin A + C antibody from GeneTex

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Anti-Lamin A + C antibody from GeneTex

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