PE anti-human TCR alpha/beta 306708 from BioLegend

Product Specs
ItemPE anti-human TCR alpha/beta
CompanyBioLegend
Price Pricing Info Supplier Page View Company Product Page
Catalog Number306708
NCBI Gene AliasesTCRA, IMD7, TCRB, TRB@, TRA@
ReactivityHuman
IsotypeIgG1, Kappa
ApplicationsFlow Cytometry (FC)
HostMouse
Conjugate/TagPE
CloneIP26
Quantity100 tests
Antibody TypePrimary
NCBI Full Gene NameT cell receptor alpha locus, T cell receptor beta locus
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
ClonalityMonoclonal
TargetTCR alpha/beta

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Aberrant Activation of the STING-TBK1 Pathway in γδ T Cells Regulates Immune Responses in Oral Lichen PlanusBiomedicinesMarch 20, 2023Shan Huang, Ya-Qin Tan, Gang ZhouBioLegend) in combination with anti-TCR γδ (PE, BioLegend) or anti-TCR αβ (PE, BioLegend, Catalog #306708), anti-CD69 (PE-Cy7, BioLegend, Catalog #310912), anti-HLA-DR (APC, BD Pharmingen™), anti-TLR4 (BV421,

(2) YIV-906 enhances nuclear factor of activated T-cells (NFAT) activity of T cells and promotes immune checkpoint blockade antibody action and CAR T-cell activityFrontiers in pharmacologyJanuary 1, 2022Lam W, Hu R, Liu SH, Cheng P, Cheng YC.AGGTCGCTGTGTTTGAGCCA, respectively. PE anti-human α/β T Cell Receptor Antibody (BioLegend, Cat#306708) was used to confirm the knockout of TCRαβ using flow cytometry. The targeting sequences for SHP1 (PTPN6)

(3) Numerical optimization of microfluidic vortex shedding for genome editing T cells with Cas9Scientific reportsJune 3, 2021Jarrell JA, Sytsma BJ, Wilson LH, Pan FL, Lau KHWJ, Kirby GTS, Lievano AA, Pawell RS.were quantified by live/dead staining and the following antibodies via flow cytometry: anti-TCRα/β-PE (306708, BioLegend), anti-CD3-AF700 (11-0039-42, ThermoFisher), Sytox Blue Viability Stain (S34857, ThermoFisher),

(4) μ‐Lat: A mouse model to evaluate human immunodeficiency virus eradication strategiesThe FASEB JournalNovember 1, 2020Hannah S. Sperber, Padma Priya Togarrati, Kyle A. Raymond, Mohamed S. Bouzidi, Renata Gilfanova, Alan G. Gutierrez, Marcus O. Muench, Satish K. PillaiCat. #304039, BioLegend), CD4-PE (clone OKT4, Cat. #317410, BioLegend), TCR α/β-PE (clone IP26, Cat. #306708, BioLegend), CD27-PE (clone M-T271, Cat. #356406, BioLegend), CD147-APC (clone HIM6, Cat. #306214, BioLegend),

(5) Single-Cell RNA-Seq Mapping of Human Thymopoiesis Reveals Lineage Specification Trajectories and a Commitment Spectrum in T Cell DevelopmentImmunityJune 16, 2020Le J, Park JE, Ha VL, Luong A, Branciamore S, Rodin AS, Gogoshin G, Li F, Loh YE, Camacho V, et al.APC-Cy7 (clone: SK1),Biolegend,Cat#344714; RRID: AB_2044006 TCRa/b PE (clone: IP26),Biolegend,Cat#306708; RRID: AB_314646 CD56 PE (clone: HCD56),Biolegend,Cat#318306; RRID: AB_604101 CD11c APC (clone: 3.9),Biolegend,Cat#301614;

(6) Impaired lipid biosynthesis hinders anti-tumor efficacy of intratumoral iNKT cellsNature communicationsJanuary 23, 2020Fu S, He K, Tian C, Sun H, Zhu C, Bai S, Liu J, Wu Q, Xie D, Yue T, et al.(Abcam ab3259, 1:100 dilution), PPARγ (Santa cruz sc-7273 FITC, 1:100 dilution), human TCRβ (Biolegend 306708, 1:200 dilution), and human IFN-γ (Biolegend 502528, 1:200 dilution) were used in our experiments. mCD1d-PBS57

(7) Decreased cytotoxic T cells and TCR clonality in organ transplant recipients with squamous cell carcinomaNPJ precision oncologyJanuary 1, 2020Frazzette N, Khodadadi-Jamayran A, Doudican N, Santana A, Felsen D, Pavlick AC, Tsirigos A, Carucci JA.

(8) Reduction of leucocyte cell surface disulfide bonds during immune activation is dynamic as revealed by a quantitative proteomics workflow (SH-IQ)Open biologySeptember 19, 2018Stegmann M, Barclay AN, Metcalfe C.indicated dilutions or concentrations: CD69-APC (Invitrogen, MHCD6905, d1/100), TCR α/β-PE (Biolegend, 306708, d1/100), TCR α/β-biotin (AbD Serotec, MCA1413B, d1/5), streptavidin-FITC (AbD Serotec, STAR2B, d1/200),

(9) Human liver infiltrating γδ T cells are composed of clonally expanded circulating and tissue-resident populationsJournal of hepatologySeptember 1, 2018Hunter S, Willcox CR, Davey MS, Kasatskaya SA, Jeffery HC, Chudakov DM, Oo YH, Willcox BE.

(10) Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC BindingCellJuly 26, 2018Sibener LV, Fernandes RA, Kolawole EM, Carbone CB, Liu F, McAffee D, Birnbaum ME, Yang X, Su LF, Yu W, et al.

(11) Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4⁺ T Cells Permissive for Latent HIV-1 InfectionImmunityOctober 17, 2017Shan L, Deng K, Gao H, Xing S, Capoferri AA, Durand CM, Rabi SA, Laird GM, Kim M, Hosmane NN, et al.

(12) Temporal pharmacokinetic/pharmacodynamic interaction between human CD3ε antigen-targeted monoclonal antibody otelixizumab and CD3ε binding and expression in human peripheral blood mononuclear cell static cultureThe Journal of pharmacology and experimental therapeuticsNovember 1, 2015Page KR, Mezzalana E, MacDonald AJ, Zamuner S, De Nicolao G, van Maurik A.

(13) The DNA methylation signature of human TCRαβ+CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune responseClinical immunology (Orlando, Fla.)January 1, 2015Renauer PA, Coit P, Sawalha AH.

(14) A CD3-specific antibody reduces cytokine production and alters phosphoprotein profiles in intestinal tissues from patients with inflammatory bowel diseaseGastroenterologyJuly 1, 2014Vossenkämper A, Hundsrucker C, Page K, van Maurik A, Sanders TJ, Stagg AJ, Das L, MacDonald TT.

(15) Focal adhesion kinase negatively regulates Lck function downstream of the T cell antigen receptorJournal of immunology (Baltimore, Md. : 1950)December 15, 2013Chapman NM, Connolly SF, Reinl EL, Houtman JC.

(16) Anti-leukemia activity of in vitro-expanded human gamma delta T cells in a xenogeneic Ph+ leukemia modelPloS oneFebruary 3, 2011Siegers GM, Felizardo TC, Mathieson AM, Kosaka Y, Wang XH, Medin JA, Keating A.

(17) Hepcidin messenger RNA expression in human lymphocytesImmunologyJune 1, 2010Pinto JP, Dias V, Zoller H, Porto G, Carmo H, Carvalho F, de Sousa M.

(18) Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activityJournal of virologyMarch 1, 2008Aviva Joseph, Jian Hua Zheng, Antonia Follenzi, Teresa Dilorenzo, Kaori Sango, Jaime Hyman, Ken Chen, Alicja Piechocka-Trocha, Christian Brander, Erik Hooijberg, Dario A Vignali, Bruce D Walker, Harris Goldstein

(19) Simplified, totally enzymatic method for determination of serum triglycerides with a centrifugal analyzerClinical chemistryAugust 1, 1976S H Grossman, E Mollo, G Ertingshausen

(20) Effect of antipsychotic drugs on the firing of dorsal raphe cells. I. Role of adrenergic systemEuropean Journal of PharmacologyJune 17, 1976Dorothy W. Gallager, George K. Aghajanian

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8/22/2016Staining PBMC With Anti-TCR Alpha/Beta PE Adam GuessThis antibody was used to phenotype T cell receptors in human PBMC. It was chosen because it is a commonly used clone, PE is a bright fluorophore, and Biolegend had the best price.

PE anti-human TCR alpha/beta from BioLegend

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PE anti-human TCR alpha/beta from BioLegend

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