Anti-MSH2 (Mismatch Repair Protein) Monoclonal Antibody, Unconjugated, Clone 25D12 PA0057 from Leica Biosystems

Product Specs
ItemAnti-MSH2 (Mismatch Repair Protein) Monoclonal Antibody, Unconjugated, Clone 25D12
CompanyLeica Biosystems
Price Supplier Page View Company Product Page
Catalog NumberPA0057
ReactivityMonoclonal Antibody
CloneClone DO-7
ClonalityMonoclonal Antibody
Quantity7 ml
Conjugate/TagUnconjugated
Targetp53 Protein

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Leica Biosystems

21440 W. Lake Cook Road

Deer Park, Illinois 60010

United States

Phone:
844-534-2262

Company Profile

Website: Leica Biosystems

(1) Li–Fraumeni syndrome in Tunisian carriers with different and rare tumor phenotype: genotype–phenotype correlationBMC Medical GenomicsDecember 1, 2022Hela Sassi, Rym Meddeb, Mohamed Aziz Cherif, Chiraz Nasr, Aouatef Riahi, Samia Hannachi, Neila Belguith, Ridha M’rad36B5—RTU Primary reference PA0387 Leica Bond™) and p53 expression (Clone DO-7—RTU Primary reference PA0057 Leica Bond™). Immunohistochemical analysis was performed in Leica Bond Max automated immunostainer (Leica,

(2) Zebrafish Avatars of rectal cancer patients validate the radiosensitive effect of metforminFrontiers in OncologySeptember 28, 2022Bruna Costa, Laura M. Fernandez, Oriol ParÃ©s, Ricardo Rio-Tinto, InÃªs Santiago, Mireia Castillo-Martin, Amjad Parvaiz, Rita FiorP53 status by immunohistochemistry with the anti-P53 monoclonal antibody (P53-DO7-L-CE, Leica, cat#PA0057), using the Leica Bond Max automated system (Leica Biosystems). A mutant phenotype was considered when

(3) Effect of Chlorhexidine Digluconate in Early Wound Healing of Human Gingival Tissues. A Histological, Immunohistochemical and Biomolecular AnalysisAntibiotics (Basel)October 1, 2021Andrea Pilloni, Simona Ceccarelli, Daniela Bosco, Giulia Gerini, Cinzia Marchese, Lorenzo Marini, Mariana A. RojasNewcastle Ltd., Newcastle Upon Tyne, UK), p53 (BOND™ Ready-to-Use Primary Antibody p53 (DO-7) (Cat# PA0057), Leica Biosystems Newcastle Ltd., Newcastle Upon Tyne, UK). The detection was performed using BOND

(4) Improvement of the Collection, Maintenance, and Analysis of Neoplastic Cells from Urine Specimens with the Use of CytoMatrixMethods and ProtocolsSeptember 10, 2021Simone Minasi, Daniela Bosco, Bernardo Moretti, Felice Giangaspero, Antonio Santoro, Francesca Romana ButtarelliBiosystems, Cat. no.: PA0037)XX.BOND™ Ready-to-Use Primary Antibody p53 (DO-7) (Leica Biosystems, Cat. no.: PA0057)XXI.Vysis FISH Pretreatment Reagent Kit (Abbott Molecular, Thermo Fisher Scientific, Cat. no.: 02J03-032)XXIIUroVysion

(5) The new WHO classification of gastrointestinal neuroendocrine tumors and immunohistochemical expression of somatostatin receptor 2 and 5Experimental and Therapeutic MedicineAugust 13, 2021Oana Popa, Sorina Maria Taban, Stelian Pantea, Andrei Dorel Plopeanu, Robert Alexandru Barna, Marioara Cornianu, Anca-Ariana Pascu, Alis Liliana Carmen Demano. PA0515), synaptophysin (Syn) (clone 27G12, catalog no. PA0299) and p53 (clone DO-7, catalog no. PA0057) antibodies from Leica with ready-to-use (RTU) kits following the manufacturer protocols were used.

(6) Cervical malignant mixed mesonephric tumour: A case report with local recurrence after six-years and next-generation sequencing analysis with particular reference to the ataxia telangiectasia mutated geneExperimental and Therapeutic MedicineFebruary 24, 2021Carla Marani, Iolia Akaev, Chit Cheng Yeoh, Elizabeth Walsh, Siavash RahimiLeica Biosystems; cat. no. PA0346); p53 (ready to use in ER2; mouse mAb clone DO‑7; Leica Biosystems; cat. no. PA0057) and Ki67 (ready to use in ER2; mouse mAb clone MM1; Leica Biosystems; cat. no. PA0230). A total of 20

(7) Evaluating the efficacy of enzalutamide and the development of resistance in a preclinical mouse model of type-I endometrial carcinomaNeoplasia (New York, N.Y.)October 1, 2020Koivisto CS, Parrish M, Bonala SB, Ngoi S, Torres A, Gallagher J, Sanchez-Hodge R, Zeinner V, Nahhas GJ, Liu B, et al.Receptor,Thermo,RM-9102-SO,1:20,CC1 (Tris-EDTA) Estrogen Receptor alpha,Abcam,AB32063,1:2000,Citrate p53,Leica,PA0057,,EDTA Glucocorticoid Receptor,Cell Signaling,12401,1:400,Citrate Antibodies for immunohistochemistry.

(8) Metastatic Melanoma Patient–Derived Xenografts Respond to MDM2 Inhibition as a Single Agent or in Combination with BRAF/MEK InhibitionClinical Cancer ResearchJuly 15, 2020Rebecca L. Shattuck-Brandt et al.software available with the Leica SCN400 Slide Scanner. The antibodies used were as follows: anti-p53 (PA0057, Leica Biosystems, Newcastle, United Kingdom) for 30 minutes; anti-MelanA (PA0233, Leica, Buffalo Grove,

(9) High-grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication-a comprehensive clinical, radiographic, pathologic, and genomic analysisBrain pathology (Zurich, Switzerland)January 1, 2020Ferris SP, Velazquez Vega J, Aboian M, Lee JC, Van Ziffle J, Onodera C, Grenert JP, Saunders T, Chen YY, Banerjee A, et al.(Santa Cruz Biotechnology, cat# sc-514576, clone C-10, 1:200 dilution, 30 min incubation); p53 (Leica, cat# PA0057, clone DO-7, undiluted, 15 min incubation); Ki67 (Dako, cat# GA626, clone MIB1, 1:50 dilution, 30 min

(10) A novel patient-derived orthotopic xenograft model of esophageal adenocarcinoma provides a platform for translational discoveriesDisease Models & MechanismsDecember 1, 2019Omkara Lakshmi Veeranki et al.H&E, CD31 (#77699; CST, Denvers, MA, USA), Her2/neu (#790-2991; Roche, Santa Clara, CA, USA), p53 (PA0057; Leica Microsystems, Buffalo Grove, IL, USA), p16 (#705-4713; Roche, Santa Clara, CA, USA), EGFR (MAB13265;

(11) Differentiated Vulvar Intraepithelial Neoplasia Associated with Intraepithelial Neoplastic SpreadBiomedical Journal of Scientific & Technical ResearchMay 29, 2019KT MaiWetzlar, Germany) for p16 (dilution 1:500, catalogue SC-56330, p53 (dilution: ready to use, catalogue: PA0057, Leica). Tissue sections were subject to epitope retrieval using the Bond epitope retrieval solution

(12) Interaction of renin–angiotensin system and adenosine monophosphate–activated protein kinase signaling pathway in renal carcinogenesis of uninephrectomized ratsTumor BiologyMay 2, 2017Ke-Ke Yang, Yi Sui, Hui-Rong Zhou, Hai-Lu Zhaowere then stained with anti-Ki67 (dilution: 1:400; PA0230; Leica), anti–mutant p53 (dilution: 1:400; PA0057; Leica), anti-phospho-AMPKα (dilution: 1:200; SAB4502329; Sigma-Aldrich, Inc.), and anti-phosphoACC

(13) Genetically engineered rat gliomas: PDGF-driven tumor initiation and progression in tv-a transgenic rats recreate key features of human brain cancerPloS oneJanuary 1, 2017Connolly NP, Stokum JA, Schneider CS, Ozawa T, Xu S, Galisteo R, Castellani RJ, Kim AJ, Simard JM, Winkles JA, et al.of California, San Francisco), Ki-67 (1:100; 275R-18, Sigma-Aldrich, Saint Louis, MO), p53 (1:300; PA0057, Leica Microsystems), glial fibrillary acid protein (GFAP) (1:200; PA0026, Leica Microsystems), oligodendrocyte

(14) High p53 protein expression in therapy-related myeloid neoplasms is associated with adverse karyotype and poor outcomeModern pathology : an official journal of the United States and Canadian Academy of Pathology, IncApril 1, 2015Cleven AH, Nardi V, Ok CY, Goswami M, Dal Cin P, Zheng Z, Iafrate AJ, Abdul Hamid MA, Wang SA, Hasserjian RP.oven. Paraffin-embedded tissues sections (3 microns) were stained with p53 monoclonal antibody DO-7 (PA0057 Ready-to-use, Leica Biosystems, Newcastle, UK) in a Leica Bond-III immunostainer according to the manufacturer’s instructions.

(15) Hobnail Variant of Papillary Thyroid Carcinoma: An Institutional Case Series and Molecular ProfileThyroidJune 1, 2014Carrie C. Lubitz, Konstantinos P. Economopoulos, Amanda C. Pawlak, Kerry Lynch, Dora Dias-Santagata, William C. Faquin, Peter M. Sadow6, 30 min); b-catenin (Leica RTU cat# PA0083 clone 17C2 ER1 pH 6, 30 min); and p53 (Leica RTU cat# PA0057 clone DO7 ER2, EDTA pH 9, 20 min). Statistical analysis Continuous outcomes were expressed as mean

(16) A Pathogenic Mosaic TP53 Mutation in Two Germ Layers Detected by Next Generation SequencingPLoS ONEMay 8, 2014Sam Behjati et al.of FFPE tissue were stained with mouse anti-human monoclonal antibody (clone DO-7 from Leica, cat# PA0057) using the Leica BOND-MAX automated system. Antigen retrieval was performed using the BOND-MAX heat

(17) A phase I trial of aminolevulinic acid-photodynamic therapy for treatment of oral leukoplakiaOral OncologySeptember 1, 2013Stuart J. Wong et al.following antibodies were used for marker detection: For p53, mouse antihuman monoclonal Ab (DO-7), (PA0057; Leica Biosystems, United Kingdom), ready to use (RTU) antibody optimized for Bond Leica detection system;

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Anti-MSH2 (Mismatch Repair Protein) Monoclonal Antibody, Unconjugated, Clone 25D12 from Leica Biosystems

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Leica Biosystems

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Anti-MSH2 (Mismatch Repair Protein) Monoclonal Antibody, Unconjugated, Clone 25D12 from Leica Biosystems

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