Anti-Lambda Light Chain Monoclonal Antibody, Unconjugated NCL-L-MLH1 from Leica Biosystems

Product Specs
ItemAnti-Lambda Light Chain Monoclonal Antibody, Unconjugated
CompanyLeica Biosystems
Price Supplier Page View Company Product Page
Catalog NumberNCL-L-MLH1
Conjugate/TagUnconjugated
Quantity1 ml, 0.1 ml
TargetMismatch Repair Protein (MLH1)
ClonalityMonoclonal Antibody

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Leica Biosystems

21440 W. Lake Cook Road

Deer Park, Illinois 60010

United States

Phone:
844-534-2262

Company Profile

Website: Leica Biosystems

(1) Mismatch repair markers in preoperative and operative endometrial cancer samples; expression concordance and prognostic valueBritish Journal of CancerFebruary 16, 2023Hege F. Berg, Hilde Engerud, Madeleine Myrvold, Hilde E. Lien, Marta Espevold Hjelmeland, Mari K. Halle, Kathrine Woie, Erling A. Hoivik, Ingfrid S. Haldorsen, Olav Vintermyr, et al.Germany) or incubated for 30 min at room temperature with anti-MLH1 monoclonal mouse antibody (1:100; NCL-L-MLH1; NovocastraTM, Leica Biosystems Newcastle, UK) or anti-MSH2 monoclonal mouse antibody (1:50; NCL-l-MSH2–612;

(2) Profiling chromosomalâ€level variations in gastric malignanciesCancer ScienceSeptember 9, 2022Tetsuya Negoto, Minji Jo, Izuma Nakayama, Motohiro Morioka, Kengo Takeuchi, Hiroshi Kawachi, Toru Hirotalymphocytes were used as an internal control for the evaluation. The following Abs were used: MLH1 (ES05, NCL‐L‐MLH1; Leica), MSH2 (G219‐1129, 556,349; BD Biosciences), MSH6 (EPR3945, GTX62383; GeneTex), PMS2 (A16‐4,

(3) Undifferentiated Sarcomas Develop Through Distinct Evolutionary PathwaysSSRN Electronic JournalApril 1, 2022Christopher D. Steele et al.detection with DAB and counterstaining with hematoxylin. MLH1 MLH1 (Leica, mouse monoclonal ES05, cat. NCL-L-MLH1): diluted 1/200. Epitope retrieval: ER2 (high pH), 40 minutes, 99 C. MSH2 MSH2 (Agilent Technologies,

(4) WRN Germline Mutation Is the Likely Inherited Etiology of Various Cancer Types in One Iranian FamilyFrontiers in OncologyJune 7, 2021Mahnaz Norouzi, Mohammad Shafiei, Zeinab Abdollahi, Paniz Miar, Hamid Galehdari, Mohammad Hasan Emami, Mehrdad Zeinalian, Mohammad Amin TabatabaiefarProduct Code (PC): NCL-MSH2; at 1/80 dilution), MLH1 (Leica Biosystems: Novocastra, UK, Liquid, PC: NCL-L-MLH1; at 1/100 dilution), MSH6 (Leica Biosystems: Novocastra, UK, Liquid, PC: NCL-L-MSH6; at 1/100 dilution),

(5) Double somatic mismatch repair gene pathogenic variants as common as Lynch syndrome among endometrial cancer patientsGynecologic OncologyJanuary 1, 2021Heather Hampel et al.routine clinical care for all but four patients. Antibodies included MLH-1 Clone: Leica ES05 (Mouse: NCL-L-MLH1), MSH-2 Clone: Calbiochem FE11 (Mouse: NA27), MSH-6 Clone: Epitomics EP49 (Rabbit: AC-0047), PMS-2 Clone:

(6) The efficacy of DNA mismatch repair enzyme immunohistochemistry as a screening test for hypermutated gliomasActa Neuropathologica CommunicationsDecember 1, 2020Matthew McCord, Alicia Steffens, Rodrigo Javier, Kwok-Ling Kam, Kathleen McCortney, Craig Horbinskiantibodies, including Msh2 (Cell Marque G219–1129, 1:700), Msh6 (Cell Marque 44 (287 M-15), 1:100), Mlh1 (Leica NCLL-MLH1, 1:100), and Pms2 (Cell Marque MRQ-28 (288 M-15), 1:50). Formalin-fixed, paraffin-embedded 4 μm thick

(7) The impact of mismatch repair status to the preoperative staging of colon cancer: implications for clinical managementColorectal CancerJuly 1, 2020Emilie Erbs, Søren Rafael Rafaelsen, Jan Lindebjerg, Lars Henrik Jensen, Torben Frøstrup Hansenwere used against MLH1 (Novocastra, Leica, Wetzlar, Germany, clone ES05, dilution 1:100, product code NCL-L-MLH1), MSH2 (Novocastra, Leica, Wetzlar, Germany, clone 25D12, dilution 1:100, product code NCL-L-MSH2),

(8) Rapid and complete paraffin removal from human tissue sections delivers enhanced Raman spectroscopic and histopathological analysis† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9an01030kThe AnalystFebruary 17, 2020Riana Gaifulina, Daren J. Caruana, Dahmane Oukrif, Naomi J. Guppy, Siân Culley, Robert Brown, Ian Bell, Manuel Rodriguez-Justo, Katherine Lau, Geraint M. H. Thomaswas carried out in a pH 9 Tris-EDTA buffer using a pressure cooker. MLH1 (Monoclonal Mouse Antibody NCL-L-MLH1, Leica clone ES05) was diluted down to 1 : 200 in TBS Tween, whilst MSH6 (Monoclonal Rabbit Anti-Human

(9) Mismatch repair protein loss in breast cancer: clinicopathological associations in a large British Columbia cohortBreast Cancer Research and TreatmentJanuary 1, 2020Angela S. Cheng, Samuel C. Y. Leung, Dongxia Gao, Samantha Burugu, Meenakshi Anurag, Matthew J. Ellis, Torsten O. Nielsenmonoclonal EP49; Epitomics: AC-0047, 1:50 dilution), MLH1 (mouse monoclonal ES05; Leica Biosystems: NCL-L-MLH1, 1:50 dilution), or PMS2 (rabbit monoclonal EP51; Epitomics: AC-0049, 1:20 dilution). Tonsil tissues,

(10) Granular dot-like staining with MLH1 immunohistochemistry is a clone-dependent artefactPathology, research and practiceJanuary 1, 2020Dasgupta S, Ewing-Graham PC, Groenendijk FH, Stam O, Biermann KE, Doukas M, Dubbink HJ, van Velthuysen MF, Dinjens WNM, Van Bockstal MR.staining pattern in the nuclei of the tumor cells was noted. We repeated MLH1IHC using the ES05-clone (NCL-L-MLH1, Leica Biosystems Newcastle, Newcastle Upon Tyne, UK). The tumour showed no MLH1 expression (Fig. 1).

(11) Programmed Death Ligand-1 expression in stage II colon cancer - experiences from a nationwide populationbased cohortBMC CancerDecember 1, 2019Ann C. Eriksen, Flemming B. Sørensen, Jan Lindebjerg, Henrik Hager, René dePont Christensen, Sanne Kjær-Frifeldt, Torben F. Hansenmonoclonal mouse antibody against MLH1 (Novocastra, Leica, Germany, clone ES05, dilution 1:100, product code NCL-L-MLH1), MSH2 (Novocastra, Leica, clone 25D12, dilution 1:100, product code NCL-L-MSH2), MSH6 (BD Transduction

(12) Clinical characteristics of patients with colorectal cancer with double somatic mismatch repair mutations compared with Lynch syndromeJournal of Medical GeneticsJuly 1, 2019Rachel Pearlman, Sigurdis Haraldsdottir, Albert de la Chapelle, Jon G. Jonasson, Sandya Liyanarachchi, Wendy L. Frankel, Thorunn Rafnar, Kari Stefansson, Colin C. Pritchard, Heather Hampelthe MSI and two-stain IHC results were discordant. Antibodies included MLH-1 Clone: Leica ES05 (Mouse: NCL-L-MLH1), MSH-2 Clone: Calbiochem FE11 (Mouse: NA27), MSH-6 J Med Genet. Author manuscript; available in PMC

(13) Enrichment of CLDN18 ‐ ARHGAP fusion gene in gastric cancers in young adultsCancer ScienceApril 4, 2019Izuma Nakayama et al.MLH1, MSH2, MSH6, and PMS2 was examined by IHC, in which the following Abs were used: MLH1 (ES05) (NCL‐L‐MLH1; Leica), MSH2 (G219‐1129) (556349; BD Biosciences, NJ, USA), MSH6 (EPR3945) (GTX62383; GeneTex, CA,

(14) Undifferentiated Sarcomas Develop through Distinct Evolutionary PathwaysCancer CellMarch 18, 2019Christopher D. Steele et al.detection with DAB and counterstaining with hematoxylin. MLH1 MLH1 (Leica, mouse monoclonal ES05, cat. NCL-L-MLH1): diluted 1/200. Epitope retrieval: ER2 (high pH), 40 minutes, 99°C. MSH2 MSH2 (Agilent Technologies,

(15) Prognostic impact of CDX2 in stage II colon cancer: results from two nationwide cohortsBritish Journal of CancerNovember 1, 2018Torben Frøstrup Hansen, Sanne Kjær-Frifeldt, Ann Christina Eriksen, Jan Lindebjerg, Lars Henrik Jensen, Flemming Brandt Sørensen, Anders Jakobsenmouse antibodies: MLH1 (Novocastra, Leica, (Wetzlar) Germany, clone ES05, dilution 1:100, product code NCL-L-MLH1); MSH2 (Novocastra, Leica, clone 25D12, dilution 1:100, product code NCL-L-MSH2); MSH6 (BD Transduction

(16) Studies on selected molecular factors in endometrial cancersAdvances in clinical and experimental medicine : official organ Wroclaw Medical UniversityOctober 1, 2018Markowska A, Szarszewska M, Żurawski J, Sajdak S, Knapp P, Gryboś A, Olejek A, Bednarek W, Roszak A, Jóźwik M, et al.(Santa Cruz Biotechnology, Santa Cruz, USA sc-10, clone C-12), MLH1 (Leica NCL-L, Buffalo Grove, USA NCL-L-MLH1, clone ES05), MSH2 (Invitrogen, Carlsbad, USA 33-7900, clone FE11), PgR (Dako, Santa Clara, USA M3569,

(17) The prognostic value of tumour stroma ratio and tumour budding in stage II colon cancer. A nationwide population-based studyInternational Journal of Colorectal DiseaseAugust 1, 2018Ann Christina Eriksen, Flemming B. Sørensen, Jan Lindebjerg, Henrik Hager, René dePont Christensen, Sanne Kjær-Frifeldt, Torben F. Hansenmouse antibodies: MLH1 (Novocastra, Leica, (Wetzlar) Germany, clone ES05, dilution 1:100, product code NCL-L-MLH1), MSH2 (Novocastra, Leica, clone 25D12, dilution 1:100, product code NCL-L-MSH2), MSH6 (BD Transduction

(18) The Prognostic Value of Tumor-Infiltrating lymphocytes in Stage II Colon Cancer. A Nationwide Population-Based Study1Translational OncologyJune 22, 2018Ann C. Eriksen, Flemming B. Sørensen, Jan Lindebjerg, Henrik Hager, René dePont Christensen, Sanne Kjær-Frifeldt, Torben F. Hansenmonoclonal mouse antibody against MLH1 (Novocastra, Leica, Germany, clone ES05, dilution 1:100, product code NCL-L-MLH1), MSH2 (Novocastra, Leica, clone 25D12, dilution 1:100, product code NCL-L-MSH2), MSH6 (BD Transduction

(19) Prognostic impact of CDX2 in stage II colon cancer: Results from two nationwide cohortsJournal of Clinical OncologyMay 20, 2018Torben Hansen, Sanne Kjaer-Frifeldt, Ann Christina Eriksen, Jan Lindebjerg, Lars Henrik Jensen, Flemming Brandt Soerensen, Anders Kristian Moeller Jakobsenmonoclonal mouse antibodies: MLH1 (Novocastra, Leica, (Wetzlar) Germany, clone ES05, dilution 1:100, product code NCL-L-MLH1); MSH2 (Novocastra, Leica, clone 25D12, dilution 1:100, product code NCLL-MSH2); MSH6 (BD Transduction

(20) Programmed cell death ligand 1 cut-point is associated with reduced disease specific survival in resected pancreatic ductal adenocarcinomaBMC CancerDecember 1, 2017Basile Tessier-Cloutier, Steve E. Kalloger, Mohammad Al-Kandari, Katy Milne, Dongxia Gao, Brad H. Nelson, Daniel J. Renouf, Brandon S. Sheffield, David F. Schaeffer[19]. For MMR stains, slides were incubated with MLH1 (mouse monoclonal antibody, 1:50 dilution, cat#: NCL-L- MLH1, clone ID:ES05; Leica Microsystems, New- castle, UK), MSH2 (mouse monoclonal antibody, 1:1000 dilution,

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Anti-Lambda Light Chain Monoclonal Antibody, Unconjugated from Leica Biosystems

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Anti-Lambda Light Chain Monoclonal Antibody, Unconjugated from Leica Biosystems

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