Anti-Pax-5 Monoclonal Antibody, Unconjugated, Clone 1EW PA0553 from Leica Biosystems

Product Specs
ItemAnti-Pax-5 Monoclonal Antibody, Unconjugated, Clone 1EW
CompanyLeica Biosystems
Price Supplier Page View Company Product Page
Catalog NumberPA0553
Conjugate/TagUnconjugated
CloneClone LN10
Quantity7 ml
ReactivityMonoclonal Antibody
ClonalityMonoclonal Antibody
TargetCD3

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Leica Biosystems

21440 W. Lake Cook Road

Deer Park, Illinois 60010

United States

Phone:
844-534-2262

Company Profile

Website: Leica Biosystems

(1) Comprehensive Single-Cell Immune Profiling Defines the Patient Multiple Myeloma Microenvironment Following Oncolytic Virus Therapy in a Phase Ib TrialClinical Cancer ResearchDecember 15, 2023Steffan T. Nawrocki, Julian Olea, Claudia Villa Celi, Homa Dadrastoussi, Kaijin Wu, Denice Tsao-Wei, Anthony Colombo, Matthew Coffey, Eduardo Fernandez Hernandez, Xuelian Chen, et al.performed by USC Pathology using antibodies against CD3 (Leica Biosystems, Deer Park, IL; catalog no. PA0553, RRID:AB_10554601) and CD138 (Leica Biosystems, catalog no. PA0088, RRID:AB_10555989). The viral RNA

(2) Magnetic resonance imaging findings of the primitive neuroectodermal tumour in lumbosacral spinal cord in a catVeterinary Medicine and ScienceNovember 1, 2023Takamasa Itoi, Kenji Kutara, Ikki Mitsui, Natsuki Akashi, Teppei Kanda, Keisuke Sugimoto, Yuki Shimizu, Kazuaki YamazoeAE1/AE3",RTU,Leica,PA0094 Porcine vimentin,Mouse,"Monoclonal, V9",1:600,DAKO,M0725 Human CD3,Mouse,"Monoclonal, LN10",RTU,Leica,PA0553 Human CD20,Rabbit,Polyclonal,1:200,Invitrogen,PA5‐16701 Human CD45,Mouse,"Monoclonal, 2B11 + PD7/26",1:300,DAKO,M0701 Human

(3) PSGL-1 Blockade Induces Classical Activation of Human Tumor-associated MacrophagesCancer Research CommunicationsOctober 26, 2023Kevin Kauffman, Denise Manfra, Dominika Nowakowska, Mohammad Zafari, Phuong A. Nguyen, Ryan Phennicie, Elisabeth H. Vollmann, Brian O'Nuallain, Sara Basinski, Veronica Komoroski, et al.into a multiplex IHC panel for tumor microarray (TMA) screening. For CD3, clone LN10 was used (Leica, PA0553), for CD163 - clone 10D6 (Abcam, ab74604), for CD68 - clone KPI (Dako, M0814). PSGL-1 IHC staining protocols

(4) Multi-omic approach identifies hypoxic tumor-associated myeloid cells that drive immunobiology of high-risk pediatric ependymomaiScienceSeptember 15, 2023Griesinger AM, Riemondy K, Eswaran N, Donson AM, Willard N, Prince EW, Paine SML, Bowes G, Rheaume J, Chapman RJ, et al.RRID:AB_2216680 HLA-DR,Abcam,Ab20181; RRID AB_445401 CD206,Novus,NBP2-52927; RRID NA CD64,Abcam,Ab140779; RRID NA CD3,Leica,PA0553; RRID NA CD14,Abcam,Ab183322; RRID AB_2909463 DAPI,Akoya,FP1490; RRID NA HRP-conjugated secondary

(5) Heterogeneous distribution pattern of CD3+ tumor-infiltrated lymphocytes (TILs) and high combined positive score (CPS) favored the prognosis of resected early stage small-cell lung cancerTranslational OncologyAugust 1, 2023Liang Zhu, Guoping Cheng, Meijuan Wu, Ming Chen, Ying Jinagainst human CD8 (Clone 4B11, Cat# PA0183), CD4 (Clone 4B12, Cat# PA0427) and CD3 (Clone LN10, Cat# PA0553) were purchased from Leica (Leica Biosystems, Newcastle Upon Tyne, UK), visualization of the antibody

(6) Possible role for IL-40 and IL-40-producing cells in the lymphocytic infiltrated salivary glands of patients with primary Sjögren’s syndromeRMD OpenMay 3, 2023Giuliana Guggino, Chiara Rizzo, Leila Mohammadnezhad, Marianna Lo Pizzo, Vincenzo Luca Lentini, Diana Di Liberto, Lidia La Barbera, Stefania Raimondo, Mojtaba Shekarkar Azgomi, Ornella Urzì, et al.in the protocol previously described.14 The monoclonal antibodies used were: mouse anti-human CD3 (PA0553, Leica Bond, Germany), mouse anti-human CD19 (M7296, Dako) and mouse anti-human CD68 (M0876, Dako),

(7) Syndecan-1 as an immunogene in Triple-negative breast cancer: regulation tumor-infiltrating lymphocyte in the tumor microenviroment and EMT by TGFb1/Smad pathwayCancer cell internationalApril 17, 2023Zhong Y, Li F, Zhang S, Yang Z, Ren X, Cao X, Xu Y, Guo D, Zhou Y, Mao F, et al.Pathologists and Proposal [31]. All TMA were stained for SDC1 (prediluted, Jinqiaoyatu, Beijing, China), CD3 (PA0553, prediluted; Leica Microsystems, Shanghai, China), CD4 (PA0427, prediluted; Leica Microsystems), CD8

(8) Metastatic pancreatic neuroendocrine tumors feature elevated T cell infiltrationJCI insightDecember 8, 2022Greenberg J, Limberg J, Verma A, Kim D, Chen X, Lee YJ, Moore MD, Ullmann TM, Thiesmeyer JW, Loewenstein Z, et al.blocks were cut at 5 μm–thick intervals, and consecutive slides were stained for H&E, CD3 (catalog PA0553, clone LN10, Leica), CD8 (catalog PA0183/clone 4B11, Leica), CCL5 (catalog ab9679, Abcam) at the Translational

(9) Interplay between Immune Cell Infiltration and Tumor Histological Subtype: A Case of Adrenocortical CancerCancers (Basel)October 28, 2022Apollinariya V. Bogolyubova, Nano V. Pachuashvili, Arina V. Tkachuk, Natalia G. Mokrysheva, Liliya S. UrusovaIII IHC staining system using Leica reagents and protocols. Antibodies to CD45 (PA0042, Leica), CD3 (PA0553, Leica), CD4 (PA0427, Leica), CD8 (PA0183, Leica), and CD68 (PA0273, Leica) were used. All histological

(10) Molecular Signature of Tumor-Associated High Endothelial Venules That Can Predict Breast Cancer SurvivalCancer immunology researchApril 1, 2022Sawada J, Hiraoka N, Qi R, Jiang L, Fournier-Goss AE, Yoshida M, Kawashima H, Komatsu M.were used to detect immune cells: CD8 (4B11, Leica PA0183), CD20 (L26, Leica PA0200), CD3 (LN10, Leica PA0553), Foxp3 (Novus Biological, NB100-39002), and DC-LAMP (1010E1.01, Novus DDX0191P-100). For staining HEVs,

(11) Insulin expression and C-peptide in type 1 diabetes subjects implanted with stem cell-derived pancreatic endoderm cells in an encapsulation deviceCell reports. MedicineDecember 21, 2021Shapiro AMJ, Thompson D, Donner TW, Bellin MD, Hsueh W, Pettus J, Wilensky J, Daniels M, Wang RM, Brandon EP, et al.antibodies to detect alpha smooth muscle actin (ACTA2, Abcam ab125044); CD22 (Leica PA0249); CD3 (Leica PA0553); CD34 (Leica PA0212); CDX2 (Abcam ab76541); chromogranin A (Abcam ab68271); FOXA2 (Abcam ab108422);

(12) Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancerNature CommunicationsNovember 17, 2021Ming Chen, Runzhe Chen, Ying Jin, Jun Li, Xin Hu, Jiexin Zhang, Junya Fujimoto, Shawna M. Hubert, Carl M. Gay, Bo Zhu, et al.anti-CD3 monoclonal antibody (BOND™ Ready-to-Use Primary Antibody CD3 (LN10) (no dilution), Cat No. PA0553, Leica Biosystems, Newcastle Upon Tyne, UK; https://shop.leicabiosystems.com/zh-cn/ihc-ish/ihc-primary-antibodies/pid-cd3)

(13) Phase 1 trial of nelfinavir added to standard cisplatin chemotherapy with concurrent pelvic radiation for locally advanced cervical cancerCancerJuly 1, 2021Arlene E. Garcia‐Soto et al.catalog no. 4858L), p16INK4A (Roche Diagnostics; catalog no. 9517), CD3 (Leica Microsystems; catalog no. PA0553), CD8 (Agilent Dako; catalog no. M7103), and hypoxia‐inducible factor α (HIF1α) (Biocare Medical; catalog

(14) Susceptibility-weighted imaging reveals cerebral microvascular injury in severe COVID-19Journal of the Neurological SciencesFebruary 1, 2021John Conklin et al.stainer, with mouse monoclonal antibodies directed against neurofilament (Dako M0762, 1:3200), CD3 (Leica PA0553, used as supplied), CD163 (Leica Cat #PA 0090, used as supplied) and CD68 (Biocare Cat # IP-033-AA,

(15) Association of cancer progression with elevated expression of programmed cell death protein 1 ligand 1 by upper tract urothelial carcinoma and increased tumor-infiltrating lymphocyte densityCancer Immunology, ImmunotherapyMay 1, 2020Akinori Nukui et al.detected on the eosin-stained slides in this study were classified as TILs, using antibody against CD3 (PA0553, Leica Biosystems Newcastle Ltd, Newcastle, UK), CD4 (NCL-CD4-1F6, Leica Biosystems Newcastle Ltd, Newcastle,

(16) Tropism, pathology, and transmission of equine parvovirus-hepatitisEmerging Microbes & InfectionsMarch 21, 2020Joy Ellen Tomlinson, Mason Jager, Alyssa Struzyna, Melissa Laverack, Lisa Ann Fortier, Edward Dubovi, Lane D. Foil, Peter D. Burbelo, Thomas J. Divers, Gerlinde R. Van de Walle(HE), Masson’s trichrome, reticulin, and antibodies against the T cell marker CD3 (Leica, catalogue #PA0553, mouse monoclonal anti-human clone LN10), the macrophage marker Iba1 (Wako Pure Chemical Industries,

(17) Distinct Host–Mycobacterial Pathogen Interactions between Resistant Adult and Tolerant Tadpole Life Stages of Xenopus laevisThe Journal of ImmunologyNovember 15, 2019Kun Hyoe Rhoo, Eva-Stina Edholm, María J. Forzán, Adil Khan, Anthony W. Waddle, Martin S. Pavelka, Jacques Robertmm2 of liver tissue. Immunohistochemical (IHC) staining with anti-CD3 receptor antibody (Leica Cat # PA0553; [19]) was performed using an automated platform to identify conventional T cells (Bond-Max IHC/ISH

(18) Genomic Signatures Predict the Immunogenicity of BRCA-Deficient Breast CancerClinical Cancer ResearchJuly 15, 2019Adam A. Kraya et al.Immunohistochemistry was performed using mouse monoclonal antibodies for CD3 (Leica Biosystems; Wetzlar, Germany; cat. PA0553), CD8 (Dako; Glastro, Denmark; cat. M7103), CD20 (Dako; Glastro, Denmark; cat. M0755), CD45 (Dako, Glastro,

(19) Characterization of a Vesivirus Associated with an Outbreak of Acute Hemorrhagic Gastroenteritis in Domestic DogsJournal of clinical microbiologyMay 1, 2018Renshaw RW, Griffing J, Weisman J, Crofton LM, Laverack MA, Poston RP, Duhamel GE, Dubovi EJ.Leica Biosystems Newcastle, Ltd.); T lymphocytes were labeled with the mouse monoclonal IgG2a, clone LN10 (PA0553; Leica Biosystems Newcastle, Ltd.), anti-human T cell antigen receptor complex CD3; tissue histiocytes,

(20) Activating MAPK1 (ERK2) mutation in an aggressive case of disseminated juvenile xanthogranulomaOncotargetJuly 11, 2017Chakraborty R, Hampton OA, Abhyankar H, Zinn DJ, Grimes A, Skull B, Eckstein O, Mahmood N, Wheeler DA, Lopez-Terrada D, et al.Grove, IL, as it is), CD207 (NCLLANGERIN-U, Leica Biosystems, Buffalo Grove, IL, 1:100 dilution), CD1A (PA0553, Leica Biosystems, Buffalo Grove, IL, as it is), Factor XIII (PA0449, Leica Biosystems, Buffalo Grove,

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Anti-Pax-5 Monoclonal Antibody, Unconjugated, Clone 1EW from Leica Biosystems

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Anti-Pax-5 Monoclonal Antibody, Unconjugated, Clone 1EW from Leica Biosystems

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