Fig 1: L-siRNAs did not increase the interleukins levels evaluated. (a) L-1ß. (b) TNF-a. (c) IFN-?. (d) IL-6. The stimuli are given by: LPS (Lipopolysaccharide 100 ng/mL), RPMI 1640, liposomes-siRNA (L-siRNA1, L-siRNA2, L-siRNA3.1, L-siRNA4. As negative control, blood was used without stimulus (blood). Data are expressed as Mean + SEM of the three independent assays in triplicate. The measurement is given by the intensity in grayscale in an equivalent area in all the samples (911 square pixels). ** p < 0.001 *** p < 0.0001 **** p < 0.00001. The measurement was performed with Fiji and was represented as Log10 through GraphPad Prism 9.