Anti-Monocarboxylic acid transporter 1 antibody ab90582 from Abcam

Product Specs
ItemAnti-Monocarboxylic acid transporter 1 antibody
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab90582
HostMouse, Nude mouse
Conjugate/TagUnconjugated
ClonalityPolyclonal
Quantity50 UG
IsotypeIgG
ApplicationsImmunocytochemistry/ Immunofluorescence, Western blot
Antibody TypePrimary
Concentration0.5 mg/ml
Gene NameSLC16A1
ReactivityHuman
TargetMonocarboxylic acid transporter 1

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+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) Distribution of Monocarboxylate Transporters in Brain and Choroid Plexus EpitheliumPharmaceuticsJuly 31, 2023Ueno M, Chiba Y, Murakami R, Miyai Y, Matsumoto K, Wakamatsu K, Takebayashi G, Uemura N, Yanase K.of the cytoplasm of CPEs in autopsied diseased human brains [43]. Immunoreactivity for MCT1 (Abcam, ab90582) is confirmed to be expressed in endothelial cells, reactive astrocytes, and on the apical side of the

(2) Corneal Edema in Inducible Slc4a11 Knockout Is Initiated by Mitochondrial Superoxide Induced Src Kinase ActivationCellsJune 1, 2023Diego G. Ogando, Edward T. Kim, Shimin Li, Joseph A. Bonanno(Protein Simple, San Jose, CA, USA). Antibodies were added at the following dilutions: MCT1 (Abcam #ab90582) 1:10; MCT2 (Santa Cruz Biotechnologies #sc-166925, Santa Cruz, CA, USA) 1:10; MCT4 (Santa Cruz #sc-376465)

(3) Lactate trafficking inhibition restores sensitivity to proteasome inhibitors and orchestrates immuno‐microenvironment in multiple myelomaCell ProliferationApril 1, 2023Alessandro Barbato, Cesarina Giallongo, Sebastiano Giallongo, Alessandra Romano, Grazia Scandura, Saoca Concetta, Tatiana Zuppelli, Marco Lolicato, Giacomo Lazzarino, Nunziatina Parrinello, et al.phosphate‐buffered saline (PBS) for 5 min and incubated with primary antibodies against human MCT1 (ab90582, Abcam, Mylan, Italy), MCT4 (ab234728, Abcam), and β‐actin (ab181602, Abcam). Next day, after three

(4) Prognostic Value of Monocarboxylate Transporter 1 Overexpression in Cancer: A Systematic ReviewInternational Journal of Molecular SciencesMarch 7, 2023Ana Silva, Mónica Costa Cerqueira, Beatriz Rosa, Catarina Sobral, Filipa Pinto-Ribeiro, Marta Freitas Costa, Fátima Baltazar, Julieta AfonsoSanta Cruz Biotechnology",Dako EnVisionTM FLEX Target Retrieval,I + E,0–2 "Sun et al., 2022 [73]","AB90582, rabbit polyclonal, Abcam",Dako EnVisionTM FLEX Target Retrieval,I,≥0.8 "Zhao et al., 2022 [64]","20139-1-AP,

(5) Upregulation of HMGB1 in tumor-associated macrophages induced by tumor cell-derived lactate further promotes colorectal cancer progressionJournal of Translational MedicineJanuary 28, 2023Xinyi Gao, Shiqi Zhou, Zhaofu Qin, Dechuan Li, Yuping Zhu, Dening Maincubated with anti-HIF-1α (1:1000; ab1; Abcam), anti-PGC1α (1:1000; ab106814; Abcam), anti-MCT1 (1:3000; ab90582; Abcam), anti-MCT4 (1:1000; ab234728; Abcam), anti-CD174 (1:2000; ab235831; Abcam), anti-HMGB1 (1:1000;

(6) Lactate Rewrites the Metabolic Reprogramming of Uveal Melanoma Cells and Induces Quiescence PhenotypeInternational Journal of Molecular SciencesDecember 20, 2022Lucia Longhitano, Sebastiano Giallongo, Laura Orlando, Giuseppe Broggi, Antonio Longo, Andrea Russo, Rosario Caltabiano, Cesarina Giallongo, Ignazio Barbagallo, Michelino Di Rosa, et al.Germany). 4.3. Western Blot Analysis Protein detection was performed by incubating MCT1 (1:1000; AB90582, Abcam, Cambridge, UK) and β-actin (1:1000; anti-mouse, cat. no. 4967S; Cell Signalling Technology,

(7) Cerebral Ischemic Preconditioning Aggravates Death of OligodendrocytesBiomoleculesDecember 14, 2022Teng Guan, Ying Guo, Chengren Li, Ting Zhou, Qiang Yu, Chaoxian Yang, Guohui Zhang, Jiming Kong(Sigma-Aldrich, 05-710, 1:500), rabbit anti-MCT1 (Santa Cruz (Santa Cruz, CA, USA), SC-50325, 1:50; Abcam, ab90582, 1:500), rabbit anti-PDGFRα (Santa Cruz, sc-398206, 1:200), goat anti-MBP (Santa Cruz, sc-13914, 1:5000)

(8) Lactate Induces the Expressions of MCT1 and HCAR1 to Promote Tumor Growth and Progression in GlioblastomaFrontiers in OncologyApril 28, 2022Lucia Longhitano et al.phosphate-buffered saline (PBS) for 5 min and incubated with primary antibodies against MCT1 (1:1,000; AB90582), MCT4 (1:1,000; AB74109), β-catenin (1:500; AB16051), E-cadherin (1:500; AB76055, all from Abcam, Cambridge,

(9) Lactate Rewires Lipid Metabolism and Sustains a Metabolic-Epigenetic Axis in Prostate CancerCancer researchApril 1, 2022Ippolito L, Comito G, Parri M, Iozzo M, Duatti A, Virgilio F, Lorito N, Bacci M, Pardella E, Sandrini G, et al.were stained with PLIN2 (rabbit; HPA016607, RRID:AB_2669403; Merck Millipore, 1:250) and MCT1 (mouse ab90582; RRID:AB_2050317; Abcam, 1:200). Immunohistochemistry was performed using the Leica BOND-MAX™ automated

(10) Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in micePLOS ONEFebruary 3, 2022Chunxing Yang et al.(Sigma,T5168, 1:10000), CNPase (Cell Signaling, #5664s,1:1000), MBP(Abcam,ab62631,1:1000), MCT1(Abcam, ab90582, 1:1000), NFkB-p65 (Cell signaling, #8242, 1:1000), and phosphorylated NFkB-p65 (Cell signaling, #3033,

(11) Prognostic implications of combined high expression of CD47 and MCT1 in breast cancer: a retrospective study during a 10-year periodTranslational Cancer ResearchJanuary 1, 2022Yanting Sun, Shujing Liang, Tong Li, Chujie Peng, Yiting Yang, Yun Lin, Yabin Ma, Chunyan Dongpatients. Immunohistochemical staining and evaluation CD47 (A1838, 1:200 dilutions; ABclonal, Wuhan, China) and MCT1 (ab90582, 1:200 dilutions; Abcam, Cambridge, UK) were measured using immunohistochemical staining as described

(12) Distinct glycolytic pathway regulation in liver, tumour and skeletal muscle of mice with cancer cachexiaCell biochemistry and functionAugust 1, 2021Visavadiya NP, Rossiter HB, Khamoui AV.antibodies against mouse polyclonal to monocarboxylic acid transporter 1 (MCT1, 1: 2500 dilution, cat# ab90582, Abcam Inc.), rabbit polyclonal to glucose transporter 1 (GLUT1, 1:1000 dilution, cat# NB110-39113,

(13) Elevated Lactate by High-Intensity Interval Training Regulates the Hippocampal BDNF Expression and the Mitochondrial Quality Control SystemFrontiers in physiologyJanuary 1, 2021Hu J, Cai M, Shang Q, Li Z, Feng Y, Liu B, Xue X, Lou S.biogenesis NRF1 68 CST NRF2 97 CST TFAM 28 Abcam MCT1 54 MCT4 49 Proteintech B-TUBULIN 50 Proteintech 10068-1-AP 1:2000 monocarboxylic acid transporter Abcam NBP1-04676 1:1000 46743 1:1000 12721 1:1000 ab131607 1:2000 ab90582 1:1000 22787-1-AP 1:1000 COX5b, and Atp5a1. Details of the Primers used are provided below (Table

(14) The NMDA receptor regulates competition of epithelial cells in the Drosophila wingNature CommunicationsDecember 1, 2020Agnes R. Banreti, Pascal MeierUSA), PHA-555 (Phalloidin-555, A34055, Invitrogen/Molecular probes), mouse polyclonal anti-MCT1 (1:100, ab90582, Abcam), rabbit polyclonal anti-Myc (1:100, d1-717, sc-28207 Santa Cruz Biotechnology), rabbit polyclonal

(15) Cell-to-cell lactate shuttle operates in heart and is important in age-related heart failureAgingFebruary 8, 2020Gizak A, McCubrey JA, Rakus D.(LDHA) rabbit NBP1-48336 Novus Biologicals 1:200 Lactate dehydrogenase B (LDHB) rabbit ab75167 Abcam 1:400 mouse ab90582 Abcam 1:100 rabbit bs-3995R Bioss 1:100 rabbit HPA021451 Atlas Antibodies 1:50 rabbit PRS4051 Sigma-Aldrich 1:400 mouse ab40084 Abcam 1:50 anti-rabbit

(16) The circadian clock regulates RPE-mediated lactate transport via SLC16A1 (MCT1)Experimental Eye ResearchJanuary 1, 2020Nemanja Milićević, Jacoline B. ten Brink, Anneloor L.M.A. ten Asbroek, Arthur A. Bergen, Marie-Paule Felder-Schmittbuhlfollowing primary antibodies: 156 GLUT1 (R&D Systems, 40 µg/ml, MAB14181) and MCT1 (Abcam, 1:15, AB90582). After WESTM 157 quantification, we normalized the protein expression profiles of GLUT1 and MCT1

(17) Enhanced glycolytic metabolism supports transmigration of brain-infiltrating macrophages in multiple sclerosisThe Journal of clinical investigationMay 21, 2019Kaushik DK, Bhattacharya A, Mirzaei R, Rawji KS, Ahn Y, Rho JM, Yong VW.anti-F4/80 (MCA497EL; BD Biosciences); rabbit anti-GFAP (G3893, MilliporeSigma 1:400); or mouse anti–MCT-1 (ab90582, Abcam, 1:100) antibodies overnight at 4°C. After additional washes, sections were incubated with Alexa

(18) Lactate dehydrogenase is correlated with clinical stage and grade and is downregulated by si‑STAB1 in ovarian cancerOncology ReportsAugust 17, 2018Jiangdong Xiang, Lina Zhou, Yan Zhuang, Jin Zhang, Ya Sun, Shuangdi Li, Zhenbo Zhang, Gao Zhang, Yinyan Herabbit anti‑human SATB1 antibody (1:100; cat. no. ab92307) and anti‑human MCT1 antibody (1:100; cat. no. ab90582; both from Abcam, Cambridge, UK). The membranes were then washed 3 times for 5 min in PBST and incubated

(19) Branched-chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotypeEMBO reportsDecember 1, 2017Silva LS, Poschet G, Nonnenmacher Y, Becker HM, Sapcariu S, Gaupel AC, Schlotter M, Wu Y, Kneisel N, Seiffert M, et al.Anti-BCAT1 antibody (rabbit polyclonal antibody, Insight Biotechnology Limited) and anti-MCT1 antibody (ab90582, Abcam) were used at 1:100 dilution. Anti-MCT4 antibody (376140, Santa Cruz) and anti-PGK1 antibody

(20) Design, development and characterization of synthetic Bruch’s membranesActa BiomaterialiaDecember 1, 2017Denver C. Surrao, Ursula Greferath, Yu-Qian Chau, Stuart J. Skabo, Mario Huynh, Kinnari J. Shelat, Ioannis J. Limnios, Erica L. Fletcher, Qin LiuZO1 (1:100, Cat# 617-300, Invitrogen, USA), MITF (1:500, Cat# ab12039, Abcam, USA), MCT1 (1:50, Cat# ab90582, Abcam, USA) and MerTK (1:25, Cat# PA5-15028, Invitrogen, USA), reconstituted in cold 3% BSA. Samples

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Anti-Monocarboxylic acid transporter 1 antibody from Abcam

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Anti-Monocarboxylic acid transporter 1 antibody from Abcam

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