Anti-Lamin A antibody [133A2] ab8980 from Abcam

Product Specs
ItemAnti-Lamin A antibody [133A2]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab8980
Antibody TypePrimary
Quantity100 UG
ClonalityMonoclonal
HostMouse, Nude mouse
IsotypeIgG3
ApplicationsFlow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunohistochemistry (Frozen sections), Western blot
Clone133A2
Conjugate/TagUnconjugated
Concentration1 mg/ml
Research AreaEpigenetics
Gene NameLMNA
ValidationKnockOut Validated
ReactivityHuman, Mouse
TargetLamin A

Add to Compare List

Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Imaging and AI based chromatin biomarkers for diagnosis and therapy evaluation from liquid biopsiesNPJ Precis OncolDecember 14, 2023Kiran Challa, Daniel Paysan, Dominic Leiser, Nadia Sauder, Damien C. Weber, G. V. ShivashankarCell Signaling Technologies (catalog no. 2577 S), monoclonal mouse anti-Lamin A/C from Abcam (catalog no. ab8980), monoclonal rat anti-CD3 from Abcam (catalog no. ab11089), recombinant Alexa Fluor 647 anti-CD8 alpha

(2) AKT2-mediated nuclear deformation leads to genome instability during epithelial-mesenchymal transitioniScienceJune 16, 2023Jia-Rong Fan, Sung-Nian Chang, Ching-Tung Chu, Hong-Chen ChenRESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ,, Mouse monoclonal anti-lamin A,Abcam,Cat#ab8980 Rabbit polyclonal anti-lamin A pS392,Abcam,Cat#ab58528 Rabbit polyclonal anti-lamin B1,Abcam,Cat#ab155319 Rabbit

(3) Nucleophagy delays aging and preserves germline immortalityNat AgingJanuary 1, 2023Papandreou ME, Konstantinidis G, Tavernarakis N.washed with Dulbecco’s PBS and incubated with primary antibodies (1:50): mouse anti-lamin A (catalog no. ab8980; Abcam) and rabbit anti-fibrillarin or rabbit anti-nesprin-2 in 1% bovine serum albumin (BSA) (catalog

(4) Cystathionine β-synthase is required for oocyte quality by ensuring proper meiotic spindle assemblyCell proliferationDecember 1, 2022Cao Y, Zhu X, Zhen P, Tian Y, Ji D, Xue K, Yan W, Chai J, Liu H, Wang W.Santa Cruz Biotechnology (Cat#: sc‐137025); mouse monoclonal anti‐Lamin A antibody was purchased from Abcam (Cat#: ab8980); mouse monoclonal anti‐Alpha tubulin antibody was purchased from Proteintech (Cat#: 66031‐1‐Ig); rabbit

(5) ISGylation of EMD promotes its interaction with PDHA to inhibit aerobic oxidation in lung adenocarcinomaJournal of Cellular and Molecular MedicineOctober 1, 2022Congcong Zhang, Jiangtao Cui, Leiqun Cao, Xiaoting Tian, Yayou Miao, Yikun Wang, Shiyu Qiu, Wanxin Guo, Lifang Ma, Jinjing Xia, et al.For IB, anti‐EMD (Abcam, #ab40688 and #ab204987), anti‐Actin (Abcam, #ab6276), anti‐Lamin A (Abcam, #ab8980), anti‐Nesprin1 (Abcam, #ab192234), anti‐Nesprin3 (Abcam, #ab186746), anti‐SUN domain‐containing protein

(6) Isosteviol Sodium (STVNA) Reduces Pro-Inflammatory Cytokine IL-6 and GM-CSF in an In Vitro Murine Stroke Model of the Blood–Brain Barrier (BBB)PharmaceuticsAugust 23, 2022Moritz Reschke, Ellaine Salvador, Nicolas Schlegel, Malgorzata Burek, Srikanth Karnati, Christian Wunder, Carola Y. Försterglucocorticoid receptor (1:200, Santa Cruz, #sc-8992; 1:500, Santa Cruz, #sc-393232), lamin A (1:500, Abcam, #ab8980) and tubulin (1:10000, Abcam, #ab197740), followed by secondary antibodies anti-mouse/rabbit (1:3000,

(7) An epigenetic small molecule screen to target abnormal nuclear morphology in human cellsMolecular Biology of the CellMay 15, 2022Kalina R. Atanasova, Saptarshi Chakraborty, Ranjala Ratnayake, Kshitij D. Khare, Hendrik Luesch, Tanmay P. Leleagain with 100 µl/well DPBS and treated with 25 µl/well anti-Lamin A mouse monoclonal antibody (Abcam; #ab8980) at 1:1000 dilution in permeabilization buffer overnight at 4°C. The next day, plates were washed 2×

(8) Coordinated changes in gene expression, H1 variant distribution and genome 3D conformation in response to H1 depletionNucleic Acids ResearchApril 22, 2022Núria Serna-Pujol, Mónica Salinas-Pena, Francesca Mugianesi, François Le Dily, Marc A Marti-Renom, Albert Jordananti-H1.3 (Abcam, ab24174), anti-H1.5 (Abcam, ab24175), anti-H3 (Abcam, ab1791) and anti-Lamin A (Abcam, ab8980). In situ Hi-C Hi-C libraries were generated from T47D multiH1 shRNA cells treated or not with Dox,

(9) Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated CellsCellsFebruary 2, 2022Lampart A, Sluzalska KD, Czyrek A, Szerszen A, Otlewski J, Wiedlocha A, Zakrzewska M.(Danveres, MA, USA); goat anti-FGF1 (AF232) from R&D Systems (Minneapolis, MN, USA); mouse anti-lamin A (ab8980)and rabbit anti-FGFR3 (ab10559) from Abcam (Cambridge, UK); rabbit anti-pFGFR1 (06-1433) from Merck

(10) Negative correlation between the nuclear size and nuclear Lamina component Lamin A in intraductal papillary mucinous neoplasms of the pancreasPathology oncology research : PORJanuary 1, 2022Hiroe T, Moriya S, Kobayashi S, Nishijima Y, Watanabe A, Shirabe K, Ikota H, Yokoo H, Saio M.Antigen,Clone,Species,Concentration/dilution,"Catalog No., company, location" Lamin A,133A2,Mouse monoclonal,2 μg/ml,"ab8980, Abcam, Cambridge, United Kingdom" Emerin,CL0201,Mouse monoclonal,2 μg/ml,"NBP2-52876, Novus Biologicals,

(11) Role of Lamin A and emerin in maintaining nuclear morphology in different subtypes of ovarian epithelial cancerOncology lettersJanuary 1, 2022Watabe S, Kobayashi S, Hatori M, Nishijima Y, Inoue N, Ikota H, Iwase A, Yokoo H, Saio M.monoclonal; cat. no. ab233984; Abcam), anti-Lamin A (1:500; clone 133A2; mouse monoclonal; cat. no. ab8980; Abcam) and anti-emerin (1:500; clone CL0201; mouse monoclonal; cat. no. NBP2-52876; Novus Biologicals,

(12) Lamin C is required to establish genome organization after mitosisGenome BiologyDecember 1, 2021Xianrong Wong, Victoria E. Hoskins, Ashley J. Melendez-Perez, Jennifer C. Harr, Molly Gordon, Karen L. ReddyImmunoresearch) for secondary detection. Other antibodies used for immunofluorescence were Anti-lamin A antibody (ab8980, Mouse IgG3, Abcam) at a concentration of 1/200, Anti-lamin C antibody (ab125679, Rabbit IgG, Abcam)

(13) Tyrosine phosphorylation of lamin A by Src promotes disassembly of nuclear lamina in interphaseLife Science AllianceOctober 1, 2021Ching-Tung Chu, Yi-Hsuan Chen, Wen-Tai Chiu, Hong-Chen Chenthrough a custom antibody production service provided by GeneTex, Inc. The mouse monoclonal anti-lamin A (ab8980) that recognizes a.a. 598–611 of lamin A, rabbit polyclonal anti-lamin B1 (ab16375) and anti-lamin B2

(14) Increase in lamin B1 promotes telomere instability by disrupting the shelterin complex in human cellsNucleic Acids ResearchSeptember 27, 2021Gaëlle Pennarun et al.or Santa Cruz B5), rabbit anti-lamin B1 (ab16048, Abcam), mouse anti-RAP1 (ab14404, Abcam), lamin A (ab8980, Abcam) and lamin A/C (cs4777, Cell signaling). Rabbit anti-ß-actin (2066, Sigma) or mouse anti-Vinculin

(15) Carthamin yellow improves cerebral ischemia‑reperfusion injury by attenuating inflammation and ferroptosis in ratsInternational journal of molecular medicineApril 1, 2021Guo H, Zhu L, Tang P, Chen D, Li Y, Li J, Bao C.2021 3 Figure 1. Chemical structure of carthamin yellow. Group, Inc.) and Lamin A (1:1,000; cat. no. ab8980; Abcam). After washing with TBST (0.1% Tween‑20), the membranes were incubated with appropriate secondary

(16) Micropatterned Surfaces Expose the Coupling between Actin Cytoskeleton‐Lamin/Nesprin and Nuclear Deformability of Breast Cancer Cells with Different MalignanciesAdvanced BiologyJanuary 1, 2021Ezgi Antmen, Utkan Demirci, Vasif HasirciA/C and Nesprin-2, the antibodies specific to these proteins (Anti-Nesprin-2 ab57397 and anti-Lamin-A ab8980, Abcam, UK) were used according to manufacturer’s directions. TOPRO-3 (1:1000, in PBS) (Invitrogen,

(17) The Formation of Melanocyte Apoptotic Bodies in Vitiligo and the Relocation of Vitiligo Autoantigens under Oxidative StressOxidative medicine and cellular longevityJanuary 1, 2021Tian J, Wang Y, Ding M, Zhang Y, Chi J, Wang T, Jiao B, Jian Z, Yi X, Huang Y, et al.Billerica, MA). Samples were then incubated with the following antibodies: anti-Lamin A (1 : 5000, ab8980, Abcam), anti-Lamin A/C (Asp230) (1 : 10000, ab108595, Abcam), anti-tyrosinase (1 : 5000, ab170905,

(18) Ling-Gui-Zhu-Gan Decoction Protects H9c2 Cells against H2O2-Induced Oxidative Injury via Regulation of the Nrf2/Keap1/HO-1 Signaling PathwayEvidence-Based Complementary and Alternative MedicineNovember 30, 2020Xiang Wang, Tongjuan Tang, Mengting Zhai, Ruirui Ge, Liang Wang, Jinling Huang, Peng Zhou,1 : 1000 Keap1,Abcam,ab139729,1 : 1000 HO-1,Abcam,ab6046,1 : 2000 Nrf2,Abcam,ab137550,1 : 1000 Lamin A,Abcam,ab8980,1 : 2000 GAPDH,Abcam,ab181602,1 : 1000 Goat anti-rabbit IgG H&L(HRP),Abcam,ab6721,1 : 10000 Rabbit anti-mouse IgG H&L(HRP

(19) Lack of sphingomyelin synthase 2 reduces cerebral ischemia/reperfusion injury by inhibiting microglial inflammation in miceExperimental and Therapeutic MedicineOctober 22, 2020Yu Yang, Fengxian Hu, Guifeng Yang, Qingmei Mengab76245; Abcam; 1:1,000), anti-NF-κB-p65 (cat. no. ab16502; Abcam; 1:1,000), anti-lamin A (cat. no. ab8980; Abcam; 1:1,000), or anti-β-actin antibody (cat. no. ab8227; Abcam; 1:2,000) diluted in 5% skim milk

(20) Lamin A-mediated nuclear lamina integrity is required for proper ciliogenesisEMBO reportsOctober 5, 2020Fan JR, You LR, Wang WJ, Huang WS, Chu CT, Chi YH, Chen HC.efforts. Materials and Methods Antibodies and reagents The anti‐progerin (ab66587), anti‐lamin A (ab8980), anti‐aquaporin 1 (ab65837), anti‐Arl3b (ab136648), and anti‐pericentrin (ab4448) antibodies were purchased

Be the First to Write a Review!

Anti-Lamin A antibody [133A2] from Abcam

Abcam

Citations (78)

Reviews

Anti-Lamin A antibody [133A2] from Abcam

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map