Anti-P Glycoprotein antibody [JSB-1] ab3366 from Abcam

Product Specs
ItemAnti-P Glycoprotein antibody [JSB-1]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab3366
Antibody TypePrimary
HostMouse, Nude mouse
IsotypeIgG1
CloneJSB-1
ClonalityMonoclonal
Quantity250 UL
ApplicationsImmunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Conjugate/TagUnconjugated
Gene NameABCB1
ReactivityHuman
TargetP Glycoprotein

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Core Fucosylation Mediated by the FucT-8 Enzyme Affects TRAIL-Induced Apoptosis and Sensitivity to Chemotherapy in Human SW480 and SW620 Colorectal Cancer CellsInternational journal of molecular sciencesJuly 25, 2023López-Cortés R, Correa Pardo I, Muinelo-Romay L, Fernández-Briera A, Gil-Martín E.dilution, 66118-1-Ig) from Proteintech (Chicago, IL, USA) or 100 µL of anti-PGP antibody (1/25 dilution, ab3366) from Abcam (Cambridge, UK) in PBS with 1.0% BSA. Secondary incubation consisted of 100 µL of the green

(2) The relationship among amyloid-β deposition, sphingomyelin level, and the expression and function of P-glycoprotein in Alzheimer's disease pathological processNeural regeneration researchJune 1, 2023Xing ZK, Du LS, Fang X, Liang H, Zhang SN, Shi L, Kuang CX, Han TX, Yang Q.Cat# bs-0107R, RRID: AB_10858046), mouse monoclonal anti-P-glycoprotein antibody (1:50, Abcam, Cat# ab3366, RRID: AB_303744), Alexa Fluor 488-Labeled goat anti-rabbit fluorescent antibody (1:1000, Abcam, Cat#

(3) ABCB1 Amplicon Contains Cyclic AMP Response Element-Driven TRIP6 Gene in Taxane-Resistant MCF-7 Breast Cancer SublinesGenes (Basel)January 23, 2023Petr Daniel, Kamila Balušíková, Radka Václavíková, Karolína Šeborová, Šárka Ransdorfová, Marie Valeriánová, Longfei Wei, Michael Jelínek, Tereza Tlapáková, Thomas Fleischer, et al.performed as described elsewhere [44]. The primary antibodies that were used were anti-P-glycoprotein (ab3366, RRID: AB_303744), anti-actin (ab11003, RRID: AB_297660) from Abcam (Cambridge, UK), and anti-TRIP6

(4) Ultrasound Triggers Hypericin Activation Leading to Multifaceted Anticancer ActivityPharmaceuticsMay 21, 2022Federica Foglietta, Roberto Canaparo, Simone Cossari, Patrizia Panzanelli, Franco Dosio, Loredana SerpeFinally, P-gp expression was evaluated via flow cytometry using a mouse anti-P-gp primary antibody (Ab3366, Abcam, Cambridge, UK) at a dilution of 1:200 in 2.0 × 105 cells for 30 min at room temperature. At

(5) Hsa_circ_0007142 contributes to cisplatin resistance in esophageal squamous cell carcinoma via miR‐494‐3p/LASP1 axisJournal of Clinical Laboratory AnalysisMay 1, 2022Na Chang, Ning Ge, Yufei Zhao, Liu Yang, Wei Qin, Yayun Cuimilk for 2 h. Next, the membranes were incubated with primary antibodies against P‐glycoprotein (P‐gp; ab3366; Abcam), glutathione S‐transferase π (GST‐π; ab53942; Abcam), LASP1 (ab156872; Abcam), or GAPDH (ab8245;

(6) Interaction of Hepatitis B Virus X Protein with the Pregnane X Receptor Enhances the Synergistic Effects of Aflatoxin B1 and Hepatitis B Virus on Promoting HepatocarcinogenesisJournal of Clinical and Translational HepatologyAugust 28, 2021Yongdong Niu, Shaohua Fan, Qin Luo, Liming Chen, Danmei Huang, Wenjun Chang, Wenxin Qin, Ganggang Shi(MAB8419; Millipore, Danver, MA, USA), PXR (PP-H4417-00; R&D Systems, Minneapolis, MN, USA), MDR1 (ab3366; Abcam, Cambridge, UK), CYP3A4 (H00001576-B01P; Novus Biologicals, Littleton, CO, USA), SULT2A1 (ab38416;

(7) Bioengineered Multicellular Liver Microtissues for Modeling Advanced Hepatic Fibrosis Driven Through Non-Alcoholic Fatty Liver DiseaseSmall (Weinheim an der Bergstrasse, Germany)April 1, 2021Cho HJ, Kim HJ, Lee K, Lasli S, Ung A, Hoffman T, Nasiri R, Bandaru P, Ahadian S, Dokmeci MR, et al.Novus Biologicals), αSMA Ab (mouse, NBP2-33006, Novus Biologicals), anti-P-glycoprotein Ab (mouse, ab3366, Abcam), anti-CYP3A4 Ab (rabbit, ab135813, Abcam), anti-MRP2 Ab (mouse, ab3373, Abcam), or anti-SLCO1B1

(8) Editing Myosin VB Gene to Create Porcine Model of Microvillus Inclusion Disease, With Microvillus-Lined Inclusions and Alterations in Sodium TransportersGastroenterologyJune 1, 2020Engevik AC, Coutts AW, Kaji I, Rodriguez P, Ongaratto F, Saqui-Salces M, Medida RL, Meyer AR, Kolobova E, Engevik MA, et al.Actin Santa Cruz Biotech SC-65638 AF647 1:100 GM130 BD Biosciences 610822 1:200 MDR1 Abcam Ab3366 1:200 MRP2 Enzo ALX-801-016-C250 1:200 MYO5B Novus Biologicals NBP1-87746 1:200 NHE3 Novus Biologicals

(9) P-glycoprotein Expression Is Upregulated in a Pre-Clinical Model of Traumatic Brain InjuryNeurotrauma RepJanuary 1, 2020Vita SM, Redell JB, Maynard ME, Zhao J, Grill RJ, Dash PK, Grayson BE.100%). Antibodies The following antibodies were used in these studies: anti-Pgp antibodies (#ab170904, #ab3366, AbCam, Cambridge, MA; and MA1-26528, Thermo Scientiﬁc), astrocytic marker glial ﬁbrillary acidic protein

(10) Developmental differences in the expression of ABC transporters at rat brain barrier interfaces following chronic exposure to diallyl sulfideScientific ReportsDecember 1, 2019Liam M. Koehn, Katarzyna M. Dziegielewska, Kjeld Møllgård, Elodie Saudrais, Nathalie Strazielle, Jean-Francois Ghersi-Egea, Norman R. Saunders, Mark D. HabgoodAntibody,Host IgG,Dilution,Retrieval,Supplier,Code Number PGP (abcb1),Mouse IgG1,1:15–1:30,TEG,Abcam,ab3366 BCRP (abcg2),Mouse IgG2a,1:15–1:20,M6,Abcam,ab3380 MRP1 (abcc1),Mouse IgG2a,1:30–1:50,M6,Abcam,ab24102 MRP2

(11) Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) PathwayMedical science monitor : international medical journal of experimental and clinical researchJanuary 3, 2019Chen L, Yang G, Dong H.overnight. The primary antibodies against ALDH1 (ab129815), Nanog (ab80892), ABCG2 (ab203397), MDR1 (ab3366), p-mTOR (ab84400), cleaved caspase-3 (ab32042), and cleaved PARP (ab32064) were purchased from Abcam.

(12) Acute pain alters P-glycoprotein-containing protein complexes in rat cerebral microvessels: Implications for P-glycoprotein traffickingJournal of Cerebral Blood Flow & MetabolismDecember 1, 2018Margaret E Tome, Chelsea K Jarvis, Charles P Schaefer, Leigh M Jacobs, Joseph M Herndon, Kristen C Hunn, Nathan B Arkwright, Kathryn L Kellohen, Peyton C Mierau, Thomas P Davisfrom Sigma-Aldrich, (ab2910) from AbCam and (BD606100) from BD Biosciences (San Jose, CA); PgP (orb11267) from Biorbyt and (ab3366) from AbCam and AlexaFluor488 goat anti-rabbit (A-11008) and AlexaFLuor568 goat anti-mouse (A-11004)

(13) Brain barriers and functional interfaces with sequential appearance of ABC efflux transporters during human developmentScientific ReportsDecember 1, 2017Kjeld Møllgård, Katarzyna M. Dziegielewska, Camilla B. Holst, Mark D. Habgood, Norman R. Saundersantibodies,Host IgG,Dilution,Retrieval,Producer,Code number ABCB1/PGP,Mouse IgG1,1:15–1:30,TEG,Abcam,ab3366 ABCC1/MRP1,Mouse IgG2a,1:30–1:50,M6,Abcam,ab24102 ABCG2/BCRP,Mouse IgG2a,1:15–1:20,M6,Abcam,ab3380 AFP,Rabbit

(14) Short-term spheroid culture of primary colorectal cancer cells as an in vitro model for personalizing cancer medicinePLOS ONESeptember 6, 2017Maria Jeppesen, Grith Hagel, Anders Glenthoj, Ben Vainer, Per Ibsen, Henrik Harling, Ole Thastrup, Lars N. Jørgensen, Jacob Thastrup

(15) Extracts of Immature Orange (Aurantii fructus immaturus) and Citrus Unshiu Peel (Citri unshiu pericarpium) Induce P-Glycoprotein and Cytochrome P450 3A4 Expression via Upregulation of Pregnane X ReceptorFrontiers in PharmacologyFebruary 21, 2017Naoto Okada, Aki Murakami, Shiori Urushizaki, Misa Matsuda, Kazuyoshi Kawazoe, Keisuke IshizawaJapan), and Biowest (Nuaillé, France), respectively. Mouse anti-CYP3A4 (ab3572) and rabbit anti-P-gp (ab3366) antibodies were purchased from Abcam (Cambridge, UK). Rabbit anti-β-actin antibody (#4967) was purchased

(16) Geniposide reverses multidrug resistance in vitro and in vivo by inhibiting the efflux function and expression of P-glycoproteinExperimental and Therapeutic MedicineFebruary 1, 2017Hefei Huang, Xuenong Zhang, Zhixiong Huang, Ye Zhang, Zhiyong Zhoupurchased from Sigma-Aldrich, Merck Millipore (Darmstadt, Germany). Monoclonal antibodies against ABCB1 (ab3366) were purchased from Abcam, Ltd., (Hong Kong, China). Cell lines and cell culture The MG63 human osteosarcoma

(17) DNMT3A R882 mutations promote anthracycline resistance in acute myeloid leukemia through impaired nucleosome remodelingNature MedicineDecember 1, 2016Olga A. Guryanova et al.Cruz Biotechnology; and histone H2A (ab18255), histone H3 (ab1791), H3K36me3 (ab9050), P-glycoprotein (ab3366), MRP1 (ab3369), and RPA32 (ab16850) from Abcam. Co-immunoprecipitation experiment with DNMT3A-specific

(18) Resveratrol reverses P-glycoprotein-mediated multidrug resistance of U2OS/ADR cells by suppressing the activation of the NF-κB and p38 MAPK signaling pathwaysOncology LettersNovember 1, 2016Rui Zhang, Ming Lu, Zhen Zhang, Xiliang Tian, Shouyu Wang, Decheng LvThermo Fisher Scientific, Inc. (Waltham, MA, USA). Antibodies against β‑actin (catalog no. ab8226) and MDR1 (catalog no. ab3366) were purchased from Abcam (Cambridge, MA, USA). High glucose Dulbecco's modified Eagle (DMEM) medium

(19) P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory painJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismNovember 1, 2016Tome ME, Herndon JM, Schaefer CP, Jacobs LM, Zhang Y, Jarvis CK, Davis TP.antibodies were used for staining: MDR1 (orb11267; 1:5 dilution) from Biorbyt (San Francisco, CA); MDR1 (ab3366; 1:5 dilution), GLUT1 (ab32551; 1:10 dilution), GLUT1 (ab40084; 1:10 dilution), PTRF/cavin1 (ab48824;

(20) Does the Clearance of Inhaled^99mTc-Sestamibi Correlate with Multidrug Resistance Protein 1 Expression in the Human Lung?RadiologySeptember 1, 2016Hosahalli K. Mohan, Thomas Routledge, Paul Cane, Lefteris Livieratos, James R. Ballinger, Adrien M. PetersTuscon, Ariz). Immunostaining procedure was standardized by using control tissue. JSB-1 mouse antibody (ab3366; AbCam, Cambridge, United Kingdom) was used for P-gp detection (1:50 dilution) and anti-MRP-1 mouse

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Anti-P Glycoprotein antibody [JSB-1] from Abcam

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Anti-P Glycoprotein antibody [JSB-1] from Abcam

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