Anti-pan Cytokeratin antibody [C-11] ab7753 from Abcam

Product Specs
ItemAnti-pan Cytokeratin antibody [C-11]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab7753
Antibody TypePrimary
Quantity100 UG
CloneC-11
ApplicationsFlow Cytometry, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Multiplex immunohistochemistry, Western blot
IsotypeIgG1
ClonalityMonoclonal
HostMouse, Nude mouse
Conjugate/TagUnconjugated
FormatPurified from ascites using precipitation methods
Concentration1 mg/ml
Gene NameKRT18
ReactivityHuman, Mouse, Rat
Targetpan Cytokeratin

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Website: http://www.abcam.com

(1) Multiplexed and Millimeter-Scale Fluorescence Nanoscopy of Cells and Tissue Sections via Prism-Illumination and Microfluidics-Enhanced DNA-PAINTChemical & Biomedical ImagingDecember 25, 2023Matthew J. Rames, John P. Kenison, Daniel Heineck, Fehmi Civitci, Malwina Szczepaniak, Ting Zheng, Julia Shangguan, Yujia Zhang, Kai Tao, Sadik Esener, et al.(Abcam, ab2910), Chicken-antivimentin antibody (Sigma-Aldrich, AB5733), and Mouse panCytokeratin (Abcam, ab7753). For all remaining experimental steps and sample processing and labeling (fixation, permeabilization,

(2) Cancer CD39 drives metabolic adaption and mal-differentiation of CD4+ T cells in patients with non-small-cell lung cancerCell Death DisDecember 8, 2023Ying Wang, Mengdi Liu, Lei Zhang, Xiyu Liu, Huiyan Ji, Yan Wang, Jun Gui, Yan Yue, Zhenke Wenwas changed twice every week. The PDOs culture medium and verification using anti-human PanCK (Abcam, ab7753), anti-human CD31 (Abcam, 281583), and histological analyses, were performed as previously described

(3) LncRNA MIR200CHG inhibits EMT in gastric cancer by stabilizing miR-200c from target-directed miRNA degradationNat CommunDecember 8, 2023Yixiao Zhu, Chengmei Huang, Chao Zhang, Yi Zhou, Enen Zhao, Yaxin Zhang, Xingyan Pan, Huilin Huang, Wenting Liao, Xin Wanguse the clinical specimens for research purposes. Immunohistochemistry (IHC) IHC for panCK (ABcam, ab7753), E-cadherin (Proteintech, 20874-1-AP), and vimentin (Proteintech, 10366-1-AP) was performed as previously

(4) Components of the tumor immune microenvironment based on m-IHC correlate with prognosis and subtype of triple-negative breast cancerCancer MedDecember 7, 2023Luyi Lin, Haiming Li, Xin Wang, Zezhou Wang, Guanhua Su, Jiayin Zhou, Shiyun Sun, Xiaowen Ma, Yan Chen, Chao You, et al.antibodies to PD‐L1 (ab237727, Abcam, 1:250), mouse monoclonal [C‐11] antibodies to pancytokeratin (ab7753, Abcam, 1:150), rabbit monoclonal [SP7] antibodies to CD3 (ab16669, Abcam, 1:150), rabbit monoclonal

(5) Heterogeneity in tertiary lymphoid structures predicts distinct prognosis and immune microenvironment characterizations of clear cell renal cell carcinomaJ Immunother CancerDecember 1, 2023Wenhao Xu, Jiahe Lu, Wang-Rui Liu, Aihetaimujiang Anwaier, Yuhao Wu, Xi Tian, Jia-Qi Su, Yuan-Yuan Qu, Jianfeng Yang, Hailiang Zhang, et al.(Abcam, ab75813, 1:100), CD20 (Dako, L26, IR604), FoxP3 (Abcam, ab20034, 1:100) and pan-CK (Abcam, ab7753, 1:100) were procured from Akoya Biosciences. Formalin-fixed paraffin-embedded (FFPE) tissue slides

(6) CCL19: a novel prognostic chemokine modulates the tumor immune microenvironment and outcomes of cancersAging (Albany NY)November 15, 2023Qiang Gu, Shifang Zhou, Cong Chen, Zhi Wang, Wenhao Xu, Jiarong Zhang, Shiyin Wei, Jianfeng Yang, Hongjing Chen(Abcam, ab75813, 1:100), CD20 (Dako, L26, IR604), FoxP3 (Abcam, ab20034, 1:100) and pan-CK (Abcam, ab7753, 1:100) were obtained from Akoya Biosciences (Marlborough, MA, USA). Tissue slides that were bound with

(7) Comparative study of the efficacy of intra-arterial and intravenous transplantation of human induced pluripotent stem cells-derived neural progenitor cells in experimental strokePeerJNovember 9, 2023Elvira Cherkashova, Daria Namestnikova, Georgiy Leonov, Ilya Gubskiy, Kirill Sukhinich, Pavel Melnikov, Vladimir Chekhonin, Konstantin Yarygin, Dmitry Goldshtein, Diana Salikhovafor markers of three germ layers using primary antibodies against pan-cytokeratin (ectoderm marker, ab7753, Abcam, Boston, MA, USA), vimentin (mesoderm marker, ab92547, Abcam, Boston, MA, USA), α-fetoprotein

(8) Multi-omics indicators of long-term survival benefits after immune checkpoint inhibitor therapyCell Reports MethodsOctober 23, 2023Jie Zhao, Yiting Dong, Hua Bai, Fan Bai, Xiaoyan Yan, Jianchun Duan, Rui Wan, Jiachen Xu, Kailun Fei, Jie Wang, et al.IR604" anti-CD56,Abcam,Cat#ab75813 anti-CD4,Abcam,Cat#ab133616 anti-FoxP3,Abcam,Cat#ab20034 anti-CD3,Daco,Cat#A0452 anti-panCK,Abcam,Cat#ab7753 ,, Biological samples,Biological samples,Biological samples ,, Lung cancer samples (n = 30),This

(9) Integration of single-cell RNA sequencing and bulk RNA transcriptome sequencing reveals a heterogeneous immune landscape and pivotal cell subpopulations associated with colorectal cancer prognosisFrontiers in ImmunologyAugust 22, 2023Qian Zhang, Yang Liu, Xinyu Wang, Cheng Zhang, Mingxiao Hou, Yunen Liu(Abcam, ab182422), CD44 (Abcam, ab6124), SPP1 (Osteopontin) (Abcam, ab214050), pan Cytokeratin (Abcam, ab7753), Foxp3 (Abcam, ab215206). Statistical analysis Statistical analysis was performed with R 4.2.3, SPSS

(10) Histone deacetylase-mediated tumor microenvironment characteristics and synergistic immunotherapy in gastric cancerTheranosticsAugust 18, 2023Yilin Lin, Xiangxiang Jing, Zhihua Chen, Xiaoxian Pan, Duo Xu, Xiang Yu, Fengyun Zhong, Long Zhao, Changjiang Yang, Bo Wang, et al.with anti-fluorescence quenching tablets. Antibodies against CD8α (ab237709), CD4 (ab183685), pan-CK (ab7753) and PD-L1 (ab213480) were purchased from Abcam. The slices were placed under a scanner to capture images.

(11) Neoadjuvant sintilimab in combination with concurrent chemoradiotherapy for locally advanced gastric or gastroesophageal junction adenocarcinoma: a single-arm phase 2 trialNat CommunAugust 14, 2023Jia Wei, Xiaofeng Lu, Qin Liu, Yao Fu, Song Liu, Yang Zhao, Jiawei Zhou, Hui Chen, Meng Wang, Lin Li, et al.stained with DAPI. Tumor parenchyma and stroma were differentiated according to pan-CK staining (Abcam, ab7753, 1:100). Digital image analysis was performed with the APTIME image analysis software (3D Medicines).

(12) Neoadjuvant adebrelimab in locally advanced resectable esophageal squamous cell carcinoma: a phase 1b trialNature medicineAugust 1, 2023Yin J, Yuan J, Li Y, Fang Y, Wang R, Jiao H, Tang H, Zhang S, Lin S, Su F, et al.dilution 1:200; Abcam, catalog no. Ab16669), Pan-CK (clone C-11, dilution 1:800; Abcam, catalog no. Ab7753), Vimentin (clone EPR3776, dilution 1:600; Abcam, catalog no. Ab92547), Ki-67 (clone SP6, dilution 1:100;

(13) Distinct immune microenvironment of lung adenocarcinoma in never-smokers from smokersCell reports. MedicineJune 20, 2023Luo W, Zeng Z, Jin Y, Yang L, Fan T, Wang Z, Pan Y, Yang Y, Yao M, Li Y, et al.(BioLegend, Cat# 916104), FOXP3 (Thermo Fisher Scientific, Cat# 14-4776-80) and PanCK (Abcam, Cat# ab7753), CD47 (Abcam, Cat# ab226837), PD-L1 (Abcam, Cat# ab213524), CD4 (Abcam, Cat# ab133616) and MHC-II (Abcam,

(14) Exploration of the immunogenetic landscape of hyperprogressive disease after combined immunotherapy in cancer patientsiScienceJune 16, 2023Caifeng Gong, Wen Zhang, Yongkun Sun, Jianzhong Shou, Zhichao Jiang, Tianyi Liu, Shengzhou Wang, Jun Liu, Ying Sun, Aiping ZhouTechnology Cat#86183S), anti-PD-L1 (Cell Signaling Technology Cat#13684S), and anti-panCK (Abcam Cat#ab7753). The labeled slides were scanned using a Vectra Polaris Automated Quantitative Pathology Imaging System

(15) MEX3B inhibits collagen production in eosinophilic nasal polyps by downregulating epithelial cell TGFBR3 mRNA stabilityJCI InsightMay 8, 2023Jin-Xin Liu, Ao-Nan Chen, Qihong Yu, Ke-Tai Shi, Yi-Bo Liu, Cui-Lian Guo, Zhe-Zheng Wang, Yin Yao, Li Pan, Xiang Lu, et al.epithelial cells based on cytokeratin immunofluorescence staining with an anti–pan-cytokeratin Ab (catalog ab7753, mouse, Abcam) (50). Because of the limited quantity of tissue and cell samples, not all samples were

(16) Genomic and transcriptomic features between primary and paired metastatic fumarate hydratase–deficient renal cell carcinomaGenome MedicineMay 2, 2023Jiayu Liang, Guangxi Sun, Xiuyi Pan, Mengni Zhang, Pengfei Shen, Sha Zhu, Jinge Zhao, Linmao Zheng, Junjie Zhao, Yuntian Chen, et al.UK)); PD-1: D4W2J(86163S, CST, Massachusetts, USA); PD-L1: E1L3N(13684S, CST, Massachusetts, USA): CK: ab7753(Abcam, Cambridge, UK); S100: ab52642 (Abcam, Cambridge, UK). PD-L1 expression was assessed by tumor

(17) Tumor Immunophenotyping‐Derived Signature Identifies Prognosis and Neoadjuvant Immunotherapeutic Responsiveness in Gastric CancerAdvanced ScienceMay 1, 2023Jia‐Bin Wang, Qing‐Zhu Qiu, Qiao‐Ling Zheng, Ya‐Jun Zhao, Yu Xu, Tao Zhang, Shuan‐Hu Wang, Quan Wang, Qin‐Wen Jin, Yin‐Hua Ye, et al.an Opal 4‐color Kit (NEL840001KT, Akoya Bioscience, USA). Labeling of multi‐cytokeratin using panCK (ab7753, Abcam, UK) in all panels was used to segment the tumor nest and stroma or determine the IM. The nuclei

(18) Prognostic values of tissue-resident CD8+T cells in human hepatocellular carcinoma and intrahepatic cholangiocarcinomaWorld Journal of Surgical OncologyApril 6, 2023Lujun Chen, Hao Huang, Ziyi Huang, Junjun Chen, Yingting Liu, Yue Wu, An Li, Junwei Ge, Zhang Fang, Bin Xu, et al.antihuman CD8 (Catalog No.: M7103, clone: C8/144B, Dako, Denmark), and the anti-pan CK (Catalog No.: ab7753, clone: C11, Abcam, USA), were used in the present immunostaining. In the step of secondary antibody

(19) Chromosome 11q13 amplification correlates with poor response and prognosis to PD-1 blockade in unresectable hepatocellular carcinomaFrontiers in ImmunologyMarch 28, 2023Kai Yan, Ding Zhang, Yanan Chen, Wenfeng Lu, Mengli Huang, Jinping Cai, Shiqing Chen, Ting Bei, Yuezong Bai, Jian Lv, et al.(Dako, L26, IR604), CD56 (Abcam, ab75813, 1:100), FOXP3 (Abcam, ab20034, 1:100) and pan-CK (Abcam, ab7753, 1:100) (Akoya Biosciences). Next, secondary antibodies and reactive Opal fluorophores were incubated.

(20) Spatial distribution of CD3- and CD8-positive lymphocytes as pretest for POLE wild-type in molecular subgroups of endometrial carcinomaFrontiers in MedicineMarch 23, 2023Samuel H. Jungen, Luca Noti, Lucine Christe, Jose A. Galvan, Inti Zlobec, Michael D. Müller, Sara Imboden, Franziska Siegenthaler, Joseph W. Carlson, Teijo Pellinen, et al.Alexa-750,Red, CD8,"Dako, M7103*",mouse,HRP,1:300,Alexa-647,Green, PanCK,"panEpi-cocktail* Abcam, ab7753 Invitrogen, MA5-13156 BD, 610182",mouse,HRP,1:150 1:100 1:200,Alexa-750,Violet, Staining material

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Anti-pan Cytokeratin antibody [C-11] from Abcam

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Anti-pan Cytokeratin antibody [C-11] from Abcam

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