Anti-Aly/Ref antibody [11G5] ab6141 from Abcam

Product Specs
ItemAnti-Aly/Ref antibody [11G5]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab6141
Antibody TypePrimary
ClonalityMonoclonal
ApplicationsFlow Cytometry, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
IsotypeIgG1
Clone11G5
Quantity100 UL
HostMouse, Nude mouse
Conjugate/TagUnconjugated
FormatPurified from supernatant
Concentration1 mg/ml
Research AreaEpigenetics
Gene NameALYREF
ReactivityHuman
TargetAly

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Identification and verification of an ALYREF-involved 5-methylcytosine based signature for stratification of prostate cancer patients and prediction of clinical outcome and response to therapiesDiscover OncologyMay 8, 2023Xiao Tan, Zhouda Cai, Guo Chen, Chao Cai, Jiahong Chen, Yingke Liang, Yangjia Zhuo, Jianming Liu, Liangliang Huang, Bin Ouyang, et al.(Millipore, FFP39), followed by blocking with 5% skimmed milk and incubated with anti-ALYREF (Abcam, ab6141) and anti-β-actin (Santa Cruz, sc-47778) antibodies at 4 °C overnight. After incubated with secondary

(2) Identification of hnRNP-A1 as a pharmacodynamic biomarker of type I PRMT inhibition in blood and tumor tissuesScientific reportsDecember 17, 2020Noto PB, Sikorski TW, Zappacosta F, Wagner CD, Montes de Oca R, Szapacs ME, Annan RS, Liu Y, McHugh CF, Mohammad HP, et al.biotinylated anti-ADMA antibody, at a concentration of 0.5 µg/mL, and antibodies specific to ALYREF (Abcam, #ab6141), DHX9 (Abcam, #ab54593), EIF4H (Abcam, #ab77455), EWSR1 (Abcam, #ab54708), G3BP1 (Abcam, #ab56574),

(3) Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALSActa neuropathologicaAugust 1, 2020LaClair KD, Zhou Q, Michaelsen M, Wefers B, Brill MS, Janjic A, Rathkolb B, Farny D, Cygan M, de Angelis MH, et al.paraffin-embedded tissue sections as described previously [37] using the following antibodies: Alyref (ab6141, Abcam 1:50), ChAT (AB144P, Millipore 1:200), GFP (632381, Takara 1:250), Fus (A300-292A, Bethyl Labs

(4) The m⁶A-methylase complex recruits TREX and regulates mRNA exportScientific reportsSeptember 14, 2018Lesbirel S, Viphakone N, Parker M, Parker J, Heath C, Sudbery I, Wilson SA.A5060, YTHDC1 – Proteintech 14392-1-AP, SSRP1 – Biolegend 609701, TUBULIN – Sigma T5168, ALYREF – Abcam Ab6141, NXF1 – Abcam Ab50609, DDX39A/B and THOC5 were described previously3. RNA/Protein extraction from 293

(5) Accumulation of poly(A) RNA in nuclear granules enriched in Sam68 in motor neurons from the SMNΔ7 mouse model of SMAScientific reportsJune 25, 2018Narcís JO, Tapia O, Tarabal O, Piedrafita L, Calderó J, Berciano MT, Lafarga M.antibodies anti-SMN (610646, BD Transduction Laboratories, USA), anti-TMG-cap (NA02A, Oncogene), anti-REF (ab6141, Abcam), anti-Y14 (ab5828, Abcam) and anti-hnRNPM3/M4 (ab9548, Abcam), the rabbit polyclonal antibodies

(6) Cellular bases of the RNA metabolism dysfunction in motor neurons of a murine model of spinal muscular atrophy: Role of Cajal bodies and the nucleolusNeurobiology of DiseaseDecember 1, 2017Olga Tapia, Josep Oriol Narcís, Javier Riancho, Olga Tarabal, Lídia Piedrafita, Jordi Calderó, Maria T. Berciano, Miguel Lafargaused for immunofluorescence: the mouse monoclonal antibodies anti-TMG-cap (NA02A, Oncogene), anti-REF (ab6141, Abcam), anti-Y14 (ab5828, Abcam) and anti-hnRNPM3/M4 (ab9548, Abcam), the rabbit polyclonal antibodies

(7) ALS Associated Mutations in Matrin 3 Alter Protein-Protein Interactions and Impede mRNA Nuclear ExportScientific reportsNovember 6, 2017Boehringer A, Garcia-Mansfield K, Singh G, Bakkar N, Pirrotte P, Bowser R.

(8) WNK1 kinase and the termination factor PCF11 connect nuclear mRNA export with transcriptionGenes & developmentNovember 1, 2017Volanakis A, Kamieniarz-Gdula K, Schlackow M, Proudfoot NJ.(Santa Cruz Biotechnology, SC-816), WNK1 (Bethyl Laboratories, A301-514A), NPC (Abcam, ab24609), ALY (Abcam, ab6141), HA (Abcam, ab9110), PCF11 (Abcam, ab134391), pS326 OSR1 (Merck, 07-2273), and rabbit IgG control (Abcam,

(9) The metabolic sensors FXRα, PGC-1α, and SIRT1 cooperatively regulate hepatitis B virus transcriptionFASEB journal : official publication of the Federation of American Societies for Experimental BiologyMarch 1, 2014Curtil C, Enache LS, Radreau P, Dron AG, Scholtès C, Deloire A, Roche D, Lotteau V, André P, Ramière C.

(10) Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor INucleic acids researchAugust 1, 2013Katahira J, Okuzaki D, Inoue H, Yoneda Y, Maehara K, Ohkawa Y.

(11) GDNF Signaling Regulates YBX1/mRNA Interactions in Mouse SpermatogoniaBiology of ReproductionAugust 1, 2012Bart Phillips, Karen Peters, Kyle OrwigDavid Elliott, University of Newcastle upon Tyne, Newcastle upon Tyne, U.K.), Refbp1, 1:800 (Abcam, ab6141), Sfrs6, 1:500 (Abcam, ab28428), Sfrs10, 1:200 (Abcam, ab50513), Ybx1, 1:1600 (Abcam, ab12148). For

(12) The role of deimination in ATP5b mRNA transport in a transgenic mouse model of multiple sclerosisEMBO reportsMarch 1, 2012Ding D, Enriquez-Algeciras M, Dave KR, Perez-Pinzon M, Bhattacharya SK.

(13) Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancersBMC cancerFebruary 17, 2011Domínguez-Sánchez MS, Sáez C, Japón MA, Aguilera A, Luna R.

(14) The cellular DExD/H-box RNA-helicases UAP56 and URH49 exhibit a CRM1-independent nucleocytoplasmic shuttling activityPloS oneJanuary 1, 2011Thomas M, Lischka P, Müller R, Stamminger T.

(15) Individual influenza A virus mRNAs show differential dependence on cellular NXF1/TAP for their nuclear exportThe Journal of general virologyMay 1, 2010Read EK, Digard P.

(16) Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNAThe EMBO journalMarch 4, 2009Katahira J, Inoue H, Hurt E, Yoneda Y.

(17) The interaction between cap-binding complex and RNA export factor is required for intronless mRNA exportThe Journal of biological chemistryMay 25, 2007Nojima T, Hirose T, Kimura H, Hagiwara M.

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Anti-Aly/Ref antibody [11G5] from Abcam

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Anti-Aly/Ref antibody [11G5] from Abcam

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