Anti-MC4 Receptor (extracellular) Antibody AMR-024 from Alomone Labs, Ltd.

Product Specs
ItemAnti-MC4 Receptor (extracellular) Antibody
CompanyAlomone Labs, Ltd.
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberAMR-024
Brand/TrademarkAlomone Labs Ltd
Domain/Region/Terminusextracellular
ReactivityHuman (Tested);Mouse (Tested);Rat (Tested)
ApplicationsICC, IF, IHC, LCI, WB
FormatReconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3., Lyophilized Powder
Conjugate/TagUnconjugated
HostRabbit
Quantity1 X 25 mcl, 1 X 50 mcl, 1 X 0.2 ml
ClonalityPolyclonal
Antibody TypePrimary
Concentration08 mg/ml
PurityAffinity purified on immobilized antigen
IsotypeIgG
ImmunogenSynthetic peptide
Gene NameMC4R
TargetMelanocortin Receptor 4
ValidationAs per applications, See images, contact for clarifications
NCBI Full Gene Namemelanocortin 4 receptor
NCBI Gene AliasesBMIQ20
pH RangepH 7.4

Specifications/Features

starting price for North American orders, for exact pricing view product page

Sequence

(C)HRGMHTSLHLWNRSS, corresponding to amino acid residues 6-20 of human MC4R

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Alomone Labs, Ltd.

PO Box 4287

Jerusalem 91042

Israel

Phone: +972-2-587-2202
+972-2-587-1101

Company Profile

Website: http://www.alomone.com/

(1) Lateral septum as a melanocortin downstream site in obesity developmentCell ReportsMay 11, 2023Yuanzhong Xu, Zhiying Jiang, Hongli Li, Jing Cai, Yanyan Jiang, Joshua Ortiz-Guzman, Yong Xu, Benjamin R. Arenkiel, Qingchun TongABclonal, A7677), VMAT2 (rabbit, Phoenix Pharmaceuticals, H-V008), or Mc4R (rabbit, Alomone labs, Cat#AMR-024). All brain sections were incubated with the primary antibodies overnight at room temperature following

(2) Reduced MC4R signaling alters nociceptive thresholds associated with red hairScience AdvancesApril 2, 2021Kathleen C. Robinson et al.PBS-X for 30 min, a mixture of primary antibodies rabbit anti-MC4R at 1:250 (Alomone Labs, catalog no. AMR-024, RRID:AB_2039980) and guinea pig anti-OPRM1 at 1:500 (Abcam, catalog no. ab64746, RRID:AB_ 1141103)

(3) Reduction in Nesfatin-1 Levels in the Cerebrospinal Fluid and Increased Nigrostriatal Degeneration Following Ventricular Administration of Anti-nesfatin-1 Antibody in MiceFrontiers in neuroscienceJanuary 1, 2021Chen H, Li X, Ma H, Zheng W, Shen X.

(4) Activation of the ARC(POMC)→MeA Projection Reduces Food IntakeFrontiers in neural circuitsJanuary 1, 2020Kwon E, Jo YH.sc-57021), sheep anti-α-MSH (1:10,000, Millipore, cat# AB5087), rabbit anti-MC4R (1:250, Alomone labs, cat# AMR-024), and rabbit anti-ER-α (1:40,000, Millipore, cat# 06-935) antibodies for 72 h at cold room. The sections were

(5) Central Amygdala Circuits Mediate Hyperalgesia in Alcohol-Dependent RatsThe Journal of NeuroscienceSeptember 5, 2018Elizabeth M. Avegno, Thomas D. Lobell, Christy A. Itoga, Brittni B. Baynes, Annie M. Whitaker, Marcus M. Weera, Scott Edwards, Jason W. Middleton, Nicholas W. Gilpinnonfat milk at 4°C, then incubated in primary antibody (rabbit anti-MC4R [1:1000; Alomone Labs; catalog #AMR-024; RRID:AB_2039980] and mouse anti-␤-tubulin [1:500,000; Santa Cruz Biotechnology; catalog #sc-53140;

(6) ACTH Prevents Deficits in Fear Extinction Associated with Early Life SeizuresFrontiers in neurologyJanuary 1, 2016Massey AT, Lerner DK, Holmes GL, Scott RC, Hernan AE.

(7) Melanocortin 4 Receptor and Dopamine D2 Receptor Expression in Brain Areas Involved in Food IntakeEndocrinology and metabolism (Seoul, Korea)December 1, 2015Yoon YR, Baik JH.Sections were then incubated with primary rabbit polyclonal anti-MC4R antibody (1:100, catalog no. AMR-024, Alomone Labs, Jerusalem, Israel) in blocking solution overnight at 4°C with slow shaking. Subsequently,

(8) Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase A-dependent mechanismThe Journal of neuroscience : the official journal of the Society for NeuroscienceJanuary 9, 2013Shen Y, Fu WY, Cheng EY, Fu AK, Ip NY.

(9) BMP receptor 1A regulates development of hypothalamic circuits critical for feeding behaviorThe Journal of neuroscience : the official journal of the Society for NeuroscienceNovember 28, 2012Peng CY, Mukhopadhyay A, Jarrett JC, Yoshikawa K, Kessler JA.

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