Anti-PPM1A antibody [p6c7] ab14824 from Abcam

Product Specs
ItemAnti-PPM1A antibody [p6c7]
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab14824
Antibody TypePrimary
ApplicationsImmunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
HostMouse, Nude mouse
ClonalityMonoclonal
Quantity100 UL
IsotypeIgG2b
Clonep6c7
Conjugate/TagUnconjugated
Concentration1 mg/ml
Gene NamePPM1A
ValidationKnockOut Validated
ReactivityHuman, Mouse
TargetPPM1A

Add to Compare List

Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Protein phosphatase PPM1A inhibition attenuates osteoarthritis via regulating TGF-β/Smad2 signaling in chondrocytesJCI insightFebruary 8, 2023Ge Q, Shi Z, Zou KA, Ying J, Chen J, Yuan W, Wang W, Xiao L, Lin X, Chen D, et al.(Abcam, catalog ab34712; 1:500, IF), PPM1A (Bioss, catalog bs-4162R; 1:300, IHC; and Abcam, catalog ab14824; 1:100, IF), MMP-13 (Abcam, catalog ab39012; 1:300, IHC), Adamts-5 (Bioss, catalog bs-3573R; 1:200,

(2) Astrocytic NDRG2-PPM1A interaction exacerbates blood-brain barrier disruption after subarachnoid hemorrhageScience advancesSeptember 30, 2022Feng D, Zhou J, Liu H, Wu X, Li F, Zhao J, Zhang Y, Wang L, Chao M, Wang Q, et al.anti-p-Smad2(Ser465/467)/Smad3(Ser423/425) (1:200; Cell Signaling Technology, 8828), anti-PPM1A (1:200; Abcam, ab14824), and anti–laminin α2 (1:200; Sigma-Aldrich, L0663). Samples were then incubated with the secondary

(3) lncRNA TSPEAR-AS2, a Novel Prognostic Biomarker, Promotes Oral Squamous Cell Carcinoma Progression by Upregulating PPM1A via Sponging miR-487a-3pDisease MarkersJuly 17, 2021Yi-chao Xia, Jun Cao, Jing Yang, Ying Zhang, Yong-sheng Limilk for 1 h. Then, the membrane was incubated with primary antibodies including anti-PPM1A (Cat no. ab14824, Abcam) and anti-GAPHD (Cat no. ab8245; Abcam) at 4°C throughout the night and with horseradish peroxidase-

(4) Ubiquitin specific peptidase 49 inhibits renal fibrosis through protein phosphatase magnesium-dependent1A-mediated Smad2/3 pathwayArchives of Medical ScienceMarch 21, 2021Wenrui Liu, Yue Guo, Jie Chen, Lianxiang Duan, Chuanfu Zhang, Jing Hu, Baojuan Zhou, Jianrao LuThe 118 membrane was incubated with the primary antibody USP49 (1:1000, ab127574, Abcam, UK), 119 PPM1A (1:1000, ab14824, Abcam), vimentin (1:500, ab8978, Abcam), α-SMA (1:1000, 120 ab124964, Abcam), E-cadherin (1:500,

(5) MiR-1165-3p Suppresses Th2 Differentiation via Targeting IL-13 and PPM1A in a Mouse Model of Allergic Airway InflammationAllergy, asthma & immunology researchSeptember 1, 2020Wang Z, Ji N, Chen Z, Sun Z, Wu C, Yu W, Hu F, Huang M, Zhang M.Danvers, MA, USA), anti-GATA3 (ab106625, Abcam, Cambridge, England), anti-T-bet (ab91109, Abcam), anti-PPM1a (ab14824, Abcam), and Phospho-Stat Antibody Sampler Kit (9914, Cell Signaling Technology), Stat antibody sampler kit

(6) TGF-β1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAMEBioMedicineApril 1, 2019Wang K, Fang S, Liu Q, Gao J, Wang X, Zhu H, Zhu Z, Ji F, Wu J, Ma Y, et al.ab109484), anti-MAT1A (Abcam, ab174687), anti-COL1A1 antibody (Novus, NBP1-30054), anti-PPM1A/PP2Cα (Abcam, ab14824), anti-RELA/p65 (CST, 8242), anti-phospho-RELA/ p-p65 (Ser536, CST, 3033) anti-TGF-β1 (Abcam, ab92486)

(7) Infection Reveals a Modification of SIRT2 Critical for Chromatin AssociationCell reportsApril 24, 2018Pereira JM, Chevalier C, Chaze T, Gianetto Q, Impens F, Matondo M, Cossart P, Hamon MA.anti-EF-Tu (Archambaud et al., 2005); mouse: anti-α-tubulin (Sigma, T6074), anti-PPM1A [p6c7] (Abcam, ab14824), anti-NFκB p65 (F-6) (Santa Cruz Biotechnology, sc-8008), and anti-FLAG M2 (F3165, Sigma). Cell Culture,

(8) Ppm1b negatively regulates necroptosis through dephosphorylating Rip3Nature cell biologyApril 1, 2015Chen W, Wu J, Li L, Zhang Z, Ren J, Liang Y, Chen F, Yang C, Zhou Z, Su SS, et al.full-length human Ppm1b-L as the antigen. Anti-human Rip3 (ab72106, dilution 1:1,000) and anti-Ppm1a (ab14824, dilution 1:1,000) antibodies were from Abcam. Anti-Flag (F7425, dilution 1:500), Myc (A7470, agarose

(9) Protein phosphatase 2C-alpha knockdown reduces angiotensin II-mediated skeletal muscle wasting via restoration of mitochondrial recycling and functionSkeletal MuscleDecember 1, 2014Alexander Michael Tabony, Tadashi Yoshida, Sergiy Sukhanov, Patrice Delafontainegenes), and SDS-PAGE/western blotting. Primary antibodies utilized were as follows: from Abcam: PPM1A (ab14824), PP2C alpha + PP2C beta (ab27267), PGC-1α (ab54481), Fbxo32 (ab74023), MuRF1 (ab77577), Mitofusin-1,

(10) Role of Protein Phosphatase Magnesium-Dependent 1A and Anti-Protein Phosphatase Magnesium-Dependent 1A Autoantibodies in Ankylosing SpondylitisArthritis & RheumatologyOctober 8, 2014Yong-Gil Kim, Dong Hyun Sohn, Xiaoyan Zhao, Jeremy Sokolove, Tamsin M. Lindstrom, Bin Yoo, Chang-Keun Lee, John D. Reveille, Joel D. Taurog, William H. Robinson

(11) Phosphatase PPM1A negatively regulates P-TEFb function in resting CD4(+) T cells and inhibits HIV-1 gene expressionRetrovirologyDecember 1, 2012Sona Budhiraja, Rajesh Ramakrishnan, Andrew P Rice

(12) Dihydrosphingosine 1-phosphate has a potent antifibrotic effect in scleroderma fibroblasts via normalization of phosphatase and tensin homolog levelsArthritis and rheumatismJuly 1, 2010Shizhong Bu, Yoshihide Asano, Andreea Bujor, Kristin Highland, Faye Hant, Maria Trojanowska

(13) Hypoxia-activated Smad3-specific dephosphorylation by PP2AThe Journal of biological chemistryFebruary 5, 2010Pekka T Heikkinen, Marika Nummela, Suvi-Katri Leivonen, Jukka Westermarck, Caroline S Hill, Veli-Matti Kähäri, Panu M Jaakkola

(14) TGF-beta signalling is regulated by Schnurri-2-dependent nuclear translocation of CLIC4 and consequent stabilization of phospho-Smad2 and 3Nature cell biologyJune 1, 2009Anjali Shukla, Mariam Malik, Christophe Cataisson, Yan Ho, Travis Friesen, Kwang S Suh, Stuart H Yuspa

(15) PPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activationCellular signallingJanuary 1, 2009Wenjing Sun, Yang Yu, Gianpietro Dotti, Tao Shen, Xiaojie Tan, Barbara Savoldo, Amy K Pass, Meijin Chu, Dekai Zhang, Xiongbin Lu, Songbin Fu, Xia Lin, Jianhua Yang

(16) Opposite effects of dihydrosphingosine 1-phosphate and sphingosine 1-phosphate on transforming growth factor-beta/Smad signaling are mediated through the PTEN/PPM1A-dependent pathwayThe Journal of biological chemistryJuly 11, 2008Shizhong Bu, Bagrat Kapanadze, Tien Hsu, Maria Trojanowska

(17) PPM1A functions as a Smad phosphatase to terminate TGFbeta signalingCellJune 2, 2006Xia Lin, Xueyan Duan, Yao-Yun Liang, Ying Su, Katharine H Wrighton, Jianyin Long, Min Hu, Candi M Davis, Jinrong Wang, F Charles Brunicardi, Yigong Shi, Ye-Guang Chen, Anming Meng, Xin-Hua Feng

Be the First to Write a Review!

Anti-PPM1A antibody [p6c7] from Abcam

Abcam

Citations (17)

Reviews

Anti-PPM1A antibody [p6c7] from Abcam

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map