Anti-UQCRC2 antibody [13G12AF12BB11] ab14745 from Abcam

Product Specs
ItemAnti-UQCRC2 antibody [13G12AF12BB11]
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab14745
Antibody TypePrimary
ApplicationsFlow Cytometry, Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
IsotypeIgG1
HostMouse, Nude mouse
Quantity100 UG
ClonalityMonoclonal
Clone13G12AF12BB11
Conjugate/TagUnconjugated
Concentration1 mg/ml
Gene NameUQCRC2
ReactivityHuman
TargetUQCRC2

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Melatonin Alleviates the Impairment of Muscle Bioenergetics and Protein Quality Control Systems in Leptin-Deficiency-Induced ObesityAntioxidants (Basel)November 3, 2023Yaiza Potes, Andrea Díaz-Luis, Juan C. Bermejo-Millo, Zulema Pérez-Martínez, Beatriz de Luxán-Delgado, Adrian Rubio-González, Iván Menéndez-Valle, José Gutiérrez-Rodríguez, Juan J. Solano, Beatriz Caballero, et al.CI-20 (NDUFB8) (ab110242, Abcam, Cambridge, UK); CII-30 (SDHB) (ab14714, Abcam); CIII-Core II (UQCRC2) (ab14745, Abcam); CIV-I (MTCO1) (ab14705, Abcam); CV-a (ATP5A) (ab14748, Abcam); cyclophilin D (ab110324 (MSA04),

(2) Tissue-specific differences in the assembly of mitochondrial Complex I are revealed by a novel ENU mutation in ECSITCardiovascular ResearchOctober 16, 2023Thomas Nicol, Sara Falcone, Andrew Blease, Pratik Vikhe, Gabriele Civiletto, Saleh Salman Omairi, Carlo Viscomi, Ketan Patel, Paul K Potter,1:10 000,70 TOM20,Rabbit poly,"Abcam, Cambridge, UK",ab199641,1:1000,16 UQCRC2,Mouse mono,"Abcam, Cambridge, UK",ab14745,1:1000,49 VDAC,Rabbit poly,"Abcam, Cambridge, UK",ab15895,1:1000,31 α-TUBULIN,Rabbit mono,"Abcam,

(3) Development of a novel in vitro model to study the modulatory role of the respiratory complex I in macrophage effector functionsPLOS ONESeptember 19, 2023Pablo Serrano-Lorenzo, Dino Gobelli, Rocío Garrido-Moraga, María J. Esteban-Amo, José R. López-López, Antonio Orduña, Miguel A. de la Fuente, Miguel A. Martín, María SimarroThermo Fisher Scientific), anti-NDUFV1 (sc-100566, Santa Cruz Biotechnology), anti-SDHA (ab14715, Abcam), and anti-UQCR2 (ab14745, Abcam). Immunoreactive bands were detected with an Amersham ECL Prime Reagent (GE- Healthcare) in a

(4) Systemic gene therapy using an AAV44.9 vector rescues a neonatal lethal mouse model of propionic acidemiaMolecular Therapy - Methods & Clinical DevelopmentSeptember 14, 2023Randy J. Chandler, Giovanni Di Pasquale, Eun-Young Choi, David Chang, Stephanie N. Smith, Jennifer L. Sloan, Victoria Hoffmann, Lina Li, John A. Chiorini, Charles P. Vendittiantibodies were used for detection of PCCA (Abcam, ab187686) at a dilution of 1:1,000; UQCRC2 (Abcam, ab14745) at a dilution of 1:2,000; GAPDH (Proteintech, catalog number 60004-1-Ig) at a dilution of 1:10,000;

(5) Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagyExperimental & molecular medicineAugust 1, 2023Jang HJ, Lee YH, Dao T, Jo Y, Khim KW, Eom HJ, Lee JE, Song YJ, Choi SS, Park K, et al.anti-β-actin (GTX629630, Genetex, Irvine, CA), anti-SDHB (ab14714, Abcam, Cambridge, UK), anti-UQCRC2 (ab14745, Abcam, Cambridge, UK), anti-ATP5A (ab14748, Abcam, Cambridge, UK), anti-PINK1 (BC100-494, Novus Biologicals,

(6) Fatty acid oxidation organizes mitochondrial supercomplexes to sustain astrocytic ROS and cognitionNature MetabolismJuly 17, 2023Brenda Morant-Ferrando, Daniel Jimenez-Blasco, Paula Alonso-Batan, Jesús Agulla, Rebeca Lapresa, Dario Garcia-Rodriguez, Sara Yunta-Sanchez, Irene Lopez-Fabuel, Emilio Fernandez, Peter Carmeliet, et al.(ab56783; Abcam), anti-NDUFS1 (1/500) (sc-50132; Santa Cruz Biotechnology), anti-UQCRC2 (1/1,000) (ab14745; Abcam), anti-GFAP (1/500) (G6171; Sigma), anti-NDUFB8 (1/1,000) (ab110242; Abcam), anti-NDUFA9 (1/1,000)

(7) Expanding DdCBE-mediated targeting scope to aC motif preference in ratMolecular therapy. Nucleic acidsJune 13, 2023Qi X, Tan L, Zhang X, Jin J, Kong W, Chen W, Wang J, Dong W, Gao L, Luo L, et al.1:1,000); anti-SDHB (Abcam ab14714; 1:200); anti-CYB (Proteintech 55090-1-AP; 1:1,000); anti-UQCRC2 (Abcam ab14745; 1:1,000); anti-ATP8 (ABclonal A17890, 1:1,000); anti-ATP5A (Abcam ab176569; 1:1,000); anti-COX IV (Proteintech

(8) Hippocampal versus cortical deletion of cholinergic receptor muscarinic 1 in mice differentially affects post-translational modifications and supramolecular assembly of respiratory chain-associated proteins, mitochondrial ultrastructure, and respiration: implications in Alzheimer’s diseaseFrontiers in Cell and Developmental BiologyMay 24, 2023Mohammad Golam Sabbir, Mamiko Swanson, Robert C. Speth, Benedict C. AlbensiAnti-NDUFB8, Anti-SDHB, Anti-UQCRC2, Anti-MT-CO1, and Anti-ATP5A antibodies","MS604-300 (ab110242, ab14714, ab14745, ab14705, and ab14748, respectively)",Abcam,Monoclonal,K2342 "OXPHOS-human containing a cocktail of

(9) Mitochondrial supercomplex assembly regulates metabolic features and glutamine dependency in mammalian cellsTheranosticsMay 21, 2023Kun Zhang, Linjie Chen, Bo Wang, Deyu Chen, Xianglai Ye, Xinyu Han, Quan Fang, Can Yu, Jia Wu, Sihan Guo, et al.1:1000, Abcam), anti-NDUFB6 (ab110244; 1:1000, Abcam), anti-SDHA (ab14715; 1:1000, Abcam), anti-UQCRC2 (ab14745; 1:1000, Abcam), or anti-ATP synthase subunit-α (ab14748; 1:1000, Abcam). The secondary antibodies used

(10) ATAD3A-related pontocerebellar hypoplasia: new patients and insights into phenotypic variabilityOrphanet Journal of Rare DiseasesApril 24, 2023Martina Skopkova, Hana Stufkova, Vibhuti Rambani, Viktor Stranecky, Katarina Brennerova, Miriam Kolnikova, Michaela Pietrzykova, Miloslav Karhanek, Lenka Noskova, Marketa Tesarova, et al.1:2,000), NDUFB6 (ab 110,244, Abcam, dilution 1:4,000), SDHA (ab14715, Abcam, dilution 1:20,000), UQCRC2 (ab14745, Abcam, dilution 1:20,000), COX1 (ab14705, Abcam, dilution 1:10,000), COX2 (ab110258, Abcam, dilution

(11) A conditional knockout rat resource of mitochondrial protein-coding genes via a DdCBE-induced premature stop codonScience advancesApril 14, 2023Tan L, Qi X, Kong W, Jin J, Lu D, Zhang X, Wang Y, Wang S, Dong W, Shi X, et al.anti-SDHB (1:200; ab14714, Abcam), anti-CYTB (1:2000; 55090-1-AP, Proteintech), anti-UQCRC2 (1:1000; ab14745, Abcam), anti-COX1 (1:1000; A17889, ABclonal), anti-COX2 (1:1000; 55070-1-AP, Proteintech), anti-COX3

(12) A neuron-specific Isca1 knockout rat developments multiple mitochondrial dysfunction syndromesAnimal models and experimental medicineApril 1, 2023Sheng H, Lu D, Qi X, Ling Y, Li J, Zhang X, Dong W, Chen W, Gao S, Gao X, et al.ab110246" SDHB,1:200,"Abcam, ab14714" Aconitase 2,1:1000,"Abcam, ab110321" UQCRC2,1:1000,"Abcam, ab14745" COX IV,1:1000,"Abcam, ab16056" HRP‐conjugated anti‐rabbit IgG,1:10 000,"ZXGB‐Bio, ZB‐2301" HRP‐conjugated

(13) Novel ELAC2 Mutations in Individuals Presenting with Variably Severe Neurological Disease in the Presence or Absence of CardiomyopathyLife (Basel, Switzerland)February 4, 2023Cafournet C, Zanin S, Guimier A, Hully M, Assouline Z, Barcia G, de Lonlay P, Steffann J, Munnich A, Bonnefont JP, et al.(ab110240, Abcam, Cambridge, UK) for Complex I, anti-SDHA (ab14715, Abcam) for Complex II, anti-UQCRC2 (ab14745, Abcam) for Complex III, anti-cytochrome c oxidase (COXIV) (11242–1-AP, Proteintech, Manchester, UK)

(14) Novel Homozygous Variant in COQ7 in Siblings With Hereditary Motor NeuropathyNeurology. GeneticsFebruary 1, 2023Smith IC, Pileggi CA, Wang Y, Kernohan K, Hartley T, McMillan HJ, Sampaio ML, Melkus G, Woulfe J, Parmar G, et al.(459200; Thermo Fisher Scientific), complex III (CIII; ubiquinol‐cytochrome c reductase core protein II) (Ab14745; MitoSciences [Abcam, Cambridge, United Kingdom]), complex IV (CIV; subunit I) (459600; Thermo Fisher Scientific

(15) A FRET-based respirasome assembly screen identifies spleen tyrosine kinase as a target to improve muscle mitochondrial respiration and exercise performance in miceNature communicationsJanuary 25, 2023Kobayashi A, Azuma K, Takeiwa T, Kitami T, Horie K, Ikeda K, Inoue S.rabbit monoclonal ATP5A antibody (ab176569, 1:1000 dilution) and mouse monoclonal UQCRC2 antibody (ab14745, 1:1000 dilution) were purchased from Abcam (Cambridge, UK). Mouse monoclonal FP70 antibody (clone:

(16) A library of base editors for the precise ablation of all protein-coding genes in the mouse mitochondrial genomeNature Biomedical EngineeringDecember 5, 2022Pedro Silva-Pinheiro, Christian D. Mutti, Lindsey Van Haute, Christopher A. Powell, Pavel A. Nash, Keira Turner, Michal Minczuk1:1,000 (Abcam, ab110242); mouse anti-SDHB, 1:2,000 (Abcam, ab14714); mouse anti-UQRC2, 1:1,000 (Abcam, ab14745); mouse anti-COX IV, 1:1,000 (Abcam, ab14744) and mouse anti-ATP5A, 1:1,000 (Abcam, ab14748) all diluted

(17) HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemiaNature communicationsOctober 16, 2022Dong Q, Xiu Y, Wang Y, Hodgson C, Borcherding N, Jordan C, Buchanan J, Taylor E, Wagner B, Leidinger M, et al.SDHB (ab14714,1:800 dilution), SDHC (ab155999,1:800 dilution), SDHD (ab189945,1:800 dilution), UQCRC2 (ab14745,1:800 dilution), MTCO1 (ab14705,1:800 dilution), ATP5B (ab14730,1:800 dilution) (all from Abcam), DDK/FLAG

(18) COX7A2L genetic variants determine cardiorespiratory fitness in mice and humanNature metabolismOctober 1, 2022Benegiamo G, Bou Sleiman M, Wohlwend M, Rodríguez-López S, Goeminne LJE, Laurila PP, Klevjer M, Salonen MK, Lahti J, Jha P, et al.(Abcam, ab110413, 1:1,000 dilution), anti-NDUFS3 (Abcam, ab14711, 1:2,000 dilution), anti-UQCRC2 (Abcam, ab14745, 1:10,000 dilution), anti-MTCO1 antibody (Abcam, ab14705, 1:1,000 dilution) and anti-COX7A2L antibody

(19) Human TRUB1 is a highly conserved pseudouridine synthase responsible for the formation of Ψ55 in mitochondrial tRNAAsn, tRNAGln, tRNAGlu and tRNAProNucleic acids researchSeptember 9, 2022Jia Z, Meng F, Chen H, Zhu G, Li X, He Y, Zhang L, He X, Zhan H, Chen M, et al.ND4L(PA5-68242)], Abcam [ND1(ab74257), ND3(ab170681), ND5(ab92624), TOMM20/TOM20(ab56783), SDHB(ab14714), UQCRC2(ab14745) and TUBULIN (ab6046)], Novus [ND4(NBP2-47365)], ABclonal [NDUFA1(A20940) and NDUFA10(A10123)] and Proteintech

(20) Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesityEBioMedicineSeptember 1, 2022Pileggi CA, Blondin DP, Hooks BG, Parmar G, Alecu I, Patten DA, Cuillerier A, O'Dwyer C, Thrush AB, Fullerton MD, et al.RRID:AB_2532231, 1:20000), complex III ubiquinol‐cytochrome c reductase core protein II, (UQCRC2; Abcam, ab14745, RRID: AB_2213640, 1:2000); complex IV (subunit I) (MTCO1; Thermofisher, 459600, RRID:AB_2532240, 1:2000),

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Anti-UQCRC2 antibody [13G12AF12BB11] from Abcam

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Anti-UQCRC2 antibody [13G12AF12BB11] from Abcam

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