Fig 1: Receiver operating characteristics of five proteins that qualified from protein profiling in the training cohort. (A) Leptin, and (B) osteopontin met the minimum requirement for a prognostically useful test according to our definition (i.e., lower bound of AUC 95% CI > 0.5). (C) Progranulin, (D) tenascin C, and (E) DLL1 did not meet the minimum requirement. AUC, area under the curve. CI, confidence interval