Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of MACC1 in human serum, plasma, tissue homogenates.
Target Information: MACC1 is a key regulator of the hepatocyte growth factor (HGF\, MIM 142409)-HGF receptor (HGFR, or MET\, MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009]