Fig 2: Effusion CDC42 and IL-4 levels were positively associated with effusion viscosity and hearing loss degree in OME patients. Comparison of effusion CDC42 (A), IL-4 (B), and IFN-? (C) levels between patients with serous effusion and patients with mucoid effusion. Comparison of effusion CDC42 (D), IL-4 (E), and IFN-? (F) levels among patients with slight, mild, and moderate hearing loss degrees. CDC42, cell division cycle 42; IL-4, interleukin-4; OME, otitis media with effusion; IFN-?, interferon-gamma

Fig 3: Serum CDC42 and IL-4 levels were up-regulated in OME patients than those in controls. The comparison of serum CDC42 level between OME patients and controls (A) and its differentiating value of OME from controls (B). The comparison of serum IL-4 level between OME patients and controls (C) and its differentiating value of OME from controls (D). The comparison of serum IFN-? level between OME patients and controls (E) and its differentiating value of OME from controls (F). CDC42, cell division cycle 42; IL-4, interleukin-4; OME, otitis media with effusion; IFN-?, interferon-gamma

Fig 4: Effusion CDC42 level was positively related to IL-4 level in OME patients and controls. The association of effusion CDC42 level with effusion IL-4 level (A) and effusion IFN-? level (B) in OME patients. The association of effusion CDC42 level with effusion IL-4 level (C) and effusion IFN-? level (D) in controls. CDC42, cell division cycle 42; IL-4, interleukin-4; OME, otitis media with effusion; IFN-?, interferon-gamma