Fig 1: Changes in the oxidant/antioxidant markers in the lung of saline-instilled animals (Control), silica-instilled non-treated animals (Model), and EGCG-treated silica-instilled animals (EGCG) after 14 days (14d) or 28 days (28d) of the treatment delivery. Abbreviations: TAC: total antioxidant capacity; SOD: superoxide dismutase; Nrf2: nuclear factor erythroid-derived 2-like factor 2; HO-1: heme oxygenase; NQO-1: NAD(P)H:quinone oxidoreductase-1; NLRP3: nucleotide-binding and oligomerization domain-like receptor. For statistical differences among the groups: * p < 0.05 for Model14d vs. Control14d; + p < 0.05 and ++ p < 0.01 for EGCG14d vs. Model14d; # p < 0.05 for Model28d vs. Control28d; & p < 0.05 and && p < 0.01 for EGCG28d vs. Model28d.
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