Corning® 384-well Black/Clear Round Bottom Ultra-Low Attachment Spheroid Microplate, with Lid, Sterile from Corning Life Sciences

Product Specs
ItemCorning® 384-well Black/Clear Round Bottom Ultra-Low Attachment Spheroid Microplate, with Lid, Sterile
CompanyCorning Life Sciences
Price Pricing Info Supplier Page View Company Product Page
Catalog Number4516
Quantity1 / Pk
Format384-well
VolumeRecommended Working Volume: 20-80 µL, Recommended Medium Well Volume: 20 - 90 µL, Well Volume: 90 µL
AreaCell Growth Area: 0.06 cm² (approx.)
Brand/TrademarkCorning®
SterilitySterile
Type384 Well Microplates

Specifications/Features

Plate Feature: Standard

Lids Included: Yes

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Corning Life Sciences

836 North Street

Building 300 Suite 3401

Tewksbury, MA 01876

United States

Phone: (978) 442-2200
Phone: (800) 492-1110

Email: clscustserv@corning.com

Company Profile

Website: www.corning.com/lifesciences

(1) Tyrosine kinase receptor B attenuates liver fibrosis by inhibiting TGF-β/SMAD signalingHepatologyNovember 1, 2023Yu Song, Jiayi Wei, Rong Li, Ruifeng Fu, Pei Han, Heming Wang, Guangcong Zhang, Shuyu Li, Sinuo Chen, Zhiyong Liu, et al.construction 3D liver spheroids were constructed with HepG2 and LX2 cells in 384-well Corning microplates (Cat. 4516). Both cell types were assembled with DNA Origamis in a ratio of 10:1 (50,000 cells per spheroid). Spheroids

(2) Optimizing Precision Medicine for Breast Cancer Brain Metastases with Functional Drug Response AssessmentCancer Research CommunicationsJune 21, 2023Aki Morikawa, Jinju Li, Peter Ulintz, Xu Cheng, Athena Apfel, Dan Robinson, Alex Hopkins, Chandan Kumar-Sinha, Yi-Mi Wu, Habib Serhan, et al.analysis (24). Drug Testing Cells were screened in 384-well ultra-low attachment plates (Corning, 4516 or S-Bio, MS-9384WZ) in singlicate or duplicate, 7-point dose–response format. Cells were plated in

(3) Multimodal characterization of murine gastruloid developmentCell Stem CellJune 1, 2023Simon Suppinger, Marietta Zinner, Nadim Aizarani, Ilya Lukonin, Raphael Ortiz, Chiara Azzi, Michael B. Stadler, Stefano Vianello, Giovanni Palla, Hubertus Kohler, et al.prepared and 20 μl per well were seeded into black, ultra-low attachment, round-bottom 384-well plates (4516, Corning) using the EL406 liquid handling robot (BioTek Instruments). All following medium changes were

(4) Discovery of a small molecule ligand of FRS2 that inhibits invasion and tumor growthCell Oncol (Dordr)April 1, 2023Karthiga Santhana Kumar, Cyrill Brunner, Matthias Schuster, Levi Luca Kopp, Alexandre Gries, Shen Yan, Simon Jurt, Kerstin Moehle, Dominique Bruns, Michael Grotzer, et al.Promega). 500 cells/25 µl were seeded in flat bottom (#781,091, Greiner bio-one) or U-low adhesion (#4516, Corning) 384-well plate, 24 h prior to treatment. Increasing concentrations of compounds are deposited

(5) Nitazoxanide inhibits acetylated KLF5-induced bone metastasis by modulating KLF5 function in prostate cancerBMC medicineFebruary 21, 2023Huang Q, Liu M, Zhang D, Lin BB, Fu X, Zhang Z, Zhang B, Dong JT.at 80-90% confluency were plated onto 384-well round bottom plates with ultra-low attachment (Cat #: 4516, Corning) at 500 cells per well in 80 μL medium. The plates were then centrifuged at 320 g for 4 min

(6) Iron Chelator VLX600 Inhibits Mitochondrial Respiration and Promotes Sensitization of Neuroblastoma Cells in Nutrition-Restricted ConditionsCancersJune 30, 2022Jakobsson AW, Kundu S, Guo J, Chowdhury A, Zhao M, Lindell E, Bergsten P, Swartling FJ, Sjöblom T, Zhang X.containing 1000 cells/50 μL was added to each well of the 384-well plates (Corning, Corning, NY, USA, # 4516). Plates were incubated for 4 days before drug exposure. Then, another 50 μL medium containing 2X VLX600

(7) Spatial proteomics finds CD155 and Endophilin-A1 as mediators of growth and invasion in medulloblastomaLife science allianceJune 1, 2022Capdeville C, Russo L, Penton D, Migliavacca J, Zecevic M, Gries A, Neuhauss SC, Grotzer MA, Baumgartner M.CellTiter-Glo 3D cell viability assay (#G9242, #G9682; Promega). 500 siRNA transfected cells/25 μl were seeded in U-low adhesion (#4516; Corning) 384-well plate. After 48 h, the CellTiter-Glo 3D reagent was added (volume/volume) following

(8) High-throughput formation and image-based analysis of basal-in mammary organoids in 384-well platesScientific reportsJanuary 10, 2022Lee S, Chang J, Kang SM, Parigoris E, Lee JH, Huh YS, Takayama S.96-, 384-, and 1536-well plates; well dimensions obtained from Corning Inc. (catalog numbers: 4515, 4516, and 4527, respectively) were used for calculation (see Supplementary Fig. S2). Real-time cell imaging

(9) Functional tissue-engineered microtissue formed by self-aggregation of cells for peripheral nerve regenerationStem cell research & therapyJanuary 10, 2022Zhang J, Li C, Meng F, Guan Y, Zhang T, Yang B, Ren Z, Liu X, Li D, Zhao J, et al.characterization of microtissues Fabrication of microtissues We used an ultra-low attachment microplate (4516; Corning) to construct microtissues. The microplates have 384 wells, the maximum volume of each well

(10) MEK is a promising target in the basal subtype of bladder cancerOncotargetNovember 3, 2020Nathan M. Merrill, Nathalie M. Vandecan, Kathleen C. Day, Phillip L. Palmbos, Mark L. Day, Aaron M. Udager, Sofia D. Merajver, Matthew B. Soellner“null” subtype. Drug screening Cells were screened in 384-well ultra-low attachment plates (Corning, 4516 or S-Bio, MS-9384WZ) in singlicate or duplicate, 7-point dose-response format. Cells were plated on

(11) Opposing Functions of BRD4 Isoforms in Breast CancerMolecular CellJune 1, 2020Shwu-Yuan Wu et al.(Corning™ 3764BC) for 2D monolayer culture or round-bottom ultra-low attachment microplates (Corning™ 4516) for 3D spheroid culture. After 5-day incubation at 37 °C in a 5% CO2 incubator, cell viability was

(12) Maximizing the Value of Cancer Drug Screening in Multicellular Tumor Spheroid Cultures: A Case Study in Five Head and Neck Squamous Cell Carcinoma Cell Lines.SLAS DiscoveryApril 1, 2020Stanton J. Kochanek, David A. Close, Daniel P. Camarco, Paul A. Johnstonpreviously described the production of MCTSs by seeding HNSCC cell lines into 384-well ULA-plates (cat. 4516; Corning, Tewksbury, MA).9,20,22,25 Briefly, 384-well ULA-plates were rehydrated by the addition of

(13) High Content Screening Characterization of Head and Neck Squamous Cell Carcinoma Multicellular Tumor Spheroid Cultures Generated in 384-Well Ultra-Low Attachment Plates to Screen for Better Cancer Drug LeadsASSAY and Drug Development TechnologiesJanuary 1, 2019Stanton J. Kochanek, David A. Close, Paul A. JohnstonUbottomed ultra-low attachment microtiter plates (ULA-plates; ª MARY ANN LIEBERT, INC. VOL. 17 Cat. No. 4516; Corning, Tewksbury, MA).22,29,34 Briefly, 384well ULA-plates were rehydrated by the addition of 50

(14) Scaffold-free generation of uniform adipose spheroids for metabolism research and drug discoveryScientific ReportsDecember 1, 2018Aloysius J. Klingelhutz, Francoise A. Gourronc, Anna Chaly, David A. Wadkins, Anthony J. Burand, Kathleen R. Markan, Sharon O. Idiga, Meng Wu, Matthew J. Potthoff, James A. Ankrumuse of an ultra-low attachment round bottom spheroid plate (non-adherent 384 well microplate, Cat# 4516, Corning Inc., Corning NY). 500 pre-adipocytes were added to each well and cultured for 11 days in differentiation

(15) Evaluation of anticancer agents using patient-derived tumor organoids characteristically similar to source tissuesOncology ReportsJune 18, 2018Hirosumi Tamura et al.suspension was seeded in 384-well round-bottomed, ultra-low attachment spheroid microplates (cat. no. 4516; Corning Incorporated) using with a dispenser. At 24 h after seeding, F-PDOs were treated with 0.04-µl

(16) High-Content Screening Comparison of Cancer Drug Accumulation and Distribution in Two-Dimensional and Three-Dimensional Culture Models of Head and Neck CancerASSAY and Drug Development TechnologiesJanuary 1, 2018Feng Shan, David A. Close, Daniel P. Camarco, Paul A. JohnstonMCTSs in 384-well ULA plates has been previously described.34 Briefly, 384-well ULA plates (Cat. No. 4516; Corning) were rehydrated by the addition of 50 mL of serum-free DMEM to each well and incubation in

(17) High-Content Monitoring of Drug Effects in a 3D Spheroid ModelFrontiers in OncologyDecember 11, 2017Frédérique Mittler, Patricia Obeïd, Anastasia V. Rulina, Vincent Haguet, Xavier Gidrol, Maxim Y. BalakirevMicroplate,References,Format,Bottom1,Color2,Surface,Company Corning® Ultra-Low Attachment (ULA)3,"3474, 4520, 4515, 3830, 4516, 7007","96, 384",U,"c, b",Grafted hydrogel,Corning Life Sciences CELLSTAR® Cell-Repellent Surface,"650970,

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