AbNano™ VHH NaÏve Library from Abcore OP, LLC

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Abcore OP, LLC for
AbNano™ VHH NaÏve Library

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Description

AbNano™ VHH Naïve Library from Fortis Life Sciences® is a fully natural, single domain naïve library with source material from camelids and the antibodies displayed on monovalent phage. It is intended for research purposes only to aid in the discovery of antibodies intended for use as therapeutics, diagnostics, and research tools.

Why select the AbNano™ VHH Naïve Library
  • Save 18 weeks by starting with a prepared library that is ready to pan
  • To maximize diversity, this library was constructed from 103 naïve animals: 77 llamas and 26 alpacas. 1.51 x 1010 PBMC cells were collected and used for library construction and the total number of transformants for the library was 1.12 x 1010 cfu.
  • Naïve library can potentially bind a high number of targets compared to single-animal or single-target libraries
  • This fully natural library has higher diversity in framework regions than synthetic libraries
  • Lower affinity is ideal for the engineering of multispecific antibodies or self-assembling therapeutics
  • Data package included to support utility in identifying binders for several popular targets