Electronic von Frey Anesthesiometer from IITC Life Science

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ItemElectronic von Frey Anesthesiometer
CompanyIITC Life Science
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Catalog NumberAnesthesiometer
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IITC Life Science

23924 Victory Blvd.

Woodland Hills, California 91367

United States

Phone: 818-710-8843
Fax: 818-992-5185

Company Profile

Website: http://www.iitcinc.com

(1) Environmental enrichment reverses stress-induced changes in the brain-gut axis to ameliorate chronic visceral and somatic hypersensitivityNeurobiology of StressJanuary 1, 2024A. Orock, A.C. Johnson, E. Mohammadi, B. Greenwood-Van Meerveldelevated Plexiglas box with a wire mesh floor and allowed to acclimate for 10 min. The IITC 2390 series Electronic von Frey Anesthesiometer (IITC Life Science, Woodland Hills, CA) was then used to apply increasing force to the plantar region

(2) A-kinase anchoring protein 79/150 coordinates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor sensitization in sensory neuronsMol PainDecember 13, 2023Yan Zhang, Nathaniel A Jeskeh. Hyperalgesic priming behavior Mechanical withdrawal threshold of the rodent paw was measured with a plantar electronic von Frey Anesthesiometer (ALMEMO 2450 Ahlborn, IITC). Briefly, animals were placed in plastic boxes with a mesh floor surface

(3) Th1/17 polarization and potential treatment by an anti-interferon-γ DNA aptamer in Hunner-type interstitial cystitisiScienceNovember 17, 2023Yoshiyuki Akiyama, Kaori Harada, Jimpei Miyakawa, Karl J. Kreder, Michael A. O’Donnell, Maeda Daichi, Hiroto Katoh, Miyuki Hori, Kensuke Owari, Kazunobu Futami, et al.analysis As previously described,32 the sensory threshold of pelvic nociception was analyzed using an electronic von Frey anesthesiometer (VFA, IITC Inc. Life Science, Woodland Hills, CA, USA). In an initial experiment, this was performed

(4) Microglial P2X4 receptors are essential for spinal neurons hyperexcitability and tactile allodynia in male and female neuropathic miceiScienceNovember 17, 2023Damien Gilabert, Alexia Duveau, Sara Carracedo, Nathalie Linck, Adeline Langla, Rieko Muramatsu, Friedrich Koch-Nolte, François Rassendren, Thomas Grutter, Pascal Fossat, et al.lines in two distinct laboratories (Montpellier and Bordeaux) using electronic and manual Von Frey (Anesthesiometer, IITC Life Science, USA). For electronic Von Frey, calibrated tips were applied at the lateral plantar

(5) Polyherbal formulation PL02 alleviates pain, inflammation, and subchondral bone deterioration in an osteoarthritis rodent modelFrontiers in NutritionNovember 16, 2023Prabhat Upadhyay, Diya Kalra, Aishwarya Shrikant Nilakhe, Vijay Aggrawal, Sarika Guptameasured in response to increasing pressure stimuli applied by von frey hairs to the plantar surface (23). Electronic von Frey Anesthesiometer (IITC Inc. Life Science, California, United States) consists of rigid Supertips™ mounted on a sensitive

(6) Chronic Cannabigerol as an Effective Therapeutic for Cisplatin-Induced Neuropathic PainPharmaceuticals (Basel)October 11, 2023Rahul Nachnani, Diana E. Sepulveda, Jennifer L. Booth, Shouhao Zhou, Nicholas M. Graziane, Wesley M. Raup-Konsavage, Kent E. Vranacisplatin, termed “Baseline” and “Neuropathy”, respectively. Measurements were performed by using an electronic von Frey anesthesiometer (IITC Life Sciences Inc., Woodland Hills, CA, USA) exactly as previously described [10,11,14,22,38].

(7) An amygdala-to-cingulate cortex circuit for conflicting choices in chronic painCell ReportsOctober 1, 2023Kristina Valentinova, Mario A. Acuña, Niels R. Ntamati, Natalie E. Nevian, Thomas Neviancustom-made plexiglas enclosure (10 cm × 10 cm) placed on a grid. Mechanical allodynia was assessed using an electronic Von Frey anesthesiometer (IITC Life Science) by slowly applying pressure to the midplantar surface of the hind-paw with a Von

(8) Loss of ATP-sensitive channel expression and function decreases opioid sensitivity in a mouse model of type 2 diabetesbioRxivSeptember 13, 2023Cole Fisher, Kayla Johnson, Madelyn Moore, Amir Sadrati, Jody L. Janecek, Melanie L. Graham, Amanda H. Kleinwithdrawal thresholds were measured using electronic von Frey testing equipment (Electric von Frey Anesthesiometer, series 2390, Almemo® 2450 Ahlborn, IITC Life Science, Woodland Hills, CA). A probe was pressed into

(9) Nicotine Decreases Nerve Regeneration and Pain Behaviors via PTEN and Downstream Inflammation-Related Pathway in Two Rat Nerve Injury ModelseNeuroSeptember 1, 2023Fang Y, Zhang T, Li L, Chen S, Wang L, Tang J, Liao Y.20 cm) placed on a wire grid floor, and the plantar surface of the hindpaw was stimulated using an electronic von Frey anesthesiometer (Electronic von Frey 2390, IITC Life Science). The maximum force (g) was automatically recorded, and

(10) Hmgb1 Silencing in the Amygdala Inhibits Pain-Related Behaviors in a Rat Model of Neuropathic PainInternational journal of molecular sciencesJuly 26, 2023Presto P, Ji G, Ponomareva O, Ponomarev I, Neugebauer V.protocol”). 4.6.1. Mechanosensitivity Mechanical withdrawal thresholds were measured using a plantar electronic von Frey anesthesiometer (IITC Life Sciences, Woodland Hills, CA, USA) with the tip applied perpendicularly with increasing force

(11) Intrathecal administration of conditioned serum from different species resolves Chemotherapy-Induced neuropathic pain in mice via secretory exosomesBrain, behavior, and immunityJuly 1, 2023Buchheit T, Huh Y, Breglio A, Bang S, Xu J, Matsuoka Y, Guo R, Bortsov A, Reinecke J, Wehling P, et al.duration (seconds) of pain-like behaviors (lifting/licking). Mechanical pain in rats was assessed by an electronic von Frey Anesthesiometer (IITC Life Science Inc.). A hind paw was stimulated with increasing force (0–50 g) of a von Frey filament,

(12) Inflammatory pain affects alcohol intake in a dose-dependent manner in male rats in the intermittent access modelPAIN ReportsJuly 1, 2023Yolanda Campos-Jurado, Jose A. Morónmechanical hyperalgesia) induced by CFA injections, paw withdrawal thresholds (PWTs) were obtained using an electronic Von Frey Anesthesiometer (IITC Life Science, California, USA). Animals were placed in plexiglass chambers on top of a galvanized

(13) Electroacupuncture inhibits dendritic spine remodeling through the srGAP3-Rac1 signaling pathway in rats with SNLBiological ResearchMay 22, 2023Qiaoyun Wu, Chenchen Cai, Xinwang Ying, Yujun Zheng, Jiaying Yu, Xiaoxue Gu, Wenzhan Tu, Xinfa Lou, Guanhu Yang, Ming Li, et al.saline during the same time period. Mechanical withdrawal threshold (MWT) The MWT was examined by an electronic von Frey anesthesiometer (IITC Life Sciences, CA, USA) by an individual who was blinded to the experimental conditions, and the

(14) c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathyCell reportsApril 25, 2023Frezel N, Ranucci M, Foster E, Wende H, Pelczar P, Mendes R, Ganley RP, Werynska K, d'Aquin S, Beccarini C, et al.1 h before testing. Withdrawal thresholds were assessed by the stimulation of the hind paw with an electronic von Frey anesthesiometer (IITC, Woodland Hills, CA). Eight measurements were taken at an interval of 10 min between stimulations.

(15) Analgesic and potentiated photothermal therapy with ropivacaine-loaded hydrogelsTheranosticsApril 9, 2023Jiqian Zhang, Shasha Zhu, Mingxu Zhao, Mengni Zhou, Xiaoling Zhu, Xin Qing, Zhilai Yang, Pengfei Wei, Guoying Zhang, Weiling He, et al.timepoints. In brief, mice were placed in plastic cages with wire-net floors. The rigid tip of a 2450 series electronic Von Frey anesthesiometer was placed onto the plantar surface of the hind paw and pressed upward slowly until a withdrawal reflex

(16) Rodent behavior following a dural inflammation model with anti-CGRP migraine medication treatmentFrontiers in NeurologyFebruary 23, 2023Philip V. Reducha, Jesper P. Bömers, Lars Edvinsson, Kristian A. Haanesextend in other parts of the body (45). Mechanical allodynia was measured on the rats using an EVF Anesthesiometer (IITC, USA). EVF consist of a filament attached to a sensor of the EVF device. Individual rats were

(17) Hydrogel Encapsulation of Genome-Engineered Stem Cells for Long-Term Self-Regulating Anti-Cytokine TherapyGelsFebruary 20, 2023Kelsey H. Collins, Lara Pferdehirt, Leila S. Saleh, Alireza Savadipour, Luke E. Springer, Kristin L. Lenz, Dominic M. Thompson, Sara J. Oswald, Christine T. N. Pham, Farshid Guilakpressure-meter which consisted of a hand-held force transducer fitted with a 0.5 mm2 polypropylene tip (Electronic von Frey anesthesiometer, IITC Inc., Life Science Instruments, Woodland Hills, CA, USA) was used. A tip was applied against the

(18) Cancer aggravation due to persistent pain signals with the increased expression of pain-related mediators in sensory neurons of tumor-bearing miceMolecular BrainFebruary 3, 2023Kenichi Tanaka, Takashige Kondo, Michiko Narita, Takeru Muta, Sara Yoshida, Daisuke Sato, Yukari Suda, Yusuke Hamada, Takatsune Shimizu, Naoko Kuzumaki, et al.in diameter). Measurement of mechanical allodynia Mechanical allodynia was assessed by a plantar electronic von Frey Anesthesiometer (ALMEMO 2450 Ahlborn; IITC/Life Science). Briefly, a chip attached to the device was applied vertically

(19) Inhibitory Kcnip2 neurons of the spinal dorsal horn control behavioral sensitivity to environmental coldNeuronJanuary 4, 2023Gioele W. Albisetti, Robert P. Ganley, Francesca Pietrafesa, Karolina Werynska, Marília Magalhaes de Sousa, Rebecca Sipione, Louis Scheurer, Michael R. Bösl, Pawel Pelczar, Hendrik Wildner, et al.before CNO administration. Somatosensory tests Mechanical withdrawal thresholds were assessed using an electronic von Frey anesthesiometer (IITC) and the maximal force applied on the mouse paw was restricted to 6 g. Withdrawal latencies to

(20) Effects of low-level laser therapy on inflammatory symptoms in an arthritis rat modelJournal of Physical Therapy ScienceJanuary 1, 2023Seima Okita, Ryo Sasaki, Yasutaka Kondo, Junya Sakamoto, Yuichiro Honda, Minoru Okitaas the PPT17). To evaluate the mechanical paw withdrawal threshold (MPWT) of the right hind limb, an electronic von Frey anesthesiometer (IITC-2391, IITC Life Science Instruments, Los Angeles, CA, USA), adapted with a 0.5 mm2 contact area

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