Ko 143 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemKo 143
CompanyTocris Bioscience, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog Number3241/1
Quantity1 mg (also 10 mg)
Brand/TrademarkTocris, a Bio-Techne Brand
Purity0.99
Molecular Weight469.57
Molecule Name(3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester
FormulaC₂₆H₃₅N₃O₅
StorageStore at -20°C

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

(1) IGF-1 contributes to the expansion of melanoma-initiating cells through an epithelial-mesenchymal transition processOncotargetDecember 13, 2016Le Coz V, Zhu C, Devocelle A, Vazquez A, Boucheix C, Azzi S, Gallerne C, Eid P, Lecourt S, Giron-Michel J.

(3) Bioluminescent imaging of ABCG2 efflux activity at the blood-placenta barrierScientific reportsFebruary 8, 2016Kumar JS, Wei BR, Madigan JP, Simpson RM, Hall MD, Gottesman MM.

(4) ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to ChemotherapyCancer researchSeptember 15, 2015Morfouace M, Cheepala S, Jackson S, Fukuda Y, Patel YT, Fatima S, Kawauchi D, Shelat AA, Stewart CF, Sorrentino BP, et al.

(7) Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brainPharmacological researchSeptember 1, 2014Moreno-Sanz G, Barrera B, Armirotti A, Bertozzi SM, Scarpelli R, Bandiera T, Prieto JG, Duranti A, Tarzia G, Merino G, et al.

(8) Synthesis and structure-activity relationship studies of O-biphenyl-3-yl carbamates as peripherally restricted fatty acid amide hydrolase inhibitorsJournal of medicinal chemistryJuly 25, 2013Moreno-Sanz G, Duranti A, Melzig L, Fiorelli C, Ruda GF, Colombano G, Mestichelli P, Sanchini S, Tontini A, Mor M, et al.

(10) Erlotinib antagonizes ABC transporters in acute myeloid leukemiaCell cycle (Georgetown, Tex.)November 1, 2012Lainey E, Sébert M, Thépot S, Scoazec M, Bouteloup C, Leroy C, De Botton S, Galluzzi L, Fenaux P, Kroemer G.

(12) EZN-2208 (PEG-SN38) overcomes ABCG2-mediated topotecan resistance in BRCA1-deficient mouse mammary tumorsPloS oneJanuary 1, 2012Zander SA, Sol W, Greenberger L, Zhang Y, van Tellingen O, Jonkers J, Borst P, Rottenberg S.

(13) The ABC membrane transporter ABCG2 prevents access of FAAH inhibitor URB937 to the central nervous systemPharmacological researchOctober 1, 2011Moreno-Sanz G, Barrera B, Guijarro A, d'Elia I, Otero JA, Alvarez AI, Bandiera T, Merino G, Piomelli D.

Ko 143