Bay 11-7821 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemBay 11-7821
CompanyTocris Bioscience, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog Number1744/10
Quantity10 mg
Brand/TrademarkTocris, a Bio-Techne Brand
Purity0.99
Molecular Weight207.25
Molecule Name(2E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile
FormulaC₁₀H₉NO₂S
StorageStore at +4°C

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiationNature communicationsMay 13, 2021Lee HH, Wang YN, Yang WH, Xia W, Wei Y, Chan LC, Wang YH, Jiang Z, Xu S, Yao J, et al.inhibitors used were QNZ (30 nM, Selleck Chemical, #S4902), Bay 11-7821 (0.2 μM, Tocris Bioscience, #1744/10), GSK1120212 (1 nM, Apexbio Technology, #A301850), PD-0325901 (0.2 or 2 μM, Tocris Bioscience, #4192/10)

(2) Nonsaponin fraction of Korean Red Ginseng attenuates cytokine production via inhibition of TLR4 expressionJournal of ginseng researchApril 1, 2019Ahn H, Han BC, Kim J, Kang SG, Kim PH, Jang KH, So SH, Lee SH, Lee GS.

(3) TNFα induces tolerant production of CXC chemokines in colorectal cancer HCT116 cells via A20 inhibition of ERK signalingInternational immunopharmacologyJanuary 1, 2018Zhou X, An D, Liu X, Jiang M, Yuan C, Hu J.

(4) Targeting the NLRP3 inflammasome to attenuate spinal cord injury in miceJournal of neuroinflammationOctober 25, 2017Jiang W, Li M, He F, Zhou S, Zhu L.

(5) Nonsaponin fractions of Korean Red Ginseng extracts prime activation of NLRP3 inflammasomeJournal of ginseng researchOctober 1, 2017Han BC, Ahn H, Lee J, Jeon E, Seo S, Jang KH, Lee SH, Kim CH, Lee GS.

(6) β-Catenin and NF-κB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancerCell death and differentiationFebruary 1, 2015Jia D, Yang W, Li L, Liu H, Tan Y, Ooi S, Chi L, Filion LG, Figeys D, Wang L.

(7) CD31 is a key coinhibitory receptor in the development of immunogenic dendritic cellsProceedings of the National Academy of Sciences of the United States of AmericaMarch 25, 2014Clement M, Fornasa G, Guedj K, Ben Mkaddem S, Gaston AT, Khallou-Laschet J, Morvan M, Nicoletti A, Caligiuri G.

(8) Differential effects of the Toll-like receptor 2 agonists, PGN and Pam3CSK4 on anti-IgE induced human mast cell activationPloS oneJanuary 1, 2014Yu Y, Yip KH, Tam IY, Sam SW, Ng CW, Zhang W, Lau HY.

(9) Constitutive NF-kappaB activation confers interleukin 6 (IL6) independence and resistance to dexamethasone and Janus kinase inhibitor INCB018424 in murine plasmacytoma cellsThe Journal of biological chemistryAugust 12, 2011Yang Y, Groshong JS, Matta H, Gopalakrishnan R, Yi H, Chaudhary PM.

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Bay 11-7821

Bay 11-7821 from Tocris Bioscience, a Bio-Techne Brand

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Tocris Bioscience, a Bio-Techne Brand

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Bay 11-7821 from Tocris Bioscience, a Bio-Techne Brand

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