UNC0638 from Cayman Chemical

Product Specs
ItemUNC0638
CompanyCayman Chemical
Price Pricing Info Supplier Page View Company Product Page
Catalog Number10734
Quantity10 mg
Research AreaCancer, Epigenetics, Transcription, & Translation, Histone Methylation, Writers
FormatA crystalline solid
Molecular Weight509.7
Purity≥98%

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) H3K9 methylation drives resistance to androgen receptor–antagonist therapy in prostate cancerProceedings of the National Academy of SciencesMay 24, 2022Mehdi Baratchian et al.(Medivation) in media supplemented with 10 nM DHEA. The EHMT1/2 inhibitor, UNC0638 (Cayman, Cat. No. 10734) and SUV39H1 inhibitor, F5446 (Aobious, Cat. No. AOB17639) were used for treating the EnzR cells. Xenograft

(2) Druggable epigenetic suppression of interferon-induced chemokine expression linked to MYCN amplification in neuroblastomaJournal for ImmunoTherapy of CancerMay 20, 2021Johanna A Seier et al.before treatment to adhere at 60%–70% confluency. Either EHMT inhibitor UNC-0638 (Cayman Chemical, #10734) or BIX-01294 (AdipoGen, #AG-CR1-0051) were added to the culture media at concentrations of 1 µM–5 µM.

(3) Gain-of-Function Genetic Alterations of G9a Drive OncogenesisCancer DiscoveryJuly 1, 2020Shinichiro Kato et al.with 1% penicillin/streptomycin/L-glutamine and 10% FBS. UNC0638 was purchased from Cayman Chemical (#10734) and reconstituted with DMSO. UNC0642 was provided from Dr. Jian Jin for in vivo experiments. Bafilomycin A1

(4) Transcriptional repressor REST drives lineage stage–specific chromatin compaction at Ptch1 and increases AKT activation in a mouse model of medulloblastomaScience SignalingJanuary 24, 2019Tara H. W. Dobson et al.inhibitor MS275 (Cayman Chemicals, catalog # 13284) and G9a inhibitor UNC0638 (Cayman Chemicals, catalog # 10734), either alone or in combination for the time period indicated in the figures. After labeling with 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium

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UNC0638 from Cayman Chemical

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Cayman Chemical

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UNC0638 from Cayman Chemical

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