Wnt-C59 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemWnt-C59
CompanyTocris Bioscience, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog Number5148/10
Quantity10 mg (also 50 mg)
Purity0.99
Molecular Weight379.45
Molecule Name4-(2-Methyl-4-pyridinyl)-N-[4-(3-pyridinyl)phenyl]benzeneacetamide
FormulaC₂₅H₂₁N₃O
Brand/TrademarkTocris, a Bio-Techne Brand
StorageStore at -20°C

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Optimized synthesis and pharmacological evaluation of HCN channel inhibitor EC18Archiv der PharmazieJune 1, 2023Patberg M, Oniani T, Disse P, Peischard S, Vinnenberg L, Zobeiri M, Romanelli MN, Epping L, Wiendl H, Meuth SG, et al.

(2) A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticidesNature communicationsMay 16, 2023Paul KC, Krolewski RC, Lucumi Moreno E, Blank J, Holton KM, Ahfeldt T, Furlong M, Yu Y, Cockburn M, Thompson LK, et al.

(3) Engineered cardiac tissue model of restrictive cardiomyopathy for drug discoveryCell reports. MedicineMarch 21, 2023Wang BZ, Nash TR, Zhang X, Rao J, Abriola L, Kim Y, Zakharov S, Kim M, Luo LJ, Morsink M, et al.

(4) IGF-1 boosts mitochondrial function by a Ca(2+) uptake-dependent mechanism in cultured human and rat cardiomyocytesFrontiers in physiologyJanuary 1, 2023Sánchez-Aguilera P, López-Crisosto C, Norambuena-Soto I, Penannen C, Zhu J, Bomer N, Hoes MF, Van Der Meer P, Chiong M, Westenbrink BD, et al.

(5) Contribution of Trp63(CreERT2)-labeled cells to alveolar regeneration is independent of tuft cellseLifeSeptember 21, 2022Huang H, Fang Y, Jiang M, Zhang Y, Biermann J, Melms JC, Danielsson JA, Yang Y, Qiang L, Liu J, et al.

(6) Functional microvascularization of human myocardium in vitroCell Rep MethodsSeptember 19, 2022King O, Cruz-Moreira D, Sayed A, Kermani F, Kit-Anan W, Sunyovszki I, Wang BX, Downing B, Fourre J, Hachim D, et al.

(7) Time-regulated transcripts with the potential to modulate human pluripotent stem cell-derived cardiomyocyte differentiationStem cell research & therapySeptember 2, 2022Muñoz JJAM, Dariolli R, da Silva CM, Neri EA, Valadão IC, Turaça LT, Lima VM, de Carvalho MLP, Velho MR, Sobie EA, et al.replaced after 24 h (Day 3) with RPMI-1640 supplemented with B27 without insulin and 2 µM Wnt-C59 (5148/10, Tocris Bioscience) and incubated for 48 h. At day 5, media was replaced with RPMI-1640 supplemented

(8) SOX transcription factors direct TCF-independent WNT/β-catenin responsive transcription to govern cell fate in human pluripotent stem cellsCell reportsAugust 23, 2022Mukherjee S, Luedeke DM, McCoy L, Iwafuchi M, Zorn AM.

(9) STK25 inhibits PKA signaling by phosphorylating PRKAR1ACell reportsAugust 16, 2022Zhang X, Wang BZ, Kim M, Nash TR, Liu B, Rao J, Lock R, Tamargo M, Soni RK, Belov J, et al.

(10) Reengineering Ponatinib to Minimize Cardiovascular ToxicityCancer researchAugust 3, 2022Hnatiuk AP, Bruyneel AAN, Tailor D, Pandrala M, Dheeraj A, Li W, Serrano R, Feyen DAM, Vu MM, Amatya P, et al.

(11) Virus-induced inhibition of cardiac pacemaker channel HCN4 triggers bradycardia in human-induced stem cell systemCellular and molecular life sciences : CMLSJuly 21, 2022Peischard S, Möller M, Disse P, Ho HT, Verkerk AO, Strutz-Seebohm N, Budde T, Meuth SG, Schweizer PA, Morris S, et al.

(12) Paraxial mesoderm organoids model development of human somiteseLifeJanuary 28, 2022Budjan C, Liu S, Ranga A, Gayen S, Pourquié O, Hormoz S.

(13) Single-cell sequencing reveals lineage-specific dynamic genetic regulation of gene expression during human cardiomyocyte differentiationPLoS geneticsJanuary 1, 2022Elorbany R, Popp JM, Rhodes K, Strober BJ, Barr K, Qi G, Gilad Y, Battle A.

(14) Selenoprotein DIO2 Is a Regulator of Mitochondrial Function, Morphology and UPRmt in Human CardiomyocytesInternational journal of molecular sciencesNovember 2, 2021Bomer N, Pavez-Giani MG, Deiman FE, Linders AN, Hoes MF, Baierl CLJ, Oberdorf-Maass SU, de Boer RA, Silljé HHW, Berezikov E, et al.

(15) Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditionseLifeMay 14, 2021Findley AS, Monziani A, Richards AL, Rhodes K, Ward MC, Kalita CA, Alazizi A, Pazokitoroudi A, Sankararaman S, Wen X, et al.

(16) The thrombin receptor links brain derived neurotrophic factor to neuron cholesterol production, resiliency and repair after spinal cord injuryNeurobiology of diseaseMay 1, 2021Triplet EM, Kim HN, Yoon H, Radulovic M, Kleppe L, Simon WL, Choi CI, Walsh PJ, Dutton JR, Scarisbrick IA.

(17) A Comparative Assessment of Marker Expression Between Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells and the Developing Pig HeartStem cells and developmentApril 1, 2021Lauschke K, Volpini L, Liu Y, Vinggaard AM, Hall VJ.

(18) Isolation of human ESC-derived cardiac derivatives and embryonic heart cells for population and single-cell RNA-seq analysisSTAR protocolsMarch 19, 2021Santoro F, Chien KR, Sahara M.

(19) Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytesSTAR protocolsMarch 19, 2021Maas RGC, Lee S, Harakalova M, Snijders Blok CJB, Goodyer WR, Hjortnaes J, Doevendans PAFM, Van Laake LW, van der Velden J, Asselbergs FW, et al.

(20) Dynamic effects of genetic variation on gene expression revealed following hypoxic stress in cardiomyocyteseLifeFebruary 8, 2021Ward MC, Banovich NE, Sarkar A, Stephens M, Gilad Y.

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Wnt-C59

Wnt-C59 from Tocris Bioscience, a Bio-Techne Brand

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Tocris Bioscience, a Bio-Techne Brand

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Wnt-C59 from Tocris Bioscience, a Bio-Techne Brand

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