Wnt-C59 from Biorbyt

Product Specs
ItemWnt-C59
CompanyBiorbyt
Price Pricing Info Supplier Page
Catalog Numberorb181132
Quantity10 mM * 1 mL in DMSO, 100 mg, 250 mg, 1000 mg
Molecular Weight379.45
FormulaC25H21N3O

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Biorbyt

7, Signet Court

Swann Road

Cambridge, Cambridgeshire CB5 8LA

United Kingdom

Phone: +44(0)1223 815 212
+44(0)1223 280 240 (fax)
+44(0)1223 280 240

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Website: https://www.biorbyt.com/

(1) Spatially resolved multiomics of human cardiac nichesNatureJuly 27, 2023Kazumasa Kanemaru, James Cranley, Daniele Muraro, Antonio M. A. Miranda, Siew Yen Ho, Anna Wilbrey-Clark, Jan Patrick Pett, Krzysztof Polanski, Laura Richardson, Monika Litvinukova, et al.cell culture medium was replaced with RPMI/ B27, minus insulin. For the next 2 days, 2 μM Wnt-C59 (Biorbyt, orb181132) was added in RPMI/B27, minus insulin. Cells were then cultured in RPMI/B27, minus insulin, with media

(2) Pathogenesis of Cardiomyopathy Caused by Variants in ALPK3, an Essential Pseudokinase in the Cardiomyocyte Nucleus and SarcomereCirculationNovember 29, 2022Agarwal R, Wakimoto H, Paulo JA, Zhang Q, Reichart D, Toepfer C, Sharma A, Tai AC, Lun M, Gorham J, et al.with B27 minus insulin for 2 days (days 1 to 2). Cultures were then treated with 2 μM Wnt-C59 (Biorbyt orb181132) in RPMI supplemented with B27 minus insulin for 2 days (days 3 to 5). Cells were maintained in RPMI

(3) Genome-wide association analyses identify novel Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibilityNature GeneticsMarch 1, 2022Julien Barc et al.(GenDEPOT, A0100), 200 μg/ml L-ascorbic acid 2-phosphate (Wako, 321-44823) and 0.5 μM Wnt-C59 (Biorbyt, orb181132). Medium was then changed on day 4 and then every other day with RBAI consisting of RPMI supplemented

(4) Lymphoangiocrine signals promote cardiac growth and repairNatureDecember 1, 2020Liu X, De la Cruz E, Gu X, Balint L, Oxendine-Burns M, Terrones T, Ma W, Kuo HH, Lantz C, Bansal T, et al.is changed to CDM3. On day 2, medium is changed to CDM3 supplemented with 2 μM of Wnt-C59 (Biorbyt, orb181132). Medium is then changed every other day for CDM3 starting on day 4. Contracting cells are noted from

(5) Cardiac Ischemic Preconditioning Promotes MG53 Secretion Through H ₂ O ₂ -Activated Protein Kinase C-δ SignalingCirculationSeptember 15, 2020Dan Shan et al.hours later, the medium was changed to basal medium supplied with 2 μmol/LWnt-C59 (Biorbyt, catalog no. orb181132) for another 48 hours. The cells were then maintained in basal medium, changing to fresh media every 48

(6) Negligible-Cost and Weekend-Free Chemically Defined Human iPSC CultureStem Cell ReportsFebruary 1, 2020Hui-Hsuan Kuo et al.and on day 2 the medium was changed to CDM3 supplemented with 2 μM Wnt inhibitor Wnt-C59 (Biorbyt, orb181132). The medium was then changed on day 4 and then every other day with CDM3. Contracting cells were noted

(7) Use of human induced pluripotent stem cell-derived cardiomyocytes to assess drug cardiotoxicityNature protocolsDecember 1, 2018Sharma A, McKeithan WL, Serrano R, Kitani T, Burridge PW, Del Álamo JC, Mercola M, Wu JC.no. OsrHSA-100) CHIR99021 (Thermo Fisher Scientific, cat. no. 508306) Wnt-C59 (Biorbyt, cat. no. orb181132) Rho kinase (ROCK) inhibitor (Tocris, cat. no. 1254) 0.5 M EDTA (Thermo Fisher Scientific, cat.

(8) Differentiation and Contractile Analysis of GFP-Sarcomere Reporter hiPSC-CardiomyocytesCurrent protocols in human geneticsJanuary 24, 2018Sharma A, Toepfer CN, Schmid M, Garfinkel AC, Seidman CE.no. 17504-044) CHIR99021 (Thermo Fisher Scientific, cat. no. 508306) Wnt-C59 (Biorbyt, cat. no. orb181132) 6-well tissue culture-treated plates Standard cell culture laminar flow hood mTeSR1 medium (StemCell Technologies

(9) Chemically Defined Culture and Cardiomyocyte Differentiation of Human Pluripotent Stem CellsCurrent protocols in human geneticsOctober 6, 2015Burridge PW, Holmström A, Wu JC.cat. no. orb154612), 600 μL aliquots at 10 mM in DMSO, store at −20 °C Wnt-C59 (Biorbyt, cat. no. orb181132), 200 μL aliquots at 10 mM in DMSO, store at −20 °C L-lactic acid (Wako Chemicals USA, cat. no. 129-02666),

(10) Developmental changes in integrin beta-subunits in rat cerebral cortexNeuroscience lettersOctober 3, 1997Cousin B, Leloup C, Pénicaud L, Price J.

(11) Strain-related differences in airway smooth muscle and airway responsiveness in the ratThe American review of respiratory diseaseOctober 1, 1991D H Eidelman, G U DiMaria, S Bellofiore, N S Wang, R D Guttmann, J G Martin

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Wnt-C59

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Wnt-C59 from Biorbyt

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