Pam3Cys-Ser-(Lys)4, TLR1/TLR2 agonist from Abcam

Product Specs
ItemPam3Cys-Ser-(Lys)4, TLR1/TLR2 agonist
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab142085
Quantity100 UG

Sequence

CSKKKK

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Bacterial lipoprotein plays an important role in the macrophage autophagy and apoptosis induced by Salmonella typhimurium and Staphylococcus aureusOpen Life SciencesSeptember 30, 2023Shanshan Jiang, Jinyao He, Lijie Zhang, Qiaojiajie Zhao, Shuqi Zhaomacrophages by BLP. 2 Materials and methods 2.1 Reagents and antibodies BLP (Pam3Cys-Ser-Lys4, ab142085) was purchased from Abcam (Cambridge, UK). Gram-negative S. typhimurium (CMCC50097) and Gram-positive

(2) Sperm activate TLR2/TLR1 heterodimerization to induce a weak proinflammatory response in the bovine uterusFrontiers in ImmunologyApril 27, 2023Alireza Mansouri, Mohamed Samy Yousef, Rasoul Kowsar, Nonoka Usui, Ihshan Akthar, Akio MiyamotoTLR2 agonists. Bovine endometrial epithelial cells (BEECs) were stimulated with PAM3 (TLR2/1 agonist, ab142085, Abcam) and PAM2 (TLR2/6 agonist, InvivoGen, USA) at 100 ng/mL concentration for 1h. The concentration

(3) IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemiaEMBO molecular medicineJanuary 11, 2023Liu X, Sato N, Yabushita T, Li J, Jia Y, Tamura M, Asada S, Fujino T, Fukushima T, Yonezawa T, et al.doses of MPA (1–10 μM) were added together with TLR ligands (TLR1/2 ligand: 100 ng/ml of Pam3CSK4 [#ab142085, Abcam]), TLR4 ligand: 100 ng/ml Lipid A (E. coli; #24005‐s, PEPTIDE INSTITUTE); TLR5 ligand: 10 ng/ml

(4) Toll-like Receptor 2 is Involved in Calcium Influx and Acrosome Reaction to Facilitate Sperm Penetration to Oocytes During in vitro Fertilization in CattleFrontiers in Cell and Developmental BiologyFebruary 24, 2022Dongxue Ma, Mohamed Ali Marey, Masayuki Shimada, Akio Miyamoto(CU-CPT22, Calbiochem) (Cheng et al., 2012; Grabowski, et al., 2020) or Pam3Cys, a synthetic TLR2 ligand (ab142085, Abcam) (Reitermann et al., 1989) was used to specifically and selectively block or activate the sperm

(5) Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathwayBone & joint researchAugust 1, 2021Liu ZM, Lu CC, Shen PC, Chou SH, Shih CL, Chen JC, Tien YC.kit was obtained from Biovision (USA); TLR2-specific agonist Pam3CSK4 was obtained from Abcam (Pam; ab142085); TAK-242, a specific inhibitor of Toll-like receptor 4 signalling, was obtained from Merck (Germany);

(6) Peptidoglycan Switches Off the TLR2-Mediated Sperm Recognition and Triggers Sperm Localization in the Bovine EndometriumFrontiers in ImmunologyFebruary 11, 2021Ibrahim Fouad Elesh et al.pre-exposed to pam3Cys-Ser-(Lys)4, a synthetic analog of the triacylated N-terminal part of bacterial PGN (ab142085, Abcam) (10 pg ml−1), for 24 h followed by co-culture with sperm for 6 h. For blocking by the TLR2 antagonist

(7) TLR2/4 signaling pathway mediates sperm-induced inflammation in bovine endometrial epithelial cells in vitroPLOS ONEApril 17, 2019Mohamed Aboul Ezz et al.for 0, 1, 3, or 6 h (the same time window used for spermBEECs co-culture). Pam3Cys-Ser-(Lys)4 (Pam; ab142085, Abcam) was used (at 10, 100, and 1000 ng/ml) as TLR2 agonist [21], while or LPS from E. coli O55:B5

(8) TLR9 activation via microglial glucocorticoid receptors contributes to degeneration of midbrain dopamine neuronsNature CommunicationsDecember 1, 2018Layal Maatouk et al.St. Quentin Fallavier, France), 1 μg of TLR2 agonist (Pam3Cys-Ser- (Lys) 4 Trihydrochloride; Abcam, ab142085), 1 μg of TLR7 agonist, Imiquimod (Enzo Life Sciences, ALX-420-039-M100), 0.96 μg (1 μM) of TLR9 agonist

(9) MicroRNA 27a-3p Regulates Antimicrobial Responses of Murine Macrophages Infected by Mycobacterium avium subspecies paratuberculosis by Targeting Interleukin-10 and TGF-β-Activated Protein Kinase 1 Binding Protein 2Frontiers in immunologyJanuary 1, 2017Hussain T, Zhao D, Shah SZA, Wang J, Yue R, Liao Y, Sabir N, Yang L, Zhou X.mimic, inhibitor control, and inhibitor were purchased from Shanghai GenePharma. Pam3Cys-Ser-(Lys)4 (ab142085), a TLR1/TLR2 agonist, was purchased from Abcam Biotechnology; lipofectamine 2000 from Invitrogen Thermo

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Pam3Cys-Ser-(Lys)4, TLR1/TLR2 agonist from Abcam

Description

Sequence

Abcam

Citations (9)

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Pam3Cys-Ser-(Lys)4, TLR1/TLR2 agonist from Abcam

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