Description
An antiviral agent and active metabolite of brincidofovir; inhibits CMV DNA synthesis in a cell-free assay; inhibits replication of two CMV strains in plaque formation assays (IC50s = 0.1 and 0.07 µg/ml for Davis and AD-169 strains, respectively); decreases mortality in mouse models of cowpox or vaccinia virus infections at 15 mg/kg