Mdivi-1 from MedChemExpress

Product Specs
ItemMdivi-1
CompanyMedChemExpress
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberHY-15886
TypeChemical
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Quantity5 mg
Purity99.73%

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(1) Fucoxanthin ameliorates traumatic brain injury by suppressing the blood-brain barrier disruptioniScienceNovember 17, 2023Zhang L, Hu Z, Bai W, Peng Y, Lin Y, Cong Z.peptides, and recombinant proteins" ,, Fucoxanthin,Sigma-Aldrich,Cat#F6932 Mdivi-1,MedChemExpress,Cat#HY-15886 ,, Critical commercial assays,Critical commercial assays,Critical commercial assays ,, TB staining

(2) The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cellsmBioNovember 1, 2023Jing Cheng, Yutong Wang, Lizheng Yin, Wenzhang Liang, Jing Zhang, Cuiqing Ma, Yu Zhang, Bo Liu, Jiachao Wang, Weiting Zhao, et al.Biosciences,YKO-RP003-hTAX1BP1[gRNA1] Chemical reagents,, Bafilomycin A1,Cayman,11038 Mdivi-1,MedChemExpress,HY-15886 Lipofectamine 2000,Invitrogen,11668019 Carbonyl cyanide 3-chlorophenylhydrazo,Solarbio,C6700 List

(3) Isoquercitrin from Apocynum venetum L. Exerts Antiaging Effects on Yeasts via Stress Resistance Improvement and Mitophagy Induction through the Sch9/Rim15/Msn Signaling PathwayAntioxidants (Basel)October 31, 2023Yanan Liu, Le Shen, Akira Matsuura, Lan Xiang, Jianhua Qi(Beyotime Biotechnology, Shanghai, China); CSK3-IN-3 (HY-153089, MedChemExpress, Shanghai, China); Mdivi-1 (HY-15886, MedChemExpress, Shanghai, China); dimethyl sulfoxide (DMSO) (Sigma, Saint Louis, MO, USA); Hoechst

(4) SARS-CoV-2 Nsp8 induces mitophagy by damaging mitochondriaVirologica SinicaAugust 1, 2023Zong S, Wu Y, Li W, You Q, Peng Q, Wang C, Wan P, Bai T, Ma Y, Sun B, et al.treatment Chloroquine (CQ, Cat#HY-17589A), CCCP (Cat#HY-100941); bafilomycin A1 (Baf A1, Cat#HY-100558), Mdivi-1 (Cat#HY-15886), and N-Acetyl-l-cysteine (NAC, Cat#HY-B0215) were purchased from MedChemExpress (Shanghai, China).

(5) The physiological metabolite α-ketoglutarate ameliorates osteoarthritis by regulating mitophagy and oxidative stressRedox biologyJune 1, 2023Liu L, Zhang W, Liu T, Tan Y, Chen C, Zhao J, Geng H, Ma C.and fetal bovine serums (FBS) were obtained from Gibco™ (California, USA). Mdivi-1 (CAS. 338967-87-6, HY-15886) and Bafilomycin A1 (CAS. 88899-55-2, HY-100558) were purchased from MedChemExpress™ (Monmouth Junction,

(6) Berberine Rescues D-Ribose-Induced Alzheimer's Pathology via Promoting MitophagyInternational journal of molecular sciencesMarch 20, 2023Wang C, Zou Q, Pu Y, Cai Z, Tang Y.Pharmaceutical Co., Ltd., Sichuan, China), D-ribose (V900389, Sigma-Aldrich, St. Louis, MO, USA), Mdivi-1 (HY-15886, MedChemExpress, Monmouth Junction, NJ, USA), 5-Azacytidine (HY-10586, MedChemExpress, Monmouth Junction,

(7) Continued P2X7 activation leads to mitochondrial fission and compromising microglial phagocytosis after subarachnoid haemorrhageJournal of NeurochemistryDecember 1, 2022Tao Tao, Xiangxin Chen, Yan Zhou, Qiang Zheng, Sen Gao, Jinwei Wang, Pengfei Ding, Xiaojian Li, Zheng Peng, Yue Lu, et al.same concentration (Coddou et al., 2011). Both JNJ‐47965567 (100 nM), Mdivi‐1 (10 μM, MedChemExpress #HY‐15886, Shanghai) and FK506 (1 μM, MedChemExpress #HY‐13756, Shanghai) were added to the culture medium 24

(8) Mitochondria dysfunction in Charcot Marie Tooth 2B Peripheral Sensory NeuropathyCommunications BiologyDecember 1, 2022Yingli Gu et al.D22421) were purchased from Invitrogen (Carlsbad, CA). Mdivi-1 was purchased from MedChemExpress (Cat# HY-15886). CID11067700 was from Sigma (cat# SML0545). Both Mdivi-1 and CID11067700 were dissolved in dimethyl

(9) Morphine-induced microglial immunosuppression via activation of insufficient mitophagy regulated by NLRX1Journal of neuroinflammationApril 12, 2022Peng J, Pan J, Wang H, Mo J, Lan L, Peng Y.was approved by Guangdong Medical Products Administration. CCCP (10 μM, HY-100941), Mdivi-1 (20 μM, HY-15886) and Bafilomycin A1 (20 nM, HY-100558) were purchased from MedChemExpress. Torin1 (250 μM, SC0245) was

(10) The intestinal microbial metabolite nicotinamide n-oxide prevents herpes simplex encephalitis via activating mitophagy in microgliaGut microbesJanuary 1, 2022Li F, Wang Y, Song X, Wang Z, Jia J, Qing S, Huang L, Wang Y, Wang S, Ren Z, et al.University, China). Acyclovir (ACV) was purchased from Sigma-Aldrich (St. Louis, MO, USA). Mdivi-1 (HY-15886) was purchased from MedChemExpress (New Jersey, USA). mitoKeima was purchased from mKeima-RedMito-7

(11) Drp1-Mediated Mitochondrial Metabolic Dysfunction Inhibits the Tumor Growth of Pituitary AdenomasOxidative medicine and cellular longevityJanuary 1, 2022Fan K, Ding X, Zang Z, Zhang Y, Tang X, Pei X, Chen Q, Yin H, Zheng X, Chen Y, et al.and puromycin (Beyotime, ST551). The following reagents were purchased from MedChemExpress: Mdivi-1 (HY-15886), Mito-TEMPO (HY-112879), cyclosporin A (CsA; HY-B0579), Compound C (CC; HY-13418A), and 3-methyladenine

(12) SARS-CoV-2 ORF10 suppresses the antiviral innate immune response by degrading MAVS through mitophagyCellular & molecular immunologyJanuary 1, 2022Li X, Hou P, Ma W, Wang X, Wang H, Yu Z, Chang H, Wang T, Jin S, Wang X, et al.Dimethyl sulfoxide (DMSO),Sigma-Aldrich,472301 MG132,MedChemExpress,HY-13259 Bafilomycin A1,MedChemExpress,HY-100558 Mdivi-1,MedChemExpress,HY-15886 Poly(I:C) (LMW),InvivoGen,tlrl-picw Chloroquine diphosphate salt,Sigma-Aldrich,C6628 Attractene Transfection Reagent

(13) The mitochondrial fission factor FIS1 promotes stemness of human lung cancer stem cells via mitophagyFEBS open bioJuly 1, 2021Liu D, Sun Z, Ye T, Li J, Zeng B, Zhao Q, Wang J, Xing HR.Medical University. Reagents for inhibiting and inducing mitophagy The mitophagy inhibitor Mdivi‐1 (HY‐15886) and the inducer CCCP (HY‐100941) were purchased from MedChemExpress (Monmouth Junction, NJ, USA). Cell culture

(14) ERK/Drp1-dependent mitochondrial fission contributes to HMGB1-induced autophagy in pulmonary arterial hypertensionCell proliferationJune 1, 2021Feng W, Wang J, Yan X, Zhang Q, Chai L, Wang Q, Shi W, Chen Y, Liu J, Qu Z, et al.injection 8 , 9 ; MCT+Mitochondrial division inhibitor (Mdivi‐1) group: received Mdivi‐1 (50 mg/kg, HY‐15886, MedChemExpress, NJ, USA) by twice weekly ip injection 12 ; MCT+CQ group: received CQ (50 mg/kg, Aladdin,

(15) Triptolide Induces Leydig Cell Apoptosis by Disrupting Mitochondrial Dynamics in RatsFrontiers in pharmacologyJanuary 1, 2021Lv L, Chang Y, Li Y, Chen H, Yao J, Xie Y, Liang X, Yang X, Zhang M, Liu G.Agents Triptolide (TP; cat. no. HY-32735) and mitochondrial division inhibitor 1 (Mdivi-1; cat. no. HY-15886) were purchased from MedChemExpress. Brieﬂy, 1 mg TP was dissolved in 2.7747 ml dimethyl sulfoxide (DMSO)

(16) SARS-CoV-2 Causes Mitochondrial Dysfunction and Mitophagy ImpairmentFrontiers in microbiologyJanuary 1, 2021Shang C, Liu Z, Zhu Y, Lu J, Ge C, Zhang C, Li N, Jin N, Li Y, Tian M, et al.Research Institute. In our experiments, cells were infected with SARS-CoV-2 at a MOI of 0.008. Mdivi-1 (HY-15886) and cyclosporin A (HY-B0579) were purchased from MedChemExpress (New Jersey, United States). Antibodies The

(17) PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer CellsFrontiers in pharmacologyJanuary 1, 2019Zhao C, He R, Shen M, Zhu F, Wang M, Liu Y, Chen H, Li X, Qin R.necrosulfonamide (No. HY-100573, purity: 99.23%), ferrostatin-1 (No. HY-100579, purity: 99.72%), and Mdivi-1 (HY-15886, purity: 98.75%) were obtained from MedChemExpress (Monmouth, NJ, USA). Z-VAD-FMK was purchased from

(18) [Combination chemotherapy of advanced bladder cancer]Hinyokika kiyo. Acta urologica JaponicaDecember 1, 1986Kiyohara H.

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Mdivi-1 from MedChemExpress

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Mdivi-1 from MedChemExpress

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