Ferrostatin-1 from MedChemExpress

Product Specs
ItemFerrostatin-1
CompanyMedChemExpress
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberHY-100579
TypeChemical
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Quantity5 mg
Purity99.96%

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(1) Gongying-Jiedu-Xiji recipe promotes the healing of venous ulcers by inhibiting ferroptosis via the CoQ-FSP1 axisFront PharmacolDecember 15, 2023Yongpan Lu, Dejie Zhao, Ming Liu, Guoqi Cao, Chunyan Liu, Siyuan Yin, Ru Song, Jiaxu Ma, Rui Sun, Zhenjie Wu, et al.protein 1 (iFSP1) (Cat. No: HY-136057) was purchased from MedChemExpress. Ferrostatin-1 (Cat. No.: HY-100579) was purchased from MedChemExpress. 2.2 Preparation of DDL and high-performance liquid chromatography

(2) ALOX5 deficiency contributes to bladder cancer progression by mediating ferroptosis escapeCell Death DisDecember 7, 2023Tianyao Liu, Xinyan Xu, Jiazheng Li, Ming Bai, Wenjie Zhu, Yanqing Liu, Siyang Liu, Zihan Zhao, Tianhang Li, Ning Jiang, et al.autophagy inhibitor, A8353) were purchased from APExBIO (USA). Ferrostatin-1 (ferroptosis inhibitor, HY-100579) and Deferoxamine (DFO, ferroptosis inhibitor, HY-B1625) were obtained from MedChemExpress (MCE, USA).

(3) Ferulic Acid Activates SIRT1-Mediated Ferroptosis Signaling Pathway to Improve Cognition Dysfunction in Wilson's DiseaseNeuropsychiatr Dis TreatDecember 5, 2023Xie Wang, Nan Shao, Xiaoyan Zhang, Hong Chen, Ze Chang, Daojun Xie, Juan ZhangSC-74504); GAPDH antibody (Immunoway, TX, USA; Cat. YN5585); ferrostatin-1 (MedChemExpress, NJ, USA; Cat. HY-100579); HRP-conjugated goat anti-rabbit IgG (Abbkine, Wuhan, China; Cat. A21021); hematoxylin (HE) staining

(4) Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6PCell researchDecember 1, 2023Ai YL, Wang WJ, Liu FJ, Fang W, Chen HZ, Wu LZ, Hong X, Zhu Y, Zhang CX, Liu LY, et al.3× FLAG peptide (Cat# HY-P0319A), Y-27632 (Cat# HY-10583), CQ (Cat# HY-17589A), Ferrostatin-1 (Cat# HY-100579), MG132 (Cat# HY-13259) and metformin (Cat# HY-17471A) were purchased from MedChemExpress. Liproxstatin-1

(5) Molecular mechanism of interleukin-17A regulating airway epithelial cell ferroptosis based on allergic asthma airway inflammationRedox BiologyDecember 1, 2023Jingjing Song, Hui Zhang, Yu Tong, Yufei Wang, Qiangwei Xiang, Huan Dai, Cuiye Weng, Lei Wang, Junwen Fan, Yilong Shuai, et al.before erastin (1 μM/mL, Cat #: HY-15763, MedChemExpress, USA), ferrostain-1 (Ferr-1, 0.1 μM/mL, Cat #: HY-100579, MedChemExpress, USA), N-Acetyl cysteine (NAC, 1 mM/mL, Cat #: HY-B0215, MedChemExpress, USA), and IL-17A antagonist 1

(6) Erastin induces ferroptosis in cervical cancer cells via Nrf2/HO-1 signaling pathwayInternational Journal of Immunopathology and PharmacologyDecember 1, 2023Xiaoning Wei, Qiaoqiao Huang, Jinbing Huang, Li Yu, Junying Chena humidified environment with 5% CO2 at 37°C. Ferrostatin-1 (1 mg) (MedChemExpress, China, cat no. HY-100579) was dissolved in 0.3812 mL of DMSO (Sigma-Aldrich, USA, cat no. 67685), with the assistance of sonication,

(7) Fucoidan Ameliorates Ferroptosis in Ischemia-reperfusion-induced Liver Injury through Nrf2/HO-1/GPX4 ActivationJournal of Clinical and Translational HepatologyNovember 28, 2023Jing-Jing Li, Wei-Qi Dai, Wen-Hui Mo, Wen-Qiang Xu, Yue-Yue Li, Chuan-Yong Guo, Xuan-Fu Xuprepared as a mother liquor at a concentration of 20 mg/mL and stored at 4°C refrigerator. Fer-1 (Cat. No. HY-100579), erastin (Cat. No. HY-15763) and MG-132 (Cat. No. HY-13259) were obtained from MedChemExpress (Monmouth

(8) Licochalcone A Induces Ferroptosis in Hepatocellular Carcinoma via Reactive Oxygen Species Activated by the SLC7A11/GPX4 PathwayIntegrative Cancer TherapiesNovember 15, 2023Jin-Xin Zhang, Yan Xiao, Yi-Quan Li, Yi-Long Zhu, Ya-Ru Li, Ren-Shuang Zhao, Ning-Yi Jin, Jin-Bo Fang, Xiao Li, Ji-Cheng Hancontaining 10% fetal bovine serum. Lico A (Cat# HY-N0372) and Ferrostatin-1 (ferroptosis inhibitor, Cat# HY-100579) were purchased from MedChemExpress. BALB/c nude mice (5 weeks old) were purchased from Beijing Viton

(9) Inhibition of LSD1 induces ferroptosis through the ATF4-xCT pathway and shows enhanced anti-tumor effects with ferroptosis inducers in NSCLCCell Death & DiseaseNovember 3, 2023Linna Du, Han Yang, Yufei Ren, Yanli Ding, Yichao Xu, Xiaolin Zi, Hongmin Liu, Pengxing Heantibodies ORY-1001 (ORY; HY-12782T), Erastin (ERA; HY-15763), (1S,3R)-RSL3 (RSL; HY-100218A), Ferrostatin-1 (Fer-1; HY-100579), Z-VAD-FMK (ZVAD; HY-16658B), Bafilomycin A1 (BA1; HY-100558), and Necrostatin-1 (Nec1; HY-15760) were

(10) Tobacco toxins induce osteoporosis through ferroptosisRedox BiologyNovember 1, 2023Zheng Jing, Yuzhou Li, He Zhang, Tao Chen, Jinrui Yu, Xinxin Xu, Yulong Zou, Xu Wang, Kai Xiang, Xuerui Gong, et al.osteoporosis in smokers. 4 Materials and methods 4.1 Materials and reagents Ferrostatin-1 (Fer-1, HY-100579), Necrostatin-1(Nec-1, HY-15760), Z-VAD-FMK (HY-16658B), 3-methyladenine (3-MA; HY-19312), Mitoquinone mesylate

(11) Sirtuin4 alleviates severe acute pancreatitis by regulating HIF-1α/HO-1 mediated ferroptosisCell Death & DiseaseOctober 21, 2023Yanna Liu, Huning Cui, Chaopeng Mei, Mengwei Cui, Qianqian He, Qiaofang Wang, Dejian Li, Yaodong Song, Jiye Li, Sanyang Chen, et al.purchased from Chengdu Fuji Biotechnology Co., Ltd. (Chengdu, China). The ferroptosis inhibitor Fer-1 (HY-100579) and HIF-1α inhibitor PX478 (HY-10231) were both purchased from MedChemExpress Corporation (Shanghai,

(12) Use of Deep‐Learning Assisted Assessment of Cardiac Parameters in Zebrafish to Discover Cyanidin Chloride as a Novel Keap1 Inhibitor Against Doxorubicin‐Induced CardiotoxicityAdvanced ScienceOctober 1, 2023Changtong Liu, Yingchao Wang, Yixin Zeng, Zirong Kang, Hong Zhao, Kun Qi, Hongzhi Wu, Lu Zhao, Yi WangDox treatment from 30hpf to 100hpf. For the test with different cell death inhibitors, Fer‐1 (1 µm; HY‐100579, MedChemExpress, USA), 3‐MA (250 µM; HY‐19312, MedChemExpress, USA), Emricasan (50 µM; HY‐10396, MedChemExpress,

(13) GAS1 Promotes Ferroptosis of Liver Cells in Acetaminophen-Induced Acute Liver FailureInternational Journal of Medical SciencesSeptember 25, 2023Jinqiu Tao, Cailin Xue, Xiaodong Wang, Huihui Chen, Qiaoyu Liu, Chunping Jiang, Wenjie Zhangused. It was maintained at 37°C and 5% CO2. Reagents and antibodies APAP (HY-66005), ferrostatin-1 (HY-100579), RSL (HY-100218A) and erastin (HY-15763) were purchased from MedChemExpress (New Jersey, USA). Anti-α-tubulin

(14) Knockdown of ANXA10 induces ferroptosis by inhibiting autophagy-mediated TFRC degradation in colorectal cancerCell Death & DiseaseSeptember 4, 2023Xinyuan Wang, Yujie Zhou, Lijun Ning, Jinnan Chen, Huimin Chen, Xiaobo Li(A-21207) conjugated secondary antibodies were purchased from Invitrogen (CA, USA). Ferrostatin-1 (HY-100579), Deferoxamine mesylate (HY-B0988), Rapamycin (HY-10219), and Chloroquine (HY-17589A) were purchased

(15) Inhibition of inflammatory factor TNF-α by ferrostatin-1 in microglia regulates necroptosis of oligodendrocyte precursor cellsNeuroReportAugust 24, 2023Zhi Chai, Teng Ma, Yunhong Li, Qiuyuan Chen, Yali Kang, Jinping Sun, Tao Peng, Nina Wang, Chengjun Yu, Lijuan Wang, et al.from Guangzhou Cellcook Biotech Co., Ltd., Guangzhou International Biological Island Fer-1 (cat. no. HY-100579) and Nec-1 (cat. no. HY-15706) were purchased from MedChemExpress, Pudong New Area, Shanghai. ROS (cat.

(16) ANO1‐Mediated Inhibition of Cancer Ferroptosis Confers Immunotherapeutic Resistance through Recruiting Cancer‐Associated FibroblastsAdvanced ScienceAugust 1, 2023Fangli Jiang, Keren Jia, Yang Chen, Congcong Ji, Xiaoyi Chong, Zhongwu Li, Feilong Zhao, Yuezong Bai, Sai Ge, Jing Gao, et al.were from ZSGB‐BIO. For reagents, CAI (HY‐100611)/BBR (HY‐B1135)/erastin (HY‐15763)/ferrostatin‐1 (HY‐100579)/liproxstatin‐1 (HY‐12726)/dactolisib (BEZ235, HY‐50673)/talabostat mesylate (HY‐13233A) were from MedChemExpress

(17) Circ-STC2 promotes the ferroptosis of nucleus pulposus cells via targeting miR-486-3p/TFR2 axisJournal of Orthopaedic Surgery and ResearchJuly 21, 2023Liangping Xiong, Xiaoyan Li, Xi Hua, Zhonglai Qianwere treated with 10 μM simvastatin (SIM; 1002347-74-1, MedChemExpress), 5 μM ferrostatin-1 (Fer-1; HY‐100579, MedChemExpress), 20 μg/ml iron-saturated holo-transferrin (HTF; T1283, Sigma) and 4 μM Erastin (571203-78-6,

(18) Vitronectin Destroyed Intestinal Epithelial Cell Differentiation through Activation of PDE4-Mediated Ferroptosis in Inflammatory Bowel DiseaseMediators of InflammationJuly 19, 2023Wenxu Pan, Li Xiang, Xinhua Liang, Wenjun Du, Junhong Zhao, Song Zhang, Xuan Zhou, Lanlan Geng, Sitang Gong, Wanfu XuMethods 2.1. Chemical Reagents and Antibodies VTN (459 a.a, HEK293, His), RSL3 (HY-100218A), Ferrostatin-1 (HY-100579), DIP (HY-B0312), and Rofi (HY-15455S2) were purchased from MedChemExpress (Shanghai, China). Antibodies

(19) Ferrostatin-1 alleviates the damage of C2C12 myoblast and mouse pelvic floor muscle induced by mechanical traumaCell death discoveryJuly 7, 2023He Y, Huang G, Hong S, Zuo X, Zhao Z, Hong L.were provided. Chemicals and reagents Ferrostatin-1 (Fer-1) was purchased from MedChemExpress (MCE, HY-100579, Monmouth Junction, USA) and dissolved in DMSO (Sigma-Aldrich, D4540) and stored at −20 °C. Other reagent

(20) Attenuation of Sepsis-Induced Acute Kidney Injury by Exogenous H2S via Inhibition of FerroptosisMoleculesJune 14, 2023Li Zhang, Jin Rao, Xuwen Liu, Xuefu Wang, Changnan Wang, Shangxi Fu, Jian Xiaofrom Beyotime Biotechnology (Shanghai, China). Ferrostatin-1 (Fer-1) and Mito-TEMPO detection kits (HY-100579 and HY-112879, respectively) were obtained from Medchemexpress (Shanghai, China). 4.2. Animals and

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Ferrostatin-1 from MedChemExpress

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Ferrostatin-1 from MedChemExpress

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