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Protein Biochemistry
Chemicals and Reagents
Stattic
Stattic from MedChemExpress
Be the first to write a review!
Citations:
(16)
Supplier Page
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MedChemExpress for
Stattic
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Company Info
Citations
Reviews
Product Specs
Item
Stattic
Company
MedChemExpress
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
HY-13818
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
98.92%
Type
Chemical
Molecular Weight
211.19
Formula
C₈H₅NO₄S
Research Area
Inflammation/Immunology; Cancer
Add to Compare List
MedChemExpress
1 Deer Park Dr, Suite Q
Monmouth Junction
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (16)
(1)
KDF1 Promoted Proliferation, Migration and Invasion of Lung Adenocarcinoma Cells through Activating STAT3 and AKT Pathway
Biomedicines
December 1, 2023
Yi-Qing Guo, Mei-Fu Gan, Jia-Qian Bao, Han-Xi Zhou, Jing Yang, Chuan-Jing Dai, Jing-Min Zheng
used
LY294002
(Cat.No
HY-10108
,
MedChemExpress
LLC, Monmouth Junction, NJ, USA) and
Stattic
(Cat.No
HY-13818
,
MedChemExpress
LLC, Monmouth Junction, NJ, USA) to
inhibit
the activation of the
AKT
and
STAT3
pathway,
(2)
Aryl hydrocarbon receptor regulates IL-22 receptor expression on thymic epithelial cell and accelerates thymus regeneration
npj Regenerative Medicine
November 8, 2023
Jingyi Shen, Ying Wang, Fei Zheng, Shuo Cao, Qiu Lan, Kailin Xu, Bin Pan
Shanghai, China) containing 10% FBS for 72 h. Reagents
FICZ
(
HY-12451
),
CH-223191
(
HY-12684
), stattic (
HY-13818
) and colivelin (
HY-P1061A
) were purchased from
MedChemExpress
(Monmouth Junction, NJ, USA).
Recombinant murine IL-22
(3)
CD36+ cancer-associated fibroblasts provide immunosuppressive microenvironment for hepatocellular carcinoma via secretion of macrophage migration inhibitory factor
Cell Discovery
March 6, 2023
Gui-Qi Zhu, Zheng Tang, Run Huang, Wei-Feng Qu, Yuan Fang, Rui Yang, Chen-Yang Tao, Jun Gao, Xiao-Ling Wu, Hai-Xiang Sun,
et al.
1:1
) without or with neutralizing
ISO-1
(10 nM, #
HY-P7387
,
MedChemExpress
) and/or
Stattic
(100 nM,
HY-13818
,
MedChemExpress
) for 24 h, respectively. Uptake of fatty acids or lipoproteins, lipid peroxidation
(4)
Metformin attenuates fibroblast activation during pulmonary fibrosis by targeting S100A4 via AMPK-STAT3 axis
Frontiers in Pharmacology
February 3, 2023
Huimin Ji, Hongliang Dong, Yuejiao Lan, Yuqian Bi, Xuan Gu, Yongyue Han, Chongyang Yang, Minghan Cheng, Jian Gao
Pharmaceuticals Co., Ltd. Metformin (Cat. No. D150959) was purchased from Sigma-Aldrich.
Stattic
(Cat. No.
HY-13818
) was obtained from
MedChemExpress
, and Recombinant Human TGF-β1 (Cat. No.
100-21
) was purchased from
(5)
Chronic inflammation decreases HSC fitness by activating the druggable Jak/Stat3 signaling pathway
EMBO reports
January 9, 2023
Srdjan Grusanovic, Petr Danek, Maria Kuzmina, Miroslava K Adamcova, Monika Burocziova, Romana Mikyskova, Karolina Vanickova, Sladjana Kosanovic, Jana Pokorna, Milan Reinis,
et al.
below:
Stattic
treatment Stattic (Stat3 inhibitor) was purchased from
MedChemExpress
(catalog #:
HY‐13818
). WT and CMO
mice
were injected intraperitoneally with PBS control or
Stattic
(20 mg/kg). A total of
(6)
Ezh2Y641F mutations co-operate with Stat3 to regulate MHC class I antigen processing and alter the tumor immune response in melanoma
Oncogene
November 11, 2022
Sarah M. Zimmerman, Samantha J. Nixon, Pei Yu Chen, Leela Raj, Sofia R. Smith, Rachel L. Paolini, Phyo Nay Nay Lin, George P. Souroullas
(InVivoMAb anti-
mouse
CD8β Cat# BE0223 Lot# 733219O1) and
Stat3
inhibitor
STATTIC
(
MedChemExpress
Cat#
HY-13818
Batch# 21868) were administered intraperitoneally at 10 mg/kg.
For flow cytometry
analysis,
tumors
were
(7)
IL-20RB mediates tumoral response to osteoclastic niches and promotes bone metastasis of lung cancer
The Journal of clinical investigation
October 17, 2022
He Y, Luo W, Liu Y, Wang Y, Ma C, Wu Q, Tian P, He D, Jia Z, Lv X,
et al
.
protein was from
Peprotech
(catalog
200-19
-10). The
STAT3
inhibitors
napabucasin (
HY-13919
) and stattic (
HY-13818
) were obtained from
MedChemExpress
. The ELISA kits used were as follows:
GM-CSF
(
Proteintech
;
KE00003
(8)
Intestinal epithelial cell autophagy deficiency suppresses inflammation-associated colon tumorigenesis
Molecular Therapy - Nucleic Acids
June 14, 2022
Hao Liu, Jun Lou, Yunlong Liu, Zhen Liu, Jiansheng Xie, Jiachun Sun, Hongming Pan, Weidong Han
results were calculated in pg/mL.
Stattic
treatment The
STAT3
inhibitor
stattic (
MedChemExpress
, Cat#
HY-13818
) was dissolved in vehicle (10% DMSO, 40%
PEG300
, 5%
Tween-80
, 45% saline) followed by
intraperitoneal injection
(9)
Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma
Cell death & disease
May 25, 2022
Zheng ZY, Chu MY, Lin W, Zheng YQ, Xu XE, Chen Y, Liao LD, Wu ZY, Wang SH, Li EM,
et al
.
(
V1121
) was purchased from
Promega
.
Trametinib
(MEK1/2 inhibitor,
HY-10999
), Stattic (STAT3 inhibitor,
HY-13818
), and ruxolitinib (JAK1/2
inhibitor
,
HY-50856
) were obtained from
MedChemExpress
(MCE, China). Blasticidin
(10)
IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation
Nature communications
June 15, 2021
Hu F, Song D, Yan Y, Huang C, Shen C, Lan J, Chen Y, Liu A, Wu Q, Sun L,
et al
.
different experiments. Chloroquine (CQ; Cat#
C6628
) was obtained from
Sigma
.
Inhibitors
of
STAT3
(
Stattic
,
HY-13818
) and
JAK2
(
CHZ868
, Cat#
HY-18960
) were purchased from
MedChemExpress
.
5-Fluorouracil
(5-Fu; Cat#F6627),
(11)
Berberine suppresses bladder cancer cell proliferation by inhibiting JAK1-STAT3 signaling via upregulation of miR-17-5p
Biochemical Pharmacology
June 1, 2021
Yangyang Xia et al.
5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT, #M2128) were purchased from
Sigma
(St. Louis, MO, USA).
Stattic
(#
HY-13818
) was purchased from
MedChemExpress
(Monmouth Junction, NJ, USA).
Berberine chloride
and stattic were dissolved
(12)
A Positive Feedback Loop of lncRNA DSCR8/miR-98-5p/STAT3/HIF-1α Plays a Role in the Progression of Ovarian Cancer
Frontiers in Oncology
September 2, 2020
Lina Dong, Xuejiao Cao, Yi Luo, Guoqing Zhang, Dandan Zhang
miR-98-5p in cells. signal transducer and activator of transcription 3-specific
inhibitor
Stattic
(Cat. No.
HY-13818
) and HIF-1α specific
inhibitor
BAY 87-2243
(Cat. No.
HY-15836
) were purchased from
MedChemExpress
(Shanghai,
(13)
Crocin has pharmacological effects against the pathological behavior of colon cancer cells by interacting with the STAT3 signaling pathway
Experimental and Therapeutic Medicine
December 16, 2019
Jun Wang, Yupei Ke, Tao Shu
(
Thermo Fisher Scientific
, Inc.) at 37˚C and 5% CO2. Prior to
western blot analysis
,
HCT116 cells
were treated with
Stattic
(
HY‑13818
;
MedChemExpress
), according to the manufacturer's instructions, to
inhibit
the activity of the STAT3
(14)
JAK3/STAT3 oncogenic pathway and PRDM1 expression stratify clinicopathologic features of extranodal NK/T‑cell lymphoma, nasal type
Oncology Reports
April 12, 2019
Jumei Liu, Li Liang, Dong Li, Lin Nong, Yalin Zheng, Sixia Huang, Bo Zhang, Ting Li
14703
;
Cell Signaling Technology
, Inc., Danvers, MA, USA) and
Stattic
(1, 2, 5 and 10 µM) (cat. no.
HY-13818
;
MedChemExpress
, Inc., Shanghai, China) at indicated concentrations for 24 and 48 h, with dimethyl sulfoxide
(15)
Interleukin 22 Expands Transit-Amplifying Cells While Depleting Lgr5
+
Stem Cells via Inhibition of Wnt and Notch Signaling
Cellular and molecular gastroenterology and hepatology
January 1, 2019
Zha JM, Li HS, Lin Q, Kuo WT, Jiang ZH, Tsai PY, Ding N, Wu J, Xu SF, Wang YT,
et al
.
(
Merck Millipore
, Burlington, MA; 420099) or STAT3
inhibitor
Stattic
(
MedChemExpress
, Monmouth Junction, NJ;
HY-13818
) was added to ENR medium. Images were collected by using an inverted microscope (Olympus IX-73, Tokyo,
(16)
Nerve growth factor (NGF)-treated nitrocellulose enhances and directs the regeneration of adult rat dorsal root axons through intraspinal neural tissue transplants
Neuroscience letters
August 14, 1989
Houle JD, Johnson JE.
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Stattic from MedChemExpress
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