Vorinostat from MedChemExpress

Product Specs
ItemVorinostat
CompanyMedChemExpress
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberHY-10221
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.62%
FormulaC14H20N2O3
Research AreaInfection; Cancer
TypeChemical
Molecular Weight264.32
Quantity10 mM * 1 mL
Molecule NameVorinostat

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(1) Luminal breast cancer identity is determined by loss of glucocorticoid receptor activityEMBO Molecular MedicineDecember 7, 2023Stefan Prekovic, Theofilos Chalkiadakis, Merel Roest, Daniel Roden, Catrin Lutz, Karianne Schuurman, Mark Opdam, Liesbeth Hoekman, Nina Abbott, Tanja Tesselaar, et al.ribociclib (HY‐15777), alobresib (HY‐109050), molibresib (HY‐13032), birabresib (HY‐15743), vorinostat (HY‐10221), panobinostat (HY‐10224), and mocetinostat (HY‐12164). All of these drugs were purchased from MedChemExpress. Overexpression

(2) KLF5 Promotes Tumor Progression and Parp Inhibitor Resistance in Ovarian CancerAdvanced ScienceNovember 1, 2023Yong Wu, Siyu Chen, Yang Shao, Ying Su, Qin Li, Jiangchun Wu, Jun Zhu, Hao Wen, Yan Huang, Zhong Zheng, et al.using Cell Counting Kit‐8 (Yeasen, Shanghai, China), and the surviving fraction was calculated. SAHA (HY‐10221) and olaparib (HY‐10162) were purchased from MedChemExpress (Shanghai, China). In Vivo Assays Female

(3) Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancerClinical and Translational MedicineOctober 25, 2023Xin Sun, Guiqin Ye, Jiuzhou Li, Huafeng Shou, Gongxun Bai, Jianbin ZhangHY‐17559), CCCP (Cat No. HY‐100941), MG132 (Cat No. HY‐13259), CHX (Cat No. HY‐12320), SAHA (Cat No. HY‐10221). 4.3 siRNA and plasmids transient transfection The scrambled RNAi oligonucleotides and siRNAs targeting

(4) Inherited Retinal Degeneration: Towards the Development of a Combination Therapy Targeting Histone Deacetylase, Poly (ADP-Ribose) Polymerase, and CalpainBiomoleculesMarch 23, 2023Yujie Dong, Jie Yan, Ming Yang, Wenrong Xu, Zhulin Hu, François Paquet-Durand, Kangwei Jiaothe in vitro conditions. From P7 onwards, they were treated with different inhibitors: 0.1 μM SAHA (HY-10221; MedChemExpress, Sollentuna, Sweden), 1 μM Olaparib (HY-10162; MedChemExpress, Sollentuna, Sweden),

(5) Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/β-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stabilityMilitary Medical ResearchSeptember 27, 2022Zhi-Qiang Ma, Ying-Tong Feng, Kai Guo, Dong Liu, Chang-Jian Shao, Ming-Hong Pan, Yi-Meng Zhang, Yu-Xi Zhang, Di Lu, Di Huang, et al.P1400, Solarbio, Beijing, China). Melatonin (#14427, Cayman Chemical Company, Michigan, USA), SAHA (HY-10221, MedChemExpress, USA), Lf3 (HY-101486, MedChemExpress, USA) and 10058-F4 (HY-12702, MedChemExpress,

(6) Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagyActa pharmaceutica Sinica. BFebruary 1, 2022Sun X, Shu Y, Ye G, Wu C, Xu M, Gao R, Huang D, Zhang J.(MedChemExpress, HY-17589A), Hoechst (Beyotime, 33342), suberoylanilide hydroxamic acid (SAHA; MedChemExpress, HY-10221), and trichostatin A (TSA, MedChemExpress, HY-15144). 2.3 Small interfering RNA (siRNA) and plasmids

(7) Transcriptional control of a collagen deposition and adhesion process that promotes lung adenocarcinoma growth and metastasisJCI insightJanuary 11, 2022Tan X, Banerjee P, Liu X, Yu J, Lee S, Ahn YH, Creighton CJ, Kurie JM.5-azacytidine-2′-deoxycytidine (MilliporeSigma, A3656), TSA (MilliporeSigma, T1952), SAHA (MedchemExpress, HY- 10221), MS-275 (MedchemExpress, HY-12163), PD106 (MedchemExpress, HY-19348), LMK-235 (MedchemExpress, HY-18998),

(8) WEE1 inhibition induces anti-tumor immunity by activating ERV and the dsRNA pathwayThe Journal of experimental medicineJanuary 3, 2022Guo E, Xiao R, Wu Y, Lu F, Liu C, Yang B, Li X, Fu Y, Wang Z, Li Y, et al.#HY-10424, gefitinib/cat #HY-50895, UNC1215/cat #HY-15649, cisplatin/cat #HY-17394, vorinostat/cat #HY-10221, and A-485/cat #HY-10745 were from MedChemExpress. RNA-seq Purified total RNA from ID8 and OV90 cells cultured

(9) Pharmacological targeting of TNS3 with histone deacetylase inhibitor as a therapeutic strategy in esophageal squamous cell carcinomaAging (Albany NY)June 15, 2021Yang Shi, Zheng Xiang, Huiyu Yang, Suliman Khan, Ruizhe Li, Siran Zhou, Saif Ullah, Jiyu Zhang, Bingrong Liuinhibitory concentration (IC50) [33]. Cell viability assays LMK-235(Cat# HY-18998) and Vorinostat (Cat# HY-10221) were purchased from MedChemExpress (MCE, USA). KYSE150 and TE-1 cells, treated with LMK-235 for 48

(10) Technology of biomolecular design, with experiments on light control of the photochemical cycle in Halobacterium halobiumFEBS lettersApril 15, 1976Hess B.

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Vorinostat from MedChemExpress

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Vorinostat from MedChemExpress

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