GW 4064 from MedChemExpress

Product Specs
ItemGW 4064
CompanyMedChemExpress
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberHY-50108
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity98.92%
TypeChemical
Molecular Weight542.84
FormulaC₂₈H₂₂Cl₃NO₄
Research AreaMetabolic Disease; Cancer

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(1) Inhibiting Wnt Signaling Reduces Cholestatic Injury by Disrupting the Inflammatory AxisCellular and Molecular Gastroenterology and HepatologyAugust 12, 2023Mary Ayers, Karis Kosar, Yuhua Xue, Chhavi Goel, Matthew Carson, Elizabeth Lee, Silvia Liu, Eva Brooks, Pamela Cornuet, Michael Oertel, et al.there were n = 4 Mdr2 KO controls and n = 6 Mdr2 KO+Wnt-C59. Chemicals Wnt-C59 (#HY-15659), GW-4064 (HY-50108), and Trop (#HY-107418) were purchased from MedChemExpress (Monmouth Junction, NJ). OCA (#B4888) was

(2) BRD4 inhibition and FXR activation, individually beneficial in cholestasis, are antagonistic in combinationJCI InsightJanuary 11, 2021Hyunkyung Jung, Jinjing Chen, Xiangming Hu, Hao Sun, Shwu-Yuan Wu, Cheng-Ming Chiang, Byron Kemper, Lin-Feng Chen, Jongsook Kim Kemperpurchased from Dharmacon; AAV8-TBG-Cre (VB1724) and AAV8-TBG-GFP (VB1743) from Vector Biosystems; GW4064 (HY-50108), OCA (HY-12222), and JQ1 (HY-13030) from MedChemExpress; ANIT (N4525) from MilliporeSigma; and TNF-α

(3) FXR activation alleviates tacrolimus-induced post-transplant diabetes mellitus by regulating renal gluconeogenesis and glucose uptakeJournal of translational medicineDecember 13, 2019Li L, Zhao H, Chen B, Fan Z, Li N, Yue J, Ye Q.(1 mg/kg/day) and the FXR agonist GW4064 (30 mg/kg/day, MedChemExpress China, Shanghai, China, No. HY-50108). All three groups were intragastrically administered the treatments once a day for 3 months. Body weights

(4) Hyaluronan production in human rheumatoid fibroblastic synovial lining cells is increased by interleukin 1 beta but inhibited by transforming growth factor beta 1Annals of the rheumatic diseasesOctober 1, 1998Kawakami M, Suzuki K, Matsuki Y, Ishizuka T, Hidaka T, Konishi T, Matsumoto M, Kataharada K, Nakamura H.

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GW 4064 from MedChemExpress

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GW 4064 from MedChemExpress

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