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Protein Biochemistry
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GSK126
GSK126 from MedChemExpress
Be the first to write a review!
Citations:
(10)
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MedChemExpress for
GSK126
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Description
GSK2816126A
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
GSK126
Company
MedChemExpress
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
HY-13470
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.98%
Type
Chemical
Molecular Weight
526.67
Formula
C₃₁H₃₈N₆O₂
Research Area
Cancer
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MedChemExpress
1 Deer Park Dr, Suite Q
Monmouth Junction
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (10)
(1)
Delineating the interplay between oncogenic pathways and immunity in anaplastic Wilms tumors
Nature Communications
November 30, 2023
Xiaoping Su, Xiaofan Lu, Sehrish Khan Bazai, Linda Dainese, Arnauld Verschuur, Benoit Dumont, Roger Mouawad, Li Xu, Wenxuan Cheng, Fangrong Yan,
et al.
15140
-122]). The vorinostat (cat. no. HY-1022), entinostat (MS-275; cat. no. HY-12163),
GSK126
(cat. no.
HY-13470
), tazemetostat (EPZ-6438; cat. no.
HY-13803
), adavosertib (cat. no.
HY-10993
), ceralasertib (cat. no.
(2)
Calcineurin/NFATc3 pathway mediates myocardial fibrosis in diabetes by impairing enhancer of zeste homolog 2 of cardiac fibroblasts
BMC Cardiovascular Disorders
September 21, 2023
Lei Zhang, Huan-Huan Liu, Fan Yang, Zhi-Yuan Zhang, Ying Wu, Feng Li, Shi-Peng Dang, Zhen-Ye Zhang, Ling-Ling Qian, Ru-Xing Wang
CaN
inhibitor
,
Medchemexpress
,
HY15465
) [15], or 1 µmol/L
GSK126
(an
EZH2
inhibitor
,
Medchemexpress
,
HY13470
) to treat cells for 72 h. Cells were harvested after 72 h.
Western blot analysis
Rat heart tissues
(3)
SAM-Competitive EZH2-Inhibitors Induce Platinum Resistance by EZH2-Independent Induction of ABC-Transporters
Cancers
June 3, 2023
Groß E, Hilger RA, Schümann FL, Bauer M, Bouska A, Rohde C, Willscher E, Lützkendorf J, Müller LP, Edemir B,
et al
.
(approximately 10% reduction in cell viability or published concentrations) were used: 4 µM
GSK126
(
HY-13470
;
MedChemExpress
, Sollentuna, Sweden), 4 µM EPZ6438 (
HY-13803
;
MedChemExpress
, Sollentuna, Sweden), 125
(4)
Essential role of MALAT1 in reducing traumatic brain injury
Neural regeneration research
August 1, 2022
Wu N, Cheng CJ, Zhong JJ, He JC, Zhang ZS, Wang ZG, Sun XC, Liu H.
was also added into the culture media. Drugs Cells were cultured with the
EZH2
inhibitor
GSK126
(
HY-13470
,
Medchemexpress
, New Jersey, USA; 10 μM, 50 mM in dimethyl sulfoxide). Cells were cultured with the
(5)
EZH2 engages TGFβ signaling to promote breast cancer bone metastasis via integrin β1-FAK activation
Nature communications
May 10, 2022
Zhang L, Qu J, Qi Y, Duan Y, Huang YW, Zhou Z, Li P, Yao J, Huang B, Zhang S,
et al
.
μg/ml.
GSK126
(#
15415
), VS-6063 (#
17737
), and VS-4718 (#
17668
) were purchased from
Cayman Chemical
.
GSK126
(#
HY-13470
) and VS-6063 (#
HY-12289
) were purchased from
MedChemExpress
.
EPZ-6438
(#1463254-99-8) were purchased
(6)
CircGSK3B promotes RORA expression and suppresses gastric cancer progression through the prevention of EZH2 trans-inhibition
Journal of Experimental & Clinical Cancer Research
December 1, 2021
Xianxiong Ma, Hengyu Chen, Lei Li, Feng Yang, Chuanqing Wu, Kaixiong Tao
120,000×g). Stable cell lines were obtained by selection with puromycin. The
EZH2
inhibitor
(
GSK126
; MCE,
HY-13470
) was obtained from
MedChemExpress
company (New Jersey, USA). RNA extraction and
quantitative real-time polymerase chain reaction
(7)
Tumor-suppressive function of EZH2 is through inhibiting glutaminase
Cell Death & Disease
November 1, 2021
Yongfeng Liu et al.
medium changing. DMEM without glucose was obtained from Thermo Fisher Scientific (11966-025).
GSK126
(
HY-13470
),
BPTES
(
HY-12683
), TSA (
HY-15144
) were got from
MedChemExpress
(MCE) (NJ, USA). DCFH-DA Reactive Oxygen
(8)
Histone acetyltransferase 1 promotes gemcitabine resistance by regulating the PVT1/EZH2 complex in pancreatic cancer
Cell death & disease
September 25, 2021
Sun Y, Ren D, Zhou Y, Shen J, Wu H, Jin X.
working concentration 10 μM), MG132 (
HY-13259
,
MedChemExpress
; working concentration 10 μM), and
GSK126
(
HY-13470
,
MedChemExpress
; working concentration 10 μM).
Immunohistochemistry (IHC
)
Pancreatic cancer
tissue
(9)
Identification of Androgen Receptor Metabolic Correlome Reveals the Repression of Ceramide Kinase by Androgens
Cancers (Basel)
August 26, 2021
Laura Camacho et al.
used at 10µM.
GSK126
(EZH2
inhibitor
) was purchased from
MedChemExpress
(Monmouth Junction, NJ, USA;
HY-13470
), dissolved in DMSO, and used in a range of concentrations for 24 h.
C2 Ceramide
(N-acetoyl-D-erythro-sphingosine)
(10)
Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy
Cell Reports
July 20, 2021
Christopher J. Terranova et al.
proteins",, ,, "GSK-126 1346574–57-9, 5 mg",Caymen Chemical,CAT#NC0761027 "GSK-126, 500mg",
MedChemExpress
,CAT#
HY-13470
Vemurafenib
,
MedChemExpress
,CAT#
HY-12057
Trametinib
,
MedChemExpress
,CAT#
HY-10999A
3-Deazaneplanocin A
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GSK126 from MedChemExpress
Supplier Page
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