Oleic Acid-Water Soluble from MilliporeSigma

Product Specs
ItemOleic Acid-Water Soluble
CompanyMilliporeSigma
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberO1257
Applicationsmammalian cell culture
Quantity10MG

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MilliporeSigma

400 Summit Drive

Burlington, Massachusetts 01803

United States

Phone: (800)-645-5476
(800)-645-5439

Company Profile

Website: www.SigmaAldrich.com/

(1) Characterization of an in vitro steatosis model simulating activated de novo lipogenesis in MAFLD patientsiScienceOctober 20, 2023Kim W, Li M, Jin H, Yang H, Türkez H, Uhlén M, Zhang C, Mardinoglu A.induce media) for one week by 3 days + 2day + 2 days, a total of three times media exchange. Oleic acid (O1257, Sigma-Aldrich) was dissolved into 11%BSA in PBS. 25μM oleic acid was treated into cell culture media

(2) Impaired lipophagy induced-microglial lipid droplets accumulation contributes to the buildup of TREM1 in diabetes-associated cognitive impairmentAutophagyOctober 1, 2023Li Q, Zhao Y, Guo H, Li Q, Yan C, Li Y, He S, Wang N, Wang Q.accumulations, cells were treated with 5 μg/mL LPS (Sigma-Alrich, L6143) for 18 h, or 100 μM OA (Sigma-Alrich, O1257) for 12 h or 500 μM PA (Sigma-Aldrich, P5585) for 24 h. Then, the cells were fixed or collected for

(3) Myoglobin-mediated lipid shuttling increases adrenergic activation of brown and white adipocyte metabolism and is as a marker of thermogenic adipocytes in humansClinical and translational medicineDecember 1, 2022Christen L, Broghammer H, Rapöhn I, Möhlis K, Strehlau C, Ribas-Latre A, Gebhardt C, Roth L, Krause K, Landgraf K, et al.#157953) and subsequent oxygen exposure for 5 min. 71 Palmitic and oleic acid (Sigma, #P0500 and #O1257) were solubilized in chloroform and 2 μl (containing 2 pmol to 400 nmol of fatty acid) were spotted

(4) Cellular senescence in hepatocytes contributes to metabolic disturbances in NASHFront Endocrinol (Lausanne)August 22, 2022Laurianne Bonnet, Ida Alexandersson, Ritesh K. Baboota, Tobias Kroon, Jan Oscarsson, Ulf Smith, Jeremie BoucherIn some experiments, in order to create pro-steatotic conditions, 200 µM of oleic acid (Sigma-Merck, O1257) for IHH or 400 µM for HepG2 was added to culture medium containing 1% FBS (for both the –OA and +OA

(5) PI3Kα inhibitor CYH33 triggers antitumor immunity in murine breast cancer by activating CD8⁺T cells and promoting fatty acid metabolismJournal for immunotherapy of cancerAugust 1, 2021Sun P, Zhang X, Wang RJ, Ma QY, Xu L, Wang Y, Liao HP, Wang HL, Hu LD, Kong X, et al.Shanghai, China, No. ST025) complex was prepared as reported.33 The water-soluble oleic acid (Sigma, No. O1257) was dissolved in distilled water and sterilized. CFSE-labeled CD8+T cells cultured in glucose-free

(6) RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawalCell reportsJuly 27, 2021Hussain SS, Tran TM, Ware TB, Luse MA, Prevost CT, Ferguson AN, Kashatus JA, Hsu KL, Kashatus DF.(MDH),Abcepta,Cat# SM1000a Fatty Acid-Free BSA,Fisher Scientific,Cat# BP9704100 Oleic acid,Sigma-Aldrich,Cat# O1257 Gluthathione Sepharose 4B,GE Healthcare,Cat# GE17-0756-01 Critical commercial assays,Critical commercial

(7) CD36-mediated ferroptosis dampens intratumoral CD8⁺ T cell effector function and impairs their antitumor abilityCell metabolismMay 4, 2021Ma X, Xiao L, Liu L, Ye L, Su P, Bi E, Wang Q, Yang M, Qian J, Yi Q.acid,Sigma-Aldrich,M3128 palmitic acid,Sigma-Aldrich,P0500; CAS: 57-10-3 oleic acid,Sigma-Aldrich,O1257 arachidonic acid,Sigma-Aldrich,10931; CAS: 506-32-1 "cis-5,8,11,14,17-eicosapentaenoic acid",Sigma-Aldrich,E2011;

(8) SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formationeLifeApril 23, 2021Sanders DW, Jumper CC, Ackerman PJ, Bracha D, Donlic A, Kim H, Kenney D, Castello-Serrano I, Suzuki S, Tamura T, et al.drug",Genistein,Selleck Chemicals,S1342, "Chemical compound, drug",Oleic acid (MBCD-conjugated),Sigma-Aldrich,O1257, "Chemical compound, drug",Cholesterol (MBCD-conjugated),Sigma-Aldrich,C4951, "Chemical compound,

(9) SOCS2 Suppresses Inflammation and Apoptosis during NASH Progression through Limiting NF-κB Activation in MacrophagesInternational journal of biological sciencesJanuary 1, 2021Li S, Han S, Jin K, Yu T, Chen H, Zhou X, Tan Z, Zhang G.incubator with 5% CO2. For cell treatment, the FFAs mixture was prepared with oleic acid (OA; Sigma, O1257) and palmitic acid (PA; Sigma, P0500-10G) in a 2:1 ratio and used at a 0.5 mmol/L final concentration,

(10) PTPROt aggravates inflammation by enhancing NF-κB activation in liver macrophages during nonalcoholic steatohepatitisTheranosticsJanuary 1, 2020Jin K, Liu Y, Shi Y, Zhang H, Sun Y, Zhangyuan G, Wang F, Yu W, Wang J, Tao X, et al.incubator with 5% CO2. For cell treatment, the FFAs mixture was prepared with oleic acid (OA; Sigma, O1257) and palmitic acid (PA; Sigma, P0500-10G) in a 2:1 ratio and used at a 0.5 mmol/L final concentration,

(11) An effective protocol for pharmacological defatting of primary human hepatocytes which is non-toxic to cholangiocytes or intrahepatic endothelial cellsPloS oneJanuary 1, 2018Boteon YL, Wallace L, Boteon APCS, Mirza DF, Mergental H, Bhogal RH, Afford S.polyunsaturated omega-6 linoleic acid (L5900; Sigma-Aldrich) and the monounsaturated omega-9 oleic acid (O1257; Sigma-Aldrich) all at a final concentration of 0.25mM. This concentration was determined by performing

(12) Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patientsScientific ReportsMay 11, 2017Franck Chiappini et al.(C18:1n-7) and oleic acid (C18:1n-9) were all obtained from Sigma (Ref# M3128, 43051, S4751, P9417, V0384, O1257, respectively). Fatty acids were dissolved in absolute ethanol at a concentration of 40 mM stock solutions,

(13) Extra-pancreatic invasion induces lipolytic and fibrotic changes in the adipose microenvironment, with released fatty acids enhancing the invasiveness of pancreatic cancer cellsOncotargetMarch 14, 2017Takashi Okumura et al.Wako), 10% fetal bovine serum (FBS), 100 μg/ml streptomycin, and 100 units/ml penicillin. Oleic acid (O1257), palmitoleic acid (P9417), and linoleic acid (L5900) were obtained from Sigma-Aldrich and dissolved

(14) A20 Attenuates FFAs-induced Lipid Accumulation in Nonalcoholic SteatohepatitisInternational Journal of Biological SciencesNovember 25, 2015Luoyan Ai, Qingqing Xu, Changwei Wu, Xiaohan Wang, Zhiwei Chen, Dazhi Su, Xiaoke Jiang, Antao Xu, Qing Lin, Zhuping Fanboth containing 10% FBS. For cell treatment, the FFAs mixture was prepared with oleic acid (OA; Sigma, O1257) and palmitic acid (PA; Sigma, P0500-10G) in a 2:1 ratio and used at a 0.5 mmol/L final concentration. Construction

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Oleic Acid-Water Soluble from MilliporeSigma

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