Oleic acid from MilliporeSigma

Product Specs
ItemOleic acid
CompanyMilliporeSigma
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberO1383
Applicationsmammalian cell culture
Quantity1G, 25G, 5G

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MilliporeSigma

400 Summit Drive

Burlington, Massachusetts 01803

United States

Phone: (800)-645-5476
(800)-645-5439

Company Profile

Website: www.SigmaAldrich.com/

(1) Single‐cell transcriptomics stratifies organoid models of metabolic dysfunction‐associated steatotic liver diseaseThe EMBO JournalDecember 11, 2023Anja Hess, Stefan D Gentile, Amel Ben Saad, Raza‐Ur Rahman, Tim Habboub, Daniel S Pratt, Alan C Mullen(R&D Systems 240‐B‐002), palmitic acid (PA, Sigma Aldrich P0500), and oleic acid (OA, Sigma Aldrich O1383). HLO media was changed to injury media on day 21. Isolated HLOs were resuspended in the final injury

(2) Melatonin as a Repairing Agent in Cadmium- and Free Fatty Acid-Induced LipotoxicityBiomoleculesDecember 7, 2023Anna Migni, Francesca Mancuso, Tiziano Baroni, Gabriele Di Sante, Mario Rende, Francesco Galli, Desirée BartoliniSt. Louis, MI, USA), oleic Acid (BioReagent from Sigma-Aldrich, St. Louis, MI, USA; product number: O1383), and palmitic Acid (P0500, Sigma-Aldrich, St. Louis, MI, USA); cadmium chloride (CdCl2; 202908, Sigma-Aldrich,

(3) Transcriptomics reveal a molecular signature in the progression of nonalcoholic steatohepatitis and identifies PAI‑1 and MMP‑9 as biomarkers in in vivo and in vitro studiesMolecular Medicine ReportsNovember 28, 2023Yao Zhao, Mirensha Yakufu, Chong Ma, Baicai Wang, Jianhua Yang, Junping Hu(FFAs) were prepared by combining palmitic acid (PA; cat. no. P0500, MilliporeSigma) and oleic acid (OA; O1383; MilliporeSigma) in a 1:2 molar ratio of respectively. The stock solutions of PA (78 mM) and OA (354

(4) Fatty acids abrogate the growth-suppressive effects induced by inhibition of cholesterol flux in pancreatic cancer cellsCancer Cell InternationalNovember 17, 2023Yuchuan Li, Manoj Amrutkar, Anette Vefferstad Finstadsveen, Knut Tomas Dalen, Caroline S. Verbeke, Ivar P. Gladhaugin DMEM supplemented with 1% FBS, with different combinations of lipids and drugs. Oleic acid (OA; #O1383; Sigma-Aldrich, St Louis, MO, USA) was bound to bovine serum albumin (#A8806; Sigma-Aldrich) in a 2.5:1

(5) Knockout of STE20-type kinase TAOK3 does not attenuate diet-induced NAFLD development in miceMolecular MedicineOctober 20, 2023Ying Xia, Emma Andersson, Mara Caputo, Emmelie Cansby, Francesca Sedda, Ferran Font-Gironès, Johan Ruud, Yeshwant Kurhe, Bengt Hallberg, Hanns-Ulrich Marschall, et al.(SIC001; Sigma-Aldrich) using Lipofectamine RNAiMax. Cells were incubated with 25–50 µmol/l oleic acid (O1383, Sigma-Aldrich) for 48 h prior to harvest. Histology and immunofluorescence microscopy Liver and eWAT

(6) BATF relieves hepatic steatosis by inhibiting PD1 and promoting energy metabolismeLifeSeptember 15, 2023Zhiwang Zhang, Qichao Liao, Tingli Pan, Lin Yu, Zupeng Luo, Songtao Su, Shi Liu, Menglong Hou, Yixing Li, Turtushikh Damba, et al.High-tech Co. Ltd,TP2330055MC,standar: AIN93 "Chemical compound, drug",Oleic acid (OA),Sigma-Aldrich,Cat# O1383, "Chemical compound, drug",Palmitic acid (PA),Sigma-Aldrich,Cat# P0500, "Software, algorithm",Image

(7) HAMLET effect on cell death and mitochondrial respiration in colorectal cancer cell lines with KRAS/BRAF mutationsJournal of Cancer Research and Clinical OncologySeptember 1, 2023Justas Žilinskas, Darius Stukas, Aldona Jasukaitienė, Jurgita Šapauskienė, Rasa Banienė, Sonata Trumbeckaitė, Saulius Švagždys, Marco Cicciu, Žilvinas Dambrauskas, Antanas Gulbinas, et al.at 37 °C in a 5% CO2 atmosphere. Human alpha-lactalbumin (Cat. No. L7269) and oleic acid (Cat. No. O1383) were purchased from Sigma-Aldrich, Germany. 3-(4,5-Dimethylthiazol-2yl)-2,5-diphenyltetrazolium bromide

(8) Mimicking Wagyu beef fat in cultured meat: Progress in edible bovine adipose tissue production with controllable fatty acid compositionMaterials Today BioAugust 1, 2023Fiona Louis, Mai Furuhashi, Haruka Yoshinuma, Shoji Takeuchi, Michiya MatsusakiAldrich, P4060), erucic acid (45629-F), elaidic acid (Sigma Aldrich, 45,089), oleic acid (Sigma Aldrich, O1383), palmitoleic acid (Sigma Aldrich, 76,169), myristoleic acid (Sigma Aldrich, 41,788). The 300 μL of

(9) Rhamnetin ameliorates non-alcoholic steatosis and hepatocellular carcinoma in vitroMolecular and Cellular BiochemistryAugust 1, 2023Mahmoud A. Shatta, Marwa O. El-Derany, Abdullah A. Gibriel, Hala O. El-Mesallamygrade. Rhamnetin (17799) Sigma-Aldrich, Oil red O (O0625) Sigma-Aldrich, PA (PO500) Sigma-Aldrich, OA (O1383) Sigma-Aldrich, Bovine serum albumin-BSA (160069), Sigma, USA. Fetal Bovine serum (10270-106), Trypsin-versene

(10) A Plasmodium membrane receptor platform integrates cues for egress and invasion in blood forms and activation of transmission stagesScience AdvancesJune 16, 2023Ronja Marie Kuehnel, Emma Ganga, Aurélia C. Balestra, Catherine Suarez, Matthias Wyss, Natacha Klages, Lorenzo Brusini, Bohumil Maco, Nicolas Brancucci, Till S. Voss, et al.nucleic acid gel stain was from Thermo Fisher Scientific (catalog no. S7563). Oleic acid (Sigma-Aldrich, O1383) and palmitic acid (Sigma-Aldrich, P5585) were solved in 100% ethanol (stocks 30 mM). Aliquots were

(11) Evaluating the function of murine quiescent hematopoietic stem cells following non-homologous end joining-based genome editingSTAR ProtocolsJune 9, 2023Kohei Shiroshita, Hiroshi Kobayashi, Keiyo TakuboA4503-100G Palmitic acid,Wako Pure Chemical Corporation,Cat# 165-00102 Oleic acid,Sigma-Aldrich,Cat# O1383-1G Cholesterol,Sigma-Aldrich,Cat# C3045-5G Methanol,Nacalai Tesque,Cat# 21914-03 Sodium hydroxide,Wako

(12) Exposure to dietary fatty acids oleic and palmitic acid alters structure and mechanotransduction of intestinal cells in vitroArchives of ToxicologyJune 1, 2023Janice Bergen, Martina Karasova, Andrea Bileck, Marc Pignitter, Doris Marko, Christopher Gerner, Giorgia Del Faveromethods Treatment compounds Palmitic acid [Sigma-Aldrich P0500-10G; 25–500 µM], oleic acid [Sigma-Aldrich O1383-1G; 25–500 µM], and cerulenin, Cephalosporium caerulens [EMD Millipore Corp M.W.223.3; 5–50 µM] and

(13) Obesity impairs cardiolipin-dependent mitophagy and therapeutic intercellular mitochondrial transfer ability of mesenchymal stem cellsCell death & diseaseMay 13, 2023Sagar S, Faizan MI, Chaudhary N, Singh V, Singh P, Gheware A, Sharma K, Azmi I, Singh VP, Kharya G, et al.A,Sigma,A8674 11,Rotenone,Sigma,R8875 12,Sodium Palmitate,Sigma,P9767 13,Stearic Acid,Sigma,S4751 14,Oleic acid,Sigma,O1383 ,Plasmids,Plasmids,Plasmids 1,pLYS1-FLAG-MitoGFP-HA,Addgene,50057 2,pCMV-VSV-G,Addgene,8454 3,pCMV-dR8.2

(14) Alterations in Cytoskeleton and Mitochondria in the Development and Reversal of Steatosis in Human HepatocytesCellular and Molecular Gastroenterology and HepatologyApril 20, 2023Letao Fan, Aslihan Gokaltun, Sarah Maggipinto, Yoshinori Kitagawa, Jeevendra Martyn, Heidi Yeh, Basak E. Uygun, Martin L. Yarmush, O. Berk Ustawhich was based on the lean medium with a supplement of 800 μmol/L oleic acid (unsaturated fatty acid, O1383; Sigma-Aldrich), and 400 μmol/L palmitic acid (saturated fatty acid, F0500; Sigma-Aldrich) that were

(15) Differential Roles of CD36 in Regulating Muscle Insulin Response Depend on Palmitic Acid LoadBiomedicinesFebruary 28, 2023Sun J, Su Y, Chen J, Qin D, Xu Y, Chu H, Lu T, Dong J, Qin L, Li W.obtained from Equitech-Bio (#BAH66, Kerrville, TX, USA). Palmitate acid was obtained from Sigma–Aldrich (#O1383, St. Louis, MO, USA). 2.3. RNA Interference siRNA duplexes that target mouse CD36 (siCD36-1: 5′-GGAUGACAACUUCACAGUUTT-3′;

(16) Cholesterol esters form supercooled lipid droplets whose nucleation is facilitated by triacylglycerolsNature CommunicationsFebruary 17, 2023Calvin Dumesnil, Lauri Vanharanta, Xavier Prasanna, Mohyeddine Omrane, Maxime Carpentier, Apoorva Bhapkar, Giray Enkavi, Veijo T. Salo, Ilpo Vattulainen, Elina Ikonen, et al.with cell culture media at 1/10 v/v ratio. The resulting solution was incubated with pure oleic acid (#O1383 SigmaAldrich) to obtain a final concentration of 1 mM. The resulting mixture was vortexed and then sonicated

(17) Decreased autophagosome biogenesis, reduced NRF2, and enhanced ferroptotic cell death are underlying molecular mechanisms of non-alcoholic fatty liver diseaseRedox BiologyFebruary 1, 2023Pengfei Liu, Annadurai Anandhan, Jinjing Chen, Aryatara Shakya, Matthew Dodson, Aikseng Ooi, Eli Chapman, Eileen White, Joe GN. Garcia, Donna D. Zhangantibodies Fatty Acid Supplement (F7050), palmitic acid (P0050), palmitoleic acid (P9417), oleic acid (O1383), stearic acid (S4751), sulforaphane (S6317), MTT (M2003), rapamycin (R8781), and ferrostatin-1 (SML0583)

(18) Long-term statins administration exacerbates diabetic nephropathy via ectopic fat deposition in diabetic miceNature communicationsJanuary 24, 2023Huang TS, Wu T, Wu YD, Li XH, Tan J, Shen CH, Xiong SJ, Feng ZQ, Gao SF, Li H, et al.Specifically, HK-2 cells were subjected to starvation in a serum-free medium overnight, then treat with OA (O1383, Sigma-Aldrich) (120 μM) and insulin 2.4 μM for 24 h, and separately subjected to treated with MK-2206

(19) BACH1-induced ferroptosis drives lymphatic metastasis by repressing the biosynthesis of monounsaturated fatty acidsCell death & diseaseJanuary 20, 2023Xie X, Tian L, Zhao Y, Liu F, Dai S, Gu X, Ye Y, Zhou L, Liu X, Sun Y, et al.For ferroptosis intervention with OA, 5×105 KYSE150-BACH1-OE cells, with or without 400 µM OA (Cat# O1383, Sigma–Aldrich) pretreatment were injected into the tail veins of NCG mice (n = 6 per group). The body weights

(20) BAMLET (Bovine α-lactalbumin made lethal to tumor cells) inhibits autophagy flux and induces apoptosis via down-regulation of protein kinase CK1α and attenuation of the AKT/p-ß-catenin (S552) pathway in RAS-mutated human colorectal HCT 116 cellsIran J Basic Med SciJanuary 1, 2023Hamid Behrouj, Pooneh Mokarram3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide (MTT) (M2128), α-Lactalbumin from bovine milk (L6010), Oleic acid (O1383), Anti-rabbit IgG, anti-mouse IgG, and LC3B antibody (L7543) were purchased from Sigma-Aldrich (St.

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Oleic acid from MilliporeSigma

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