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Protein Biochemistry
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Guanosine
Guanosine from MilliporeSigma
Be the first to write a review!
Citations:
(34)
Supplier Page
Supplier Page from
MilliporeSigma for
Guanosine
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Guanosine
Company
MilliporeSigma
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
G6264
Applications
mammalian cell culture
Quantity
1G, 25G, 5G
Add to Compare List
MilliporeSigma
400 Summit Drive
Burlington
,
Massachusetts
01803
United States
Phone
: (800)-645-5476
(800)-645-5439
Company Profile
Website:
www.SigmaAldrich.com/
Citations (34)
(1)
Direct stimulation of de novo nucleotide synthesis by O-GlcNAcylation
Nature chemical biology
January 1, 2024
Chen L, Zhou Q, Zhang P, Tan W, Li Y, Xu Z, Ma J, Kupfer GM, Pei Y, Song Q,
et al
.
rate analysis after replenishment of IAGUC and NAD, inosine (I4125), adenosine (
A4036
), guanosine (
G6264
), uridine (
U3003
), cytidine (
C4654
) and β-nicotinamide adenine dinucleotide (N7004) were obtained from
(2)
Ribonucleotide synthesis by NME6 fuels mitochondrial gene expression
The EMBO journal
September 18, 2023
Grotehans N, McGarry L, Nolte H, Xavier V, Kroker M, Narbona-Pérez ÁJ, Deshwal S, Giavalisco P, Langer T, MacVicar T.
,
New England BioLabs
,
N0446S
EmbryoMax 100× Nucleosides,
Millipore
,
ES‐008‐D
Adenosine
,
Sigma
,
A4036
Guanosine
,
Sigma
,
G6264
Cytidine
,
Sigma
,
C4654
Uridine
,
Sigma
,
U3003
Lipofectamine
RNAi
MAX,
Thermo Fisher Scientific
,
13778150
Lipofectamine
(3)
Metabolic classification suggests the GLUT1/ALDOB/G6PD axis as a therapeutic target in chemotherapy-resistant pancreatic cancer
Cell Reports Medicine
September 1, 2023
Yunguang Li, Shijie Tang, Xiaohan Shi, Jingwen Lv, Xueyuan Wu, Yehan Zhang, Huan Wang, Juan He, Yiqin Zhu, Yi Ju,
et al.
thymidine (
Sigma
,
T1895
), with a final concentration of 240um; Purine nucleosides include
Guanosine
(
Sigma
,
G6264
) and adenosine (
Sigma
,
A4036
), with a final concentration of 200um; R5P (MCE, 207671-46-3) with a final
(4)
Tracer metabolomics reveals the role of aldose reductase in glycosylation
Cell Reports Medicine
June 20, 2023
Silvia Radenkovic, Anna N. Ligezka, Sneha S. Mokashi, Karen Driesen, Lynn Dukes-Rimsky, Graeme Preston, Luckio F. Owuocha, Leila Sabbagh, Jehan Mousa, Christina Lam,
et al.
,
Thermo Fisher
,
21335
Glycerol
,
Thermo Fisher
,G33-4
Glycerol
,VWR chemicals,56-81-5 "
Guanosine
, suitable for
cell culture
",
Sigma
,
G6264
-1G
HEPES
,Thermo Fisher,BP310-1
HEPES
,Sigma,H3375 "HEPES sodium salt, 99%",
ACROS organics
,
215000010
IGEPAL®-
(5)
IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia
EMBO molecular medicine
January 11, 2023
Liu X, Sato N, Yabushita T, Li J, Jia Y, Tamura M, Asada S, Fujino T, Fukushima T, Yonezawa T,
et al
.
Cat#194172; CAS:24280–93‐1) or FF‐10501‐01 (FUJIFILM Corporation) together with or without 100 μM
Guanosine
(#
G6264
‐6G,
Sigma‐Aldrich
or
ACROS ORGANICS
, Cat#
411130250
; CAS:118–00‐3). After 72 h, we added 10 μl of the
(6)
Overexpressed c-Myc Sensitizes Cells to TH1579, a Mitotic Arrest and Oxidative DNA Damage Inducer
Biomolecules
November 29, 2022
Henriksson S, Calderón-Montaño JM, Solvie D, Warpman Berglund U, Helleday T.
bortezomib (Selleckchem, Houston, TX, USA; cat# PS-341) and dNTPs (
Sigma-Aldrich
; cat#
U3003
,
C4654
,
G6264
,
A4036
). TH588 and TH1579 were synthesized in-house, whereas AZ19 compound was provided by AstraZeneca
(7)
Rewiring glucose metabolism improves 5-FU efficacy in p53-deficient/KRASG12D glycolytic colorectal tumors
Communications Biology
October 31, 2022
Marlies C. Ludikhuize, Sira Gevers, Nguyen T. B. Nguyen, Maaike Meerlo, S. Khadijeh Shafiei Roudbari, M. Can Gulersonmez, Edwin C. A. Stigter, Jarno Drost, Hans Clevers, Boudewijn M. T. Burgering,
et al.
5-FU administration. Nucleosides (25 µM each, all
Sigma
: adenosine #
A4036
, thymidine #T9250, guanine #
G6264
and cytidine #
C4654
) were added together with 5-FU. Treatments with palbociclib (1 µM, selleckchem,
(8)
Thymidine rescues ATR kinase inhibitor-induced deoxyuridine contamination in genomic DNA, cell death, and interferon-α/β expression
Cell reports
September 20, 2022
Sugitani N, Vendetti FP, Cipriano AJ, Pandya P, Deppas JJ, Moiseeva TN, Schamus-Haynes S, Wang Y, Palmer D, Osmanbeyoglu HU,
et al
.
Sigma,Z761079
Adenosine
,
Sigma-Aldrich
,
A4036
-5G
Thymidine
,
Sigma-Aldrich
,
T1895
-1G
Cytidine
,
Sigma-Aldrich
,
C4654
-1G
Guanosine
,
Sigma-Aldrich
,
G6264
-1G
EmbryoMax Nucleosides (100x
),
Millipore Sigma
,
ES-008-D
5-ethynyl-2′-deoxyuridine (EdU),
Invitrogen
,
A10044
5-iodo-2′-deoxyuridine
(9)
TLR7 gain-of-function genetic variation causes human lupus
Nature
May 1, 2022
Brown GJ, Cañete PF, Wang H, Medhavy A, Bones J, Roco JA, He Y, Qin Y, Cappello J, Ellyard JI,
et al
.
of 500 nM. The ratio of DOTAP to RNA (at 80 μM) was 3.52 µg μl−1 of ssRNA.
Guanosine
(
Sigma-Aldrich
,
G6264
, 10 mg freshly resuspended in 176.5 μl DMSO (200 mM stock solution)) and R848 (
Invivogen
,
tlrl-r848
)
(10)
Fundamental behaviors emerge from simulations of a living minimal cell
Cell
January 20, 2022
Zane R. Thornburg, David M. Bianchi, Troy A. Brier, Benjamin R. Gilbert, Tyler M. Earnest, Marcelo C.R. Melo, Nataliya Safronova, James P. Sáenz, András T. Cook, Kim S. Wise,
et al.
HCL,Sigma-Aldrich,51030
Uracil
,
Sigma-Aldrich
,U0750
Thymine
,
Sigma-Aldrich
,T0376
Adenosine
,
Sigma-Aldrich
,
A4036
Guanosine
,
Sigma-Aldrich
,
G6264
Uridine
,
Sigma-Aldrich
,U3750
Thymidine
,
Sigma-Aldrich
,T9250
Cytidine
,
Sigma-Aldrich
,C122106
KnockOut™ (serum replacement
(11)
Orally acquired cyclic dinucleotides drive dSTING-dependent antiviral immunity in enterocytes
Cell Reports
December 28, 2021
Elisha Segrist, Mark Dittmar, Beth Gold, Sara Cherry
endotoxin free, Invivogen #tlrl-nacdg) or guanosine (200 μg/mL, for use
in cell culture
, Milipore
Sigma
, #
G6264
) and infected as above. c-di-GMP or guanosine were replaced three days later with
virus
and intestines
(12)
ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism
Cancer & metabolism
December 3, 2021
Khare S, Kim LC, Lobel G, Doulias PT, Ischiropoulos H, Nissim I, Keith B, Simon MC.
,
Sigma Aldrich
,
P0290
WST-1,Sigma Aldrich,5015944001
Adenosine
,
Sigma Aldrich
,
A4036
Guanosine
,
Sigma Aldrich
,
G6264
Thymidine
,
Sigma Aldrich
,
T1895
Cytidine
,
Sigma Aldrich
,
C4654
Trolox
,
Cayman Chemical
,
10011659
N-acetyl-l-cysteine
,
Sigma Aldrich
(13)
Precise CAG repeat contraction in a Huntington’s Disease mouse model is enabled by gene editing with SpCas9-NG
Communications Biology
December 1, 2021
Seiya Oura, Taichi Noda, Naoko Morimura, Seiji Hitoshi, Hiroshi Nishimasu, Yoshitaka Nagai, Osamu Nureki, Masahito Ikawa
Thermo Fisher Scientific), 30 μM
Adenosine
(
A4036
,
Sigma–Aldrich
, St. Louis, MO, USA), 30 μM
Guanosine
(
G6264
,
Sigma–Aldrich
), 30 μM
Cytidine
(
C4654
,
Sigma–Aldrich
), 30 μM
Uridine
(
U3003
,
Sigma–Aldrich
), 10 μM
(14)
METTL3 Inhibitors for Epitranscriptomic Modulation of Cellular Processes
ChemMedChem
October 6, 2021
Elena V. Moroz‐Omori, Danzhi Huang, Rajiv Kumar Bedi, Sherry J. Cheriyamkunnel, Elena Bochenkova, Aymeric Dolbois, Maciej D. Rzeczkowski, Yaozong Li, Lars Wiedmer, Amedeo Caflisch
external
calibration
curve generated using adenosine (Sigma‐Aldrich, 01890–5G), guanosine (
Sigma‐Aldrich
,
G6264
‐1G), m6A (Chemie Brunschwig, CBLQB‐1055‐1 g), m1A (MedChem Express, MCE‐HY‐113081), m6Am (Toronto Research
(15)
Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells
Nature metabolism
July 1, 2021
Schwartz AJ, Goyert JW, Solanki S, Kerk SA, Chen B, Castillo C, Hsu PP, Do BT, Singhal R, Dame MK,
et al
.
(
A4036
–5G,
Sigma
) 100 μM Cytosine (C3056–1G,
Sigma
), 100 μM
Thymidine
(
T1895
–1G,
Sigma
), 100 μM
Guanosine
(
G6264
–1G,
Sigma
).
HCT116 cells
were pretreated with either vehicle or 100 μM FG4592 (Selleckchem) for 16 hours
(16)
KCTD19 and its associated protein ZFP541 are independently essential for meiosis in male mice
PLOS Genetics
May 7, 2021
Seiya Oura, Takayuki Koyano, Chisato Kodera, Yuki Horisawa-Takada, Makoto Matsuyama, Kei-ichiro Ishiguro, Masahito Ikawa
Thermo Fisher Scientific), 30 μM
Adenosine
(
A4036
,
Sigma- Aldrich
, St. Louis, MO, USA), 30 μM
Guanosine
(
G6264
,
Sigma-Aldrich
), 30 μM
Cytidine
(
C4654
,
Sigma-Aldrich
), 30 μM
Uridine
(
U3003
,
Sigma-Aldrich
), 10 μM
(17)
Induction of autophagy increases the proteolytic activity of reservosomes during
Trypanosoma cruzi
metacyclogenesis
Autophagy
February 1, 2021
Antonella Denise Losinno, Santiago José Martínez, Carlos Alberto Labriola, Carolina Carrillo, Patricia Silvia Romano
T8625), 100 mg/L
L-tyrosine
(
Sigma
, T3754), 10 mg/L adenosine (
Sigma
,
A4036
), 10 mg/L guanosine (
Sigma
,
G6264
), 50 mg/L glucosamine-HCl (Sigma, 1294207), 4 mg/L folic acid (Sigma, F7876), pH 7.3. Parasites Epimastigotes
(18)
Guanosine-Mediated Anxiolytic-Like Effect: Interplay with Adenosine A1 and A2A Receptors
International Journal of Molecular Sciences
December 5, 2020
Monica Frinchi et al.
methods to perform the described experiments (3Rs) were found. Drugs. The following drugs were used: GUO (
G6264
Sigma-Aldrich
St. Louis, MO, USA) and nonselective ARs ligand ADO (
A3377
Sigma-Aldrich
St. Louis, MO,
(19)
Cell-Cycle-Associated Expression Patterns Predict Gene Function in Mycobacteria
Current Biology
October 1, 2020
Aditya C. Bandekar, Sishir Subedi, Thomas R. Ioerger, Christopher M. Sassetti
Proteins" VCC234718,[43],N/A C109,[50],N/A Guanine-98%,Millipore-Sigma,G11950 Guanosine > = 98%,
Millipore-Sigma
,
G6264
Spectinomycin dihydrochloride pentahydrate
,
Millipore-Sigma
,
S4014
Critical Commercial
Assays
,Critical
(20)
ADAR1-Dependent RNA Editing Promotes MET and iPSC Reprogramming by Alleviating ER Stress
Cell stem cell
August 6, 2020
Guallar D, Fuentes-Iglesias A, Souto Y, Ameneiro C, Freire-Agulleiro O, Pardavila JA, Escudero A, Garcia-Outeiral V, Moreira T, Saenz C,
et al
.
Sigma-Aldrich
,
A4036
;
Cytidine
:
Sigma-Aldrich
,
C4654
;
Thymidine
:
Sigma-Aldrich
,
T1895
;
Guanosine
:
Sigma-Aldrich
,
G6264
), 1% penicillin and streptomycin and 1000 U/ml of recombinant leukemia inhibitory factor (LIF). For
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Guanosine from MilliporeSigma
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View Company Product Page
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