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Protein Biochemistry
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DL-α-Difluoromethylornithine (hydrochloride hydrate)
DL-α-Difluoromethylornithine (hydrochloride hydrate) from Cayman Chemical
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Citations:
(2)
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DL-α-Difluoromethylornithine (hydrochloride hydrate)
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Description
An irreversible inhibitor of ornithine decarboxylase that suppresses polyamine biosynthesis; displays antiangiogenic, cytostatic, and antiparasitic effects
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
DL-α-Difluoromethylornithine (hydrochloride hydrate)
Company
Cayman Chemical
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
16889
Format
A crystalline solid
Research Area
Angiogenesis, Cancer, Immunology & Inflammation, Infectious Disease
Molecular Weight
236.6
Quantity
50 mg
Purity
≥98%
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (2)
(1)
Post-fast refeeding enhances intestinal stem cell-mediated regeneration and tumourigenesis through mTORC1-dependent polyamine synthesis
Research Square
January 24, 2023
Shinya Imada, Heaji Shin, Saleh Khawaled, Sven W. Meckelmann, Charles A. Whittaker, Renan Oliveira Correa, Dikshant Pradhan, Gizem Calibasi-Kocal, Luiza Martins Nascentes Nascentes, Gabriele Allies,
et al.
Express,HY-70063
Cycloheximide
,
Millipore Sigma
,
C7698
Puromycin dihydrochloride
,
Millipore Sigma
,
P8833
DL-a-Difluoromethylornithine,
Cayman
,
16889
Matrigelâ„¢,
Corning
,
356231
Advanced DMEM
,
GIBCO
,
12491015
EGF,
Peprotech
,
315-09
Noggin,
Peprotech
,
250-38
R-spondin,
Peprotech
,
315-32
N-acetyl-l-cystine,Sigma
(2)
LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages
Nature
September 8, 2022
Zheng Wei, Joonseok Oh, Richard A. Flavell, Jason M. Crawford
(BioLegend,
575302
) in triplicate for 16 hours. In some experiments as indicated, 1 mM DFMO (
Cayman
,
16889
) was supplemented during differentiation to
inhibit
ODC1. After a 16-hour stimulation period, culture
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DL-α-Difluoromethylornithine (hydrochloride hydrate) from Cayman Chemical
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