Fig 1: Cytokine secretion of anti-CD38 RP02 and 028 CAR-T cells. CAR-T cells were coincubated with the CD38+ cell lines, i.e., RPMI8226, Daudi, Raji, THP1, or CD38- cell line K562 at E:T ratio of 4:1 for 24 h. Cytokine secretion by anti-CD38 RP02 and 028 CAR-T cells was measured using the AlphaLISA assay. a–d) Graph shows the secretion of IFN-?, TNF-a, GM-CSF, and IL-2. Data are represented as mean ± s.e.m. of n = 3 technical replicates.